Doxi-Chem caps 500mg #30
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Doxi-Chem user manualYou can buy Doxi-Chem on this pageCompositionIn 1 capsule of calcium dobezilate 521.51 mg.Form of issue Tablets 500 mg Capsules 500 mgpharmachologic effectAngioprotective.Ph..
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Doxi-Chem user manual
You can buy Doxi-Chem on this page
Composition
In 1 capsule of calcium dobezilate 521.51 mg.
Form of issue
Tablets 500 mg
Capsules 500 mg
pharmachologic effect
Angioprotective.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Angioprotector (capillary and venoprotector), affecting the vascular endothelium and normalizing metabolic processes in it. Under its action, vascular permeability normalizes, microcirculation improves, capillary stability increases, platelet aggregation and blood viscosity decrease, edematous syndrome and hemorrhagic diminishes. The effect of the drug is associated with an increase in kinin activity in plasma.
Pharmacokinetics
Slowly adsorbed from the digestive tract. After 5-6 hours in the blood the maximum concentration is determined, 20-25% of the substance binds to plasma proteins. It is excreted by the kidneys and intestines within 24 hours.
Indications for use
increased capillary permeability (with diabetic retinopathy and nephropathy);
varicose veins and venous insufficiency accompanied by pain, stagnant dermatosis, superficial phlebitis, trophic ulcers;
microangiopathy on the background of cardiovascular diseases.
Contraindications
exacerbation of peptic ulcer;
hemorrhage on the background of taking anticoagulants;
gastrointestinal bleeding;
kidney and liver diseases;
age up to 13 years;
I trimester of pregnancy;
hypersensitivity to the drug.
Side effects
nausea, diarrhea, vomiting;
itching, rash;
fever;
arthralgia;
reversible agranulocytosis.
Doxi-Chem, Instructions for Use (Method and Dosage)
Capsules or Doxi-Chem tablets are taken orally during meals. The average dose is 500 mg twice a day for 3 weeks, with a transition to 500 mg per day. With retinopathy appoint 500 mg three times a day for 4-5 months, with the transition to 500 mg per day. The drug is also prescribed for prophylactic purposes.
With fever, chills, pain when swallowing, inflammation of the oral mucosa (symptoms of agranulocytosis), you should consult a doctor.
Overdose
Not registered.
Interaction
Clinically significant drug interaction was not detected.
Terms of sale
To buy Doxi-Chem online the prescription is not required.
Storage conditions
Storage temperature 15-25 ° C.
Shelf life - 5 years.
Reviews about Doxi-Chem
Calcium dobezilate has a more pronounced effect on the permeability of blood vessels than etamzilate. It is the drug of choice for diabetic retinopathy, as a curative and preventive remedy, as evidenced by the reviews of patients. The drug is a highly effective angioprotector, which must be prescribed to patients with diabetes mellitus. As a result of treatment, retinal edema decreased and, in general, the prognosis improved with diabetic retinopathy. Side effects were very rare, the drug is easy to use and affordable.