Trombo ACC 100mg #100

Trombo ACC instruction for use

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The drug Trombo ACC belongs to the group of non-steroidal anti-inflammatory drugs and has a pronounced analgesic, antipyretic and antiplatelet effect.

Form of release and medicinal composition

Trombo ACC is available in the form of tablets for oral use, film-coated enteric-coated. Tablets of white color, round, convex on both sides, packed in blisters of 14 pieces (2) in a cardboard bundle, an abstract with a detailed description of characteristics is attached to the preparation.
Each tablet contains 50 mg or 100 mg of active ingredient - Acetylsalicylic acid, as auxiliary components are lactose monohydrate, microcrystalline cellulose, silicon dioxide, potato starch.

Indications for use

Tablets Trombo ACC are prescribed to patients as the main agent or as part of complex therapy for the treatment and prevention of the following conditions:
    prevention of acute myocardial infarction (primary) for patients at risk - those with diabetes mellitus, hypercholesterolemia, hypertension, obesity;
    treatment and prevention of angina attacks;
    prevention of ischemic stroke with blockage of lumens of large blood vessels by atherosclerotic plaques;
    prevention of cerebral circulation disorders by ischemic type;
    prevention of deep vein thrombosis;
    prophylaxis of thromboembolism after surgical interventions on vessels (coronary artery bypass grafