Unidox Solutab tabs 100mg #10

Unidox Solutab instruction for use

You can buy Unidox Solutab on this page

Composition

One tablet of the drug contains 0.1 g of doxycycline antibiotic active ingredient + excipients (MCC, giprolose, saccharin, colloidal silicon dioxide, lactose monohydrate, hypromellose, magnesium stearate).

Form of issue

Round tablets, biconvex form, yellowish color, on each tablet an inscription 173.

pharmachologic effect

Antibacterial agent, antibiotic of the tetracycline group.

Pharmacodynamics and pharmacokinetics

Unidox Solutab is an antibiotic or not?

The active substance of the drug, doxycycline - is an antibiotic from the tetracycline group. It inhibits the vital activity of pathogenic bacteria, affecting the ribosomal membranes in the cell. It does not allow the processes of RNA synthesis of some organisms to occur.
The drug is active against such gram-positive bacteria as Streptococcus haemolyticus, Streptococcus viridans, Listeria spp, Streptococcus faecalis, Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis.
The drug inhibits the activity of Gram-negative bacteria: Bacillus anthracis, Neisseria meningitidis, Brucella spp., Escherichia coli, Neisseria gonorrhoeae, Haemophilus influence, Clostridium spp., Salmonella spp. , Pasteurella spp., Enterobacter spp., Entamoeba., Shigella spp. etc.
Also using doxycycline, the diseases caused by Mycoplasma spp., Rickettsia spp., Chlamydia spp. and Spirochaeta spp.
Doxycycline is absorbed into the digestive tract. Already after 2 hours after taking it, it can be found in virtually all tissues of the body (teeth, saliva), with the exception of cerebrospinal fluid. About half of the drug is excreted by the kidneys, the rest through the digestive tract. Detecting the blood plasma drug can be after 19 hours with a one-time admission and after 48 - during the course.

Indications for use

From what tablets Unidox Solutab?

The drug is prescribed for the treatment of diseases caused by microorganisms that are sensitive to doxycycline:
    ENT diseases (otitis, tonsillitis, etc.);
    diseases of the respiratory tract (pharyngitis, tracheitis, lung abscess, acute and chronic bronchitis);
    cystitis, prostatitis, pyelonephritis, urethritis, endometritis;
    IPP - with ureaplasma, syphilis, gonorrhea, chlamydia;
    infections of the gastrointestinal tract - cholera, cholecystitis, gastroenterocolitis, diarrhea, iersiniosis;
    trachoma, sepsis, peritonitis, osteomyelitis;
    prevention of malaria and postoperative diseases.

What else cures Unidox Solutab?

Jaundice, rickettsiosis, legionellosis, fever KU, typhus, Lyme disease in the first stage, spotted fever of the Rocky Mountains, tularemia, actinomycosis, plague, malaria, psittacosis, leptospirosis, ornithosis, bartonella, anthrax, pertussis, granulocyte erlichiosis, brucellosis, acne rashes.

Contraindications

    childhood;
    liver and kidney disease;
    pregnancy and lactation;
    porphyria;
    drug allergies to this group of antibiotics or substances in the formulation.

Side effects

    nausea, vomiting, loss of appetite, enterocolitis, inflammation in the genital area, due to the activation of Candida fungus growth, stomatitis;
    dermatitis, urticaria, anaphylaxis, pericarditis and erythema;
    renal and hepatic insufficiency, albuminuria, a lack of potassium in the blood, an increase in the level of nitrogen in the blood plasma;
    anemia, porphyria, thrombocytopenia;
    noise in the ears, hallucinations;
    brittle bones and teeth, discoloration of the enamel;
    hyperemia, anaphylactic shock, decreased blood pressure, tachycardia, shortness of breath.

Instructions for use Unidox Solutab (Method and dosage)

Duration of admission and dosage of the drug should be prescribed by a doctor, depending on the disease and its course. The tablets are swallowed whole or pulverized and mixed with water.
According to the instructions for Unidox Solutab, adults are prescribed 0.2 g of doxycycline per day (first day), for one or two doses. In the following days, the dosage can be reduced to 0.1 g, at the discretion of the treating physician.
With gonorrhea, syphilis and other serious ZPP, the daily dose, as a rule, is 0.3 g. The tablets are drunk for 5-10 days.
Children (from 8 years old), if their weight is less than 50 kilograms, the calculation is based on the principle of 0.04 g of antibiotic per 1 kg. Or twice less at the end of the first day of intake.

Overdose

Symptoms of overdose are nausea, headache, vomiting, diarrhea. Treatment - according to the manifested symptoms, gastric lavage, enterosorbents.

Interaction

Admission together with magnesium-containing laxatives, iron preparations, sodium hydrogen carbonate, calcium, magnesium and aluminum should occur at least 3 hours after the antibiotic.
The drug reduces the effectiveness of antibiotics of a number of penicillin and cephalosporin.
The drug can cause a decrease in the prothrombin index and the effectiveness of hormonal contraceptives. Also, with simultaneous administration with retinol, there may be an increase in intracranial pressure.
The concentration of doxycycline in the blood will decrease if you combine the drug with ethanol, rifampicin, phenytoin, barbiturates and carbamazepine.

Storage conditions

In a dark, cool place protected from children, the temperature regime is 15-25 degrees.
Shelf life - 5 years.

With alcohol

Unidox Solutab and alcohol it is better not to combine. When you take an antibiotic with alcohol, the concentration of the first in the blood plasma decreases, and the effectiveness of the drug decreases accordingly.

In pregnancy and lactation

The degree of penetration through the placenta and mixing with milk is too high. At pregnancy usually do not appoint or nominate.

Reviews of Unidox Solutab

Reviews in gynecology. The drug has good reviews in the treatment of gynecological diseases, for example from chlamydia. Patients to whom the drug was prescribed for chlamydia, note the easy tolerability of antibiotic and efficacy. Although sometimes there are side effects in the form of headaches and disruption of the digestive system.
Reviews when used from ureaplasma are also good, many hold opinions, the drug is almost the only effective way to get rid of the disease.
Reviews for Unidox Solutab for acne. Sometimes a dermatologist can prescribe antibiotics to treat acne. For most patients, the acne medication helps, but then there are other problems caused by the side effects of the drug. Many adherence to the therapeutic diet helped better than taking an antibiotic.