Epigen intim spray 0.1% 60ml
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Epigen spray instruction for useYou can buy Epigen intim spray on this pagepharmachologic effectAntiviral for external and local use. Glycyrrhizic acid is active against DNA and RNA-containing viruses, including various strains of..
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Epigen spray instruction for use
You can buy Epigen intim spray on this page
pharmachologic effect
Antiviral for external and local use. Glycyrrhizic acid is active against DNA and RNA-containing viruses, including various strains of the viruses Herpes simplex, Varicella zoster, human papillomaviruses, cytomegaloviruses. Antiviral action is associated, apparently, with the induction of the formation of interferon. Interrupts the replication of viruses in the early stages, causes the virion to emerge from the capsid, thereby preventing its penetration into the cells. This is due to selective dose-dependent inhibition of phosphorylating kinase P. It interacts with virus structures, changing the different phases of the viral cycle, which is accompanied by irreversible inactivation of virus particles (in a free state outside cells), blocking the introduction of active viral particles through the cell membrane inside the cell, viruses to the synthesis of new structural components.
Inhibits viruses in concentrations that are non-toxic to normally functioning cells.
The virus strains resistant to acyclovir and iodo-uridine are highly sensitive to glycyrrhizic acid.
It also has an anti-inflammatory, analgesic and tissue regeneration-improving effect, both with early manifestations of viral infection and with ulcer forms.
Indications
Treatment of infections of genital organs caused by the Herpes simplex type 2 virus (both in acute primary and in recurrent course); treatment of skin infections caused by the Varicella zoster virus (as part of combination therapy); treatment of skin and mucous membrane infections caused by human papillomavirus; treatment of nonspecific vaginitis, colpitis.
Preventing common viral infections transmitted sexually.
Contraindications
Hypersensitivity to glycyrrhizic acid.
Dosage
Individual, depending on the indications for use.
Side effects
Rarely: allergic reactions.
Drug Interactions
With the simultaneous use of glycyrrhizic acid with other antiviral drugs (acyclovir, iodoridine, interferon), potentiation of antiviral action is noted.
special instructions
In the treatment of skin infections caused by the Varicella zoster virus, the external use of glycyrrhizic acid should be combined with the intake of specific antiviral drugs.
During the treatment period it is not recommended to use inducers of interferon synthesis.
If signs of irritation of the skin or mucous membranes appear, treatment should be discontinued.
Pregnancy and lactemia
The use during pregnancy and during lactation is possible by absolute indications.
In experimental studies, embryotoxic and teratogenic effects of glycyrrhizic acid have not been established.