Nebilet tabs 5mg #28

Nebilet user manual

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The drug Nebilet belongs to the group of beta-adrenoblockers of the 3rd generation, which has vasodilating properties.

Medicinal composition and form of release

The drug Nebilet is available in the form of white tablets, convex on both sides with a cross-shaped notch for the convenience of division. Tablets are packed in blisters of 7 or 14 pieces in a cardboard box with the attached detailed description.
Each tablet contains 5 mg of the active active ingredient Nebivolol, as well as auxiliary substances, including lactose, which may not be tolerated by patients with congenital lactase deficiency.

Pharmacological properties

The drug Nebilet belongs to the group of beta-blockers. The active active substance of the drug has a pronounced hypotensive, antiarrhythmic and antianginal effect on the body.
Under the influence of the drug, blood pressure values ​​are normalized, the patient's stamina is increased with minor physical exertion and stress.
The therapeutic effect of the drug is noticeable after 1-2 weeks from the start of treatment, and after 8 weeks a stable effect of the drug is observed.
Since under the influence of the drug reduces the need for cardiac muscle in oxygen, then in patients with angina, the frequency of seizures decreases significantly.

Indications for use

Tablets Nebilet are prescribed to patients for the treatment of the following pathological conditions:
    Ischemic heart disease as a prophylaxis of angina attacks;
    Arterial hypertension;
    Heart failure of chronic course as part of complex therapy.

Contraindications

The drug should be taken only as directed by the doctor. Before starting therapy, it is recommended that you read the instructions in detail, as the tablets have such contraindications:
    Acute congestive heart failure;
    Decompensated chronic heart failure;
    Low blood pressure;
    Slow heartbeat (less than 60 beats per minute);
    Acute myocardial infarction;
    Cardiogenic shock;
    Metabolic acidosis;
    Severe liver or kidney disease, accompanied by a violation of the function of the body;
    Cases of bronchospasm in the anamnesis or diagnosed bronchial asthma;
    Prolonged depression with suicidal thoughts;
    Myasthenia gravis;
    Raynaud's disease and other disorders of the peripheral circulation;
    Individual lactose intolerance, lactase insufficiency;
    Age under 18 years due to unidentified safety and effectiveness;
    Increased individual sensitivity to one of the constituent components of the drug.
The drug also has relative contraindications, that is, certain limitations, during which therapy is possible only under the supervision of a doctor. Such states include:
    Diabetes;
    Angina of princemetal;
    Chronic obstructive pulmonary disease;
    The age of patients older than 70 years;
    Hyperfunction of the thyroid gland;
    Psoriasis;
    Atopic dermatitis, wet eczema.

Method of administration and dosage regimen

Tablets are for oral use. The drug is taken once a day, preferably at the same time, at the dose indicated by the doctor. The medicine can be taken regardless of food, drinking a pill with a sufficient amount of liquid.
Patients suffering from hypertension or ischemic heart disease receive an initial dose of ½ tablet once a day. If the therapeutic effect is insufficient or absent, then the dose of the drug is increased with the permission of the doctor to 1 tablet. The drug can be used as part of complex therapy with other drugs that lower blood pressure, as well as as an independent tool.
Patients with moderate renal failure and those older than 65 years of age receive an initial dose of ½ tablet, which if necessary increase under the supervision of a doctor. The maximum daily dose of the drug should not exceed 10 mg, or 2 tablets of 5 mg, which are divided into 2 divided doses.
For patients with chronic heart failure, the initial dose of the drug is selected by the doctor individually, which, if necessary, gradually increase, maintaining intervals of at least 1 week. The maximum daily dose of the drug is 10 mg.
At the initial stage of therapy, as well as with every increase in the initial dose, the patient must have the first hours under the supervision of a doctor. In this case, the specialist measures blood pressure, pulse parameters and respiratory function. If everything is in order, the patient is released home.

