Nitroxoline tabs 50mg #50

Nitroxoline user manual

You can buy Nitroxoline here

Composition

The drug contains the active ingredient - nitroxoline.
Additional components: sucrose, povidone, aerosil, magnesium carbonate basic water, talc, titanium dioxide pigment, paraffin, beeswax, yellow-orange dye.

Form of issue

The main form of the drug is tablets in a shell, packaged in 10 pcs. in cell packs, 5 in a pack.

pharmachologic effect

Nitroxoline tablets have antibacterial action.

Pharmacodynamics and pharmacokinetics

This drug is an antibacterial agent derived from 8-hydroxyquinoline. Its effect is due to selective inhibition of the production of bacterial DNA. Nitroxoline activity is manifested in relation to known gram-positive bacteria and Gram-negative bacteria, some species of fungi.
As a result of ingestion, Nitroxoline-UBF is sufficiently absorbed from the digestive tract. Excretion occurs with the help of the kidneys, almost unchanged. In this case, high concentrations of the main substance are predominantly determined in the urine composition.

Indications Nitroxoline

The main indications for the use of Nitroxoline:
    treatment of infectious and inflammatory diseases of the urinary tract, for example: pyelonephritis, cystitis, urethritis, epididymitis, infected adenoma or carcinoma of the prostate;
    preventive maintenance of infectious complications during diagnostics and medical procedures - catheterization or cystoscopy, as well as after or during operations in the kidney and genitourinary tract.

Contraindications

Taking tablets is not recommended when:
    violations of kidney function, which may be accompanied by oligo- or anuria;
    severe liver disease;
    deficiency of glucose-6-phosphate dehydrogenase;
    neuritis;
    cataract;
    pregnancy, lactation;
    high sensitivity to quinolines.

Side effects

In most cases, the development of side effects occurs when patients take the drug, even without knowing what these pills help. In this case, deviations in the activity of the digestive system can be noted, for example, nausea, vomiting, loss of appetite, and sometimes abnormalities in the functioning of the liver.
Perhaps the manifestation of allergic reactions - skin rash and itching.
More often there are disturbances in the activity of the nervous system, manifested by ataxia, headache, paresthesia and polyneuropathy. Long-term use can cause optic neuritis.
In general, as is known, nitroxoline is an antibiotic, therefore undesirable effects affecting the functioning of various organs and systems, including cardiovascular, are not ruled out.
Nitroxoline tablets, instructions for use (Method and dosage)
As reported in the instructions for use of Nitroxoline-UBF, the tablets are taken orally, preferably after meals. The dosage of the drug is determined by the attending physician. On average, adult patients are prescribed 0.1 to 4 single doses per day. Duration of treatment can be 2-3 weeks.
If necessary, repeated courses are held after 2 weeks. The purpose of the tablets is also conducted to prevent postoperative infections in the kidney or urinary tract, and it is recommended to take 0.1 g of the drug 4 times a day for 2-3 weeks.

overdose

Cases of drug overdose may be accompanied by symptoms such as: vomiting, nausea, or general weakness. Treatment includes gastric lavage, intake of enterosorbents and symptomatic therapy.

interaction

The combined use of nitroxoline with drugs from the tetracycline group can enhance the effect of each drug. The simultaneous use of Nystatin and Levorin may enhance their action. The combination with nitrofurans causes a negative neurotropic effect, so they can not be taken together.

Storage conditions

Tablets are stored in a dry, dark place and protected from children.
Shelf life - 4 years.

Reviews about nitroxoline

As the reviews on nitroxoline show, many patients use this drug for cystitis. It should be noted that this tool is well known to women. However, some of them are interested, Nitroxoline tablets - from what they are and how to take the medicine correctly.
In most cases, reviews of Nitroxoline with cystitis confirm the rather high effectiveness of these tablets. But there are also reports when the medicine did not help to quickly eliminate the unpleasant symptoms of the disease.
Especially often there are discussions about how to take nitroxoline during pregnancy, although during this period it is contraindicated. However, sometimes women are wondering whether it is possible to take these pills during pregnancy and what are the consequences? In this case, experts do not recommend self-treatment, and when symptoms immediately go to the doctor.
Sometimes this medicine is prescribed for children, but most parents after a careful study of the annotation doubt whether it is possible to take the pill to patients at an early age. They also find out whether Nitroxoline is an antibiotic or not, and at what age is it prescribed for cystitis?
Experts recommend that before taking these pills, they should take tests and find out how sensitive the pathogen microorganisms are to the action of this antibiotic. Thanks to this you can understand how effective this treatment will be.
Until patients receive test results, antibiotic treatment is not recommended. But you can use local antimicrobials, not forgetting about a plentiful drink, for example, herbal decoctions.
In addition, you should check with your doctor for possible replacement options, and if this drug is not suitable for treatment, find out how you can quickly find effective treatment. Only with this approach can we hope that health will be fully restored in a short time.