Amprilan tabs 10mg #30

Instruction for Amprilan

Reed more and buy Amprilan on this page

Composition

The active ingredient is ramipril. Additional substances: pregelatinized starch, lactose monohydrate, fumarate and sodium hydrogen carbonate, croscarmellose sodium. The composition of tablets with a dosage of 5 mg and 10 mg added a mixture of dyes.
Combined drug Amprilan ND additionally contains hydrochlorothiazide, which has a diuretic effect. Composition: 5 mg active ingredient of ramipril and 25 mg hydrochlorothiazide.
Combined drug Amprilan NL contains 2.5 mg of the active component of ramipril + 12.5 mg of diuretic hydrochlorothiazide.

Form of issue

The medicinal form is tableted. The drug is released in dosages of 1.25, 2.5, 5, 10 mg in blisters for 7 tablets. Blisters are packed in cardboard packs (3,6,9 pieces).

pharmachologic effect

The drug has vasodilating (dilates blood vessels), hypotensive effect. The active component belongs to the ACE inhibitor group.

Pharmacodynamics and pharmacokinetics

With ACE blocking, angiotensin-2 level decreases, renin activity increases, bradykinin action increases, aldosterone production increases. Hemodynamic and antihypertensive effects of the drug are provided by expanding the lumen of the vessel, reducing the OPSS. The medication does not affect the heart rhythm. Long-term treatment can lead to regression of left ventricular hypertrophy, which develops with arterial hypertension. Decrease in blood pressure is recorded 1-2 hours after taking the drug, the hypotensive effect persists for 24 hours.
In patients with heart failure, the risk of heart attacks, sudden death, progression of the disease, reduces the number of emergency hospitalizations and the number of hypertensive crises. In patients with diabetes mellitus, a decrease in microalbuminuria is observed, and the risk of nephropathy decreases. These effects develop independently of the level of blood pressure.

Indications for use Amprilan

    heart failure (chronic course);
    hypertonic disease;
    cardiac ischemia.
Indications for use in patients with diabetes mellitus: nephropathy.

Contraindications

    hypersensitivity to components;
    heart defects (mitral, aortic, combined);
    breast-feeding;
    cardiomyopathy;
    pathology of the renal system;
    hyperaldosteronism;
    pregnancy;
    age to 18 years.

Side effects

Most often, a sharp drop in blood pressure, syncopal conditions, migraine-like headaches, dry cough, bronchospasm, skin rash, exacerbation of gastritis and pancreatitis with an increase in the concentration of enzymes, pain in the joints and muscles.
Less common is arrhythmia, palpitations, angina pectoris complicated by myocardial infarction, Raynaud's syndrome, vasculitis, asthenia-depressive syndrome with sleep disorder, transient ischemic attacks and stroke, impotence, impaired renal function with increased creatinine and urea concentration in urine, allergic reactions, change laboratory indicators in the form of neutropenia, erythropenia.
With the progression of the severity of adverse reactions, it is recommended to consult a doctor and stop taking Amprilan for a while.

Amprilan, instructions for use (Method and dosage)

Ramipril is prescribed inside of the independence of eating. It is recommended to drink tablets with sufficient volume of liquid. The drug is prescribed by a doctor who selects an appropriate dose taking into account the patient's condition and the tolerability of the drug components. It is recommended to start taking Amprilan from small doses of 2.5 mg, with the possibility of increasing to the maximum of 10 mg. The duration of the drug is determined by the doctor, depending on the complaints and data, carefully collected anamnesis.
Instructions for use Amprilan ND and NL: 1 tablet per day. Possible dose adjustment during treatment. The duration of therapy is not limited.

Overdose

Symptoms of drug overdose are bradycardia (a rare pulse), a sharp drop in blood pressure, a shock condition with acute renal failure. To urgent measures in case of overdose include gastric lavage and timely use of enterosorbents, and with the threat of shock, the introduction of drugs that increase blood pressure.

Interaction

Vasopressor sympathomimetics, a group of non-steroidal anti-inflammatory drugs, corticosteroid hormones can reduce the severity of the hypotensive effect of raminipril. Strengthen the hypotensive effect of antipsychotics, antidepressant drugs. It is not recommended to combine Amprilan with preparations of the lithium group, gold, potassium-sparing diuretics, hypoglycemic agents, cytostatics, potassium preparations, immunosuppressants.

Terms of sale

You don't need a prescription to buy Amprilan online.

Storage conditions

At a temperature not higher than 25 degrees, in a place inaccessible to children.
Shelf life - 3 years.

Reviews about Amrilan (general view)

The drug has proved to be an effective tool in the therapy of heart failure of varying severity. Reviews of the tablets indicate a good tolerability of the drug and its high effectiveness in the treatment of hypertension.