Use among pregnant women and nursing mothers

Tablets treatment A nebilet during pregnancy is possible only if there are life indications, when the health benefits of the expectant mother exceed the probable danger to the health of the fetus. According to the results of studies carried out in the fetus or newborn, against the background of the mother's use of this medication, there was a decrease in blood pressure, a slowing of the heart rate and a decrease in the level of glucose in the blood.
If necessary, the pregnant woman should be under the constant supervision of a doctor who monitors the full value of uteroplacental blood flow and fetal response to therapy. A few days before the expected date of birth, treatment with the drug is recommended to be discontinued, and if this is not possible, then the newborn should be closely monitored for the first 3 days.
The active ingredient of the drug Nebilet is excreted in breast milk, so if it is necessary to treat a nursing mother, stop lactation so as not to harm the baby.

Side effects

Against the background of drug treatment, patients may develop adverse reactions:
    On the part of the nervous system - headaches, fatigue and lethargy, weakness, a feeling of crawling on the skin, a decrease in sensitivity in the limbs, dizziness, depression, sleep disturbance, insomnia, in rare cases, a syncope is possible;
    On the part of the gastrointestinal tract - nausea, pain in the epigastric region, vomiting, bloating, increased gas formation, constipation, diarrhea, pain in the right hypochondrium, increased activity of liver transaminases;
    From the side of the cardiovascular system - the development of heart failure, a sharp drop in blood pressure, including collapse, bradycardia, the development of Raynaud's syndrome;
    Allergic reactions - a rash on the skin, urticaria, the development of angioedema, bronchospasm, exacerbation of atopic dermatitis and psoriasis.
Against the background of long-term use of this drug, patients wearing contact lenses complained of excessive dry eyes.

An overdose of the drug

If the dose recommended by a specialist is met and the intervals between dose adjustments are correct, an overdose of tablets is unlikely. With the accidental use of large doses of the drug, the patient develops signs of an overdose that are expressed by the following clinical symptoms:
    Decrease in blood pressure, dizziness, collapse;
    Decrease in heart beat rate per minute;
    Nausea and vomiting;
    Development of acrocyanosis;
    Cardiogenic shock;
    Inhibition of respiratory function;
    In severe cases, coma and cardiac arrest.
Treatment of an overdose consists of immediate washing of the stomach and administration of enterosorbents. In case of collapse or development of heart failure, the patient undergoes symptomatic treatment.

Interaction of the drug with other drugs

With simultaneous use of the drug with other antihypertensive agents, the risk of side effects and orthostatic hypotension increases.
Against the background of treatment with Nebilet can reduce the therapeutic effect of hypoglycemic agents, therefore, people with diabetes require a correction of the dose of insulin or hypoglycemic agents.
The simultaneous use of this drug with tricyclic antidepressants, sedatives or barbiturates can enhance the antihypertensive effect of nebivolol.

special instructions

The drug should not be stopped abruptly, the withdrawal of therapy is carried out gradually within 7-10 days, in patients with coronary heart disease this period is not less than 14 days.
At the initial stage of treatment, the patient should daily measure blood pressure and heart rate parameters. Persons with impaired renal function in the history during the course of treatment should regularly monitor the usefulness of the organ.
If against the background of taking the drug in the patient there is a pronounced bradycardia (less than 60 beats / min), then the treatment with tablets should be stopped immediately.
With care, tablets should be taken to people with psoriasis, atopic dermatitis and bronchial asthma, as against the background of therapy, the condition can worsen and the disease worsens.
Patients who are scheduled surgical intervention with general anesthesia should always inform the doctor about the use of this medication.
Patients with chronic obstructive pulmonary disease treatment with the drug is carried out with caution and on indications, as against the background of therapy, the attacks of bronchospasm may become more frequent and worse.
Persons with a history of allergic anamnesis should be careful when using Nebilet tablets, since treatment can increase the sensitivity of the body to allergens and increase the severity of anaphylactic reactions.
Since at the initial stage of therapy the drug may cause dizziness in the patient, during this period, care should be taken when driving a car and the technique that requires the patient to have a high concentration of attention.

Terms of sale and storage of the medicine

You can buy Nebilet without a prescription. Tablets should be kept away from children in a cool place, where direct sunlight does not reach. If the storage conditions of the preparation are observed, Nebilet can be stored for 3 years from the date of production date, which is indicated on the package. At the end of the expiration date, the medication should not be taken orally.