Baclosan 25mg #50

Instruction for Baclosan

You can buy Baclosan online

Composition

Tablets contain 10 or 25 mg of active substance Baclosan.
Additional elements: magnesium stearate, gelatin, lactose, ethyl cellulose, potato starch, talc.

Form of issue

Pills.

pharmachologic effect

Baclosan - what is it? The medicine is a central muscle relaxant.

Pharmacodynamics and pharmacokinetics

The active substance is a GABA-stimulator derived from gamma-aminobutyric acid. The mechanism of action is aimed at suppressing intermediate neurons, reducing the excitability of the terminal sections of sensitive, afferent fibers, suppressing monosynaptic, polysynaptic transmission of nerve impulses, which leads to a decrease in the prestress of muscle tissue.
The drug Baclosan does not affect neuromuscular transmission. The medication can facilitate active and passive kinesitherapy, increase the amount of movement in the joints, weaken the clonic convulsions and painful spasms in neurological diseases, which are manifested by the spasticity of skeletal musculature.

Indications for use

Baclosan is prescribed for spasticity in stroke, multiple sclerosis, spinal diseases (traumatic, tumorous, degenerative, infectious), meningitis, craniocerebral trauma, alcoholism (affector pathology), infantile cerebral palsy.

Contraindications

Baclosan is not used in Parkinson's disease, psychosis, history of seizures, epilepsy, intolerance to the main substance, atherosclerosis of the cerebral vessels, chronic renal failure.
When bearing pregnancy, ulcerative lesions of the digestive tract, with cerebrovascular insufficiency, breastfeeding, children under 12 and elderly persons, Baclosan is administered with caution.

Side effects

Baclosan causes asthenia, dizziness, drowsiness, vomiting, nausea, paresthesia, a drop in blood pressure, constipation, diarrhea, urinary retention, gait disturbance, confusion, tremor, ataxia, myasthenia, myalgia, depression, euphoria, apathy, enuresis, dysuria, hallucinations , paresis of accommodation, nystagmus, reduction of convulsive threshold, convulsions.
Long-term therapy causes disturbances in the liver system.
Tablets Baclosan, instructions for use (Method and dosage)
The drug is taken before meals, inside.
The initial dosage is 5 mg three times a day, then every three days the dose of the drug Baclosan is increased by 5 mg to achieve a therapeutic effect. The maximum dosage for adults is 100 mg per day under conditions of in-patient observation.
The final dosage is chosen taking into account such a decrease in muscle tone, which will not worsen the motor functions and will not lead to excessive myasthenia gravis.
People with hypersensitivity are prescribed 5-10 mg per day with a possible subsequent increase in the dose.
When carrying out hemodialysis, with CRF, the daily dosage is 5 mg.
Baclosan is canceled within 1-2 weeks gradually.

Instructions for use of Baclosan in children

At the age of one to two, 10-20 mg of substance are prescribed per day, two to six years - 20-30 mg per 24 hours, six to ten years - 30-60 mg per day. At the age of more than ten years the maximum dose is 1.5-2 mg per 1 kg.

Overdose

Overdose is manifested by coma, confusion, muscle hypotension, oppression of the respiratory center.
Requires the appointment of diuretic drugs, a plentiful drink, with respiratory depression - carrying artificial ventilation.
Antidote is not developed.

Interaction

Baclosan is able to enhance the action of medications that affect the work of the central nervous system, ethanol, anti-gout and hypotensive drugs.
Excitation, confusion, hallucinations are noted with concurrent administration of levodopa, carbidopa with levodopa.
Tricyclic antidepressants can increase the severity of muscle tone decline.

Storage conditions

In a place inaccessible to children at a temperature of no more than 25 degrees Celsius.
Shelf life - Not more than three years.

special instructions

Side effects of the drug Baclosan may have a transient nature. It is important to be able to distinguish the side effect from the signs of the underlying disease.
Patients with epilepsy are prescribed medication without concomitant withdrawal of antiepileptic medications.
In diabetes mellitus, the pathology of the hepatic system is regularly monitored by the level of blood sugar, the activity of liver enzymes.

Baclosan affects the concentration of attention and management of motor vehicles.

Reviews of Baclosan

Effective drug for controlling muscle rigidity. Quickly relaxed stiff muscles, eliminates clonic convulsions and spasms.
In the reviews of Baclosan, mention is made of the side effects of the drug, such as: nausea and vomiting.
Medication can also cause drug addiction, the consequences of which are very sad, even to death. Addicts, as a rule, consume a large amount of this drug, receiving the strongest side effects, in an attempt to get the necessary psychedelic state. Baclosan in a large dosage "priot" or causes a so-called "trip", which can result in a dropper or fatal outcome.
Dependence on this type of substance is very dangerous, since quitting using drugs is always more difficult than starting.