Doxycyclinum caps 100mg #10

Doxycyclinum instruction for use

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Doxycyclinum is an antibiotic from the group of tetracyclines and is assigned to a patient for the treatment of inflammatory and infectious diseases of various origins.

Form of formulation and composition of the preparation

Doxycyclinum is available in capsules for oral use, 10 units in blisters, in a cardboard box with the attached detailed instructions. Each capsule contains 100 mg of active ingredient - Doxycyclinum hydrochloride, as well as a number of auxiliary components.

Pharmacological properties of the drug

Doxycyclinum belongs to the group of tetracyclines and is an antibiotic of synthetic origin. If the capsule enters the active ingredient, it enters the common bloodstream. The drug penetrates directly into the cells that infect the infection, destroying them and preventing the spread of the pathological process through the body.
Doxycyclinum has a high therapeutic activity against gram-positive and gram-negative flora, namely staphylococcus, streptococcus, clostridia, listeria, klebsiella, gonococcus, pale plastic, salmonella, enterobacteria and others. The drug is highly effective against those microorganisms, which manifests its resistance to penicillins and antibiotics of other groups.
The drug has no therapeutic effect on Pseudomonas aeruginosa, fungal pathogens, proteic strains.

Indications for use

Doxycyclinum is prescribed for the treatment of the following pathologies:
Inflammatory and infectious diseases of the respiratory system - bronchitis (acute and chronic), pneumonia, bronchopneumonia, tracheitis, laryngitis, pulmonary empyema, lung abscess;
Infectious processes of the nasal and pharyngeal organs - pharyngitis, otitis, tonsillitis, sinusitis, sinusitis;
Inflammatory diseases of the urogenital system of infectious origin - pyelonephritis, cystitis, urethritis, gonorrhea, orchitis, epididymitis, urogenital mycoplasmosis, cervicitis, endocervicitis;
Exacerbation of chronic cholecystitis;
Cholangitis;
Dysentery;
Gastroenterocolitis;
Infectious lesions of soft tissues - furuncles, carbuncles, abscesses, phlegmon, panaritium, attachment of a secondary bacterial infection in burns and wounds;
Syphilis, proctitis, prostatitis, chlamydia.
The drug is also prescribed for prophylaxis after surgical interventions or traveling to countries where it is easy to catch listeriosis, dysentery, cholera.

Contraindications for use

Doxycyclinum can be taken only as directed by a doctor. Before starting therapy, the patient should carefully read the attached instructions, since the medicine has the following contraindications for use:
Individual intolerance to the components of the product;
The presence in the past of severe allergic reactions to drugs from the group of tetracyclines;
Lactose intolerance;
Lactase insufficiency;
Age under 12 years;
Leukopenia;
Severe violations of the liver and kidneys;
The patient's body weight is less than 45 kg.

Dosing and Administration

Capsules Doxycyclinum is intended for oral administration. The drug is taken half an hour before meals, without opening, squeezed with enough water. The daily dose of the drug and the duration of the course of treatment largely depends on the diagnosis, the severity of the clinical manifestations of the disease, the presence of complications, the patient's body weight and individual characteristics of the organism.
According to the instructions, Doxycyclinum is prescribed 1 capsule 1 time per day for 3-5 days. In rare cases, the course of therapy can be extended to 7-10 days under the supervision of a doctor.
Patients with impaired liver function require an individual selection of a daily dose.

Use of the drug during pregnancy and lactation

Capsules Doxycyclinum is not prescribed for the treatment of pregnant women. The active substance of the capsules easily penetrates the placenta to the fetus and causes severe malformations of the skeleton, the organs of the hematopoietic system, and the liver.
If a woman took Doxycyclinum and had a pregnancy, you should contact the gynecologist as soon as possible and tell him about the therapy that was passed. In some cases, this pregnancy has to be interrupted.
The use of the drug during the breastfeeding period is prohibited, since the active substance of the capsules penetrates into the breast milk and can cause disturbances in the internal organs of the child. If necessary, lactation should be stopped.

Side effects

Against the background of therapy with Doxycyclinum, patients often develop the following side effects:
    From the nervous system - paresthesia, headaches, dizziness, increased rates of intracranial pressure, toxic brain damage;
    One hundred sides of the digestive canal - nausea, a feeling of heaviness in the right hypochondrium, vomiting, diarrhea, anorexia, enlarged liver, exacerbation of chronic diseases of the stomach and duodenum, dysphagia, glossitis, development of enterocolitis;
    Blurred vision, double vision, ringing in the ears;
    Tachycardia, change in electrocardiogram indicators;
    Hemolytic anemia, thrombocytopenia, eosinophilia, decreased prothrombin index;
    Allergic reactions - urticaria, anaphylactic shock, rash on the skin, hyperemia, swelling of the mucous membranes of the respiratory tract;
    Change in the color of tooth enamel;
    Candidiasis of the vagina.

Overdose of the drug

With prolonged use of the drug in large doses, the patient develops the following signs of an overdose:
    Toxic liver damage, oppression of its functions, the development of severe hepatic insufficiency;
    Convulsions;
    Inhibition of respiratory function and heart function;
    Abundant vomiting, diarrhea, against which the patient develops dehydration;
    Development of renal failure.
When large doses of the drug are administered and the signs of an overdose are developed, the patient is washed with the stomach, administered orally activated carbon. If necessary, the patient is symptomatically treated. Antidote does not exist, hemodialysis with an overdose is not effective.

Interaction of the drug with other drugs

With the simultaneous use of Doxycyclinum capsules with antacids or enterosorbents, the therapeutic effectiveness of the antibiotic is reduced, which should be considered and taken at different times of the day.
If you need to use Doxycyclinum with anticoagulants, you need a correction of the dose of the latter.
The drug reduces the effectiveness of oral contraceptives, which should be warned by patients who prefer this method of protection from an unplanned pregnancy.
With the simultaneous use of the drug with ethanol, barbiturates, rifampicin, phenytoin, accelerated excretion of Doxycyclinum from the body is observed, which significantly reduces its therapeutic effect.
With the simultaneous use of the drug with vitamin A, the patient is more likely to develop elevated intracranial pressure against the background of this drug interaction.

special instructions

Since the preparation irritates the mucous membranes of the digestive tract, it is recommended to take the capsule with plenty of water or take the medicine shortly before meals.
Since under the influence of the drug in the patient the likelihood of photosensitivity increases, during the course of therapy, stay under direct sunlight should be limited.
If it is necessary to take capsules for more than 3 days, the patient should be monitored for liver function, kidney function and clinical blood picture.
On the background of drug therapy, the patient can change the color of the enamel of the teeth, which acquires a gray or yellow tint.
According to the results of medical studies, the drug has an embryotoxic effect, so the use of Doxycyclinum during pregnancy is strictly contraindicated. If a woman took the drug and did not know that she was pregnant, you should definitely inform the gynecologist about it. As a rule, such a pregnancy must be interrupted by artificial means.
Against the background of drug treatment in women, the development of persistent vaginal candidiasis is possible, therefore, in order to avoid this, it is recommended to take simultaneously with Doxycyclinum preparations of yogurt or lacto and bifidobacteria to maintain the normal microflora of the genital tract.
Since the patient may experience drowsiness and lethargy against the background of drug therapy, during the treatment period it is recommended to refrain from driving the car and controlling complex mechanisms that require increased concentration of attention.

Storage conditions

Capsules should be stored away from children at a temperature of not more than 25 degrees. Shelf life of the medicine is 36 months from the date of production, at its expiration the product is recyclable.