Sydnopharm tabs 2mg #30

Instruction for Sydnopharm

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Composition

One tablet contains 2 mg of molsidomine + additional substances (wheat starch, colloidal silicon dioxide, lactose, mannitol, magnesium stearate, mint oil, microcrystalline cellulose, hydroxypropylmethylcellulose, E110).

Form of issue

The medicine is released in the form of round convex tablets of pink color, with a risk on one side. Tablets have a specific smell of mint. Packages of 30 pieces.

pharmachologic effect

Peripheral vasodilators.

Pharmacodynamics and pharmacokinetics

The active substance stimulates the process of increasing the concentration of cGMP, which, in turn, relaxes the smooth muscle cells of the vessels. Thus, preload and the body's need for oxygen decrease. There is an expansion of the vessels in the heart muscle. Circulation improves, cardiac stamina increases, and the number of attacks of angina decreases.
Blood clotting is reduced, due to the ability of molsidomine to suppress the early phase of platelet aggregation. If there is chronic heart failure, the drug has the ability to reduce the size of the heart cells, the stress in the myocardium, the amount of blood in the left ventricle.
After oral administration, the drug is absorbed after half an hour, with sublingual - after 10 minutes. The maximum effect of the drug reaches in half an hour - an hour, this state lasts for 6 hours. Metabolism undergoes in the liver, is excreted through the kidneys.

Indications for use Sydnopharm

The drug is prescribed for the prevention and treatment (cupping) of angina attacks:
    with chronic heart failure (in combination with other means);
    with acute left ventricular failure;
    with hypertrophy of the right ventricle on the basis of diseases that disrupt the normal functioning of the lungs;
    with increased pressure in the pulmonary circulation.
Also indications for Sydnopharm use are myocardial infarction (but only when the hemodynamic parameters stabilized).

Contraindications

The drug should not be taken:
    on the acute period (!) of myocardial infarction (especially against the background of low blood pressure);
    glaucoma;
    drug allergies to components;
    reduced pressure (below 100 Hg);
    cardiogenic shock;
    in old age;
    with vascular collapse;
    with toxic pulmonary edema;
    with circulatory disorders in the brain.
The medicine is not prescribed for pregnant and lactating women, in combination with Sildenafil, children under 18 years.
It should be very careful with a tendency to lowered pressure, after suffering a hemorrhagic stroke.

Side effects

There is a high probability of lowering blood pressure, the appearance of tachycardia, redness of the face, the onset of vascular collapse, nausea, anorexia, general weakness. Perhaps the manifestation of allergic reactions.
Sometimes at the beginning of treatment, headache, dizziness, nausea and vomiting may occur, but after a while these effects go away.

Sydnopharm, instructions for use (Method and dosage)

Tablets are taken orally or sublingually (if necessary) during meals or after meals.
The regimen and dosage should be prescribed by the doctor, depending on the frequency of attacks and the nature of the course of the disease. Duration of admission should also be determined by the attending physician.
According to the instructions for use Sydnopharm, the maximum daily dosage is 12 mg of the drug. As prevention, prescribe, the first few days, half or the whole tablet four to six times a day. Further, the daily dosage can be increased to 8 mg, distributing it for 2-3 doses.
In the acute course of the disease, as a rule, the dosage is increased to 4 tablets, for 3-4 doses.

Overdose

Symptoms of overdose are: severe headache, bradycardia, hypotension, nausea, possible collapse.
As a treatment, gastric lavage, reception of enterosorbents, diuresis, elimination of overdose symptoms are performed.
Data on the effectiveness of dialysis in case of an overdose are few.

Interaction

The medicine is strictly forbidden to combine with alcohol.
Vasodilator, antihypertensive drugs, increase the likelihood of collapse and a critical decrease in blood pressure,
Acetylsalicylic acid in combination with Sydnopharm has a more pronounced anti-aggregative effect.
It is not recommended to combine the medicine with Sildenafil.

Terms of sale

To buy Sydnopharm you don't need a prescription.

Storage conditions

Store in a dry, cool place (no higher than 25 Degrees), away from children.
Shelf life - 3 years.

Reviews about Sydnopharm

The drug has different reviews. Many drugs help, overall health improves, the frequency of occurrence of atrial fibrillation decreases against the background of physical exertion. For some, the effect of the funds is insufficient, and they switch to receiving other funds. In any case, the question of discontinuing or changing the drug should be resolved with the attending physician, all strictly individual.
Often at the beginning of taking the remedy there are headaches and nausea, but after a week this effect passes.