Norbactin tabs 400mg #20

User manual for Norbactin

Reed more and buy Norbactin online

Composition

The main active ingredient of the drug is norfloxacin.
Norbactin the following auxiliary components: microcrystalline cellulose, sodium lauryl sulphate, silica colloidal anhydrous, talc-purified, croscarmellose sodium, corn starch, magnesium stearate.
The shell contains the following substances: hypromellose, purified talc, purified water, macrogol 400, titanium dioxide.

Form release

The drug is available in tablets.

Pharmacological action

Antibacterial agent. It has a wide range of actions.

Pharmacodynamics and pharmacokinetics

Getting into the body, the drug affects the bacterial enzyme DNA gyrase. It destabilizes the DNA chain, resulting in the death of bacteria. Bactericidal effect occurs quite quickly. The development of plasmid-mediated resistance is minimal.
The drug affects most aerobic gram-negative microorganisms, as well as some gram-positive ones. It is a potent antiseptic agent.
The medicine is well absorbed from the gastrointestinal tract. However, you should not take it while eating, as this reduces its effectiveness. For better assimilation it should be consumed on an empty stomach.
The maximum concentration of the drug is 1-2 hours after ingestion. The degree of binding with proteins – 14%. It is widely distributed in tissues, but does not penetrate the bones and the Central nervous system. Bioavailability is about 40%, the elimination half-life is 3.5 to 6.5 hours, but high concentrations found in the tissues longer.
The drug is partially processed in the liver. In some numbers is deduced with bile, but mostly with urine and feces.

Indications Norbactin

Norbactin is used for cystitis, pyelonephritis, urethritis, as well as bacterial infections of the gastrointestinal tract, genital organs and uncomplicated gonorrhea:
prostatitis;
endometritis;
cervicitis;
salmonellosis;
shigellosis.
Indications Norbactin also involve the use of patients with granulocytopenia and diarrhea in travelers as a preventive measure.

Contraindications

The drug can not be taken for those who have hypersensitivity to its components, as well as patients with severe renal insufficiency and pregnant.

Side effect

Norbactin, typically, well conveyed. There may be gastrointestinal disorders, as well as from the Central nervous system in the form of drowsiness and headache. Very rarely there are allergic reactions.

Instructions for use of Norbactin

If the patient was prescribed Norbactin, the instructions for use include various dosages, which depend on what tablets are used. On 400 mg means 2 times a day accept at:
urinary tract infections - within 7-10 days;
repeated or chronic urinary tract infections with exacerbations – within a month, and then, if necessary, apply 400 mg per day for up to 12 weeks;
chemoprophylaxis before and after urological operations;
intestinal infections - within 5 days;
acute uncomplicated cystitis-within 3 days.
400 mg once a day is prescribed, if the indications for the use of Norbaktina following:
prevention of traveler's diarrhea;
renal failure.
In acute uncomplicated gonococcal infection instruction on the use of Norbactin provides reception 800 mg once.

Overdose

With an overdose of the drug, dizziness, vomiting, cold sweat, nausea, drowsiness, and puffy facial expression are possible without changes in the main hemodynamic parameters.
As a treatment, gastric lavage and adequate hydration therapy with forced diuresis are prescribed. In addition, it is necessary to check up and keep in a hospital under the supervision of specialists for several days.

Interaction

The absorption of Norbactin makes it difficult to use antacids that contain aluminum and magnesium, as well as drugs with iron, sucralfate and zinc. Between their use should be a break of at least 4 hours.
In addition, this tool reduces the clearance of theophylline and the effect of nitrofurans, as well as increases the content of indirect anticoagulants and cyclosporine in the blood serum.
The drug should be with caution be taken in conjunction with the tools that reduce the seizure threshold, otherwise it may cause epileptiform seizures.
Simultaneous reception of Norbactin and means, lowering arterial pressure, can cause its sharp decrease. So the heart rate and ECG readings need to be clearly monitored.

Terms of sale

The prescription is not required to buy Norbactin online.

Storage conditions

The drug should be stored in a dry place at a temperature no higher than 25 °C.
Shelf life - three years.

Feedback about the Norbactin

The numerous reviews about the Norbactin indicate that the medication in most cases turns out to be really effective. On the forums, many ask, is an antibiotic or not, since some do not receive these funds. However, those who have already tried this drug, note its speed.
Side effects reviews of Norbactin practically misleading. There is information about the appearance of minor heartburn and other problems with the gastrointestinal tract, but the symptoms quickly pass with a decrease in dosage. The doctors at this facility are also mostly positive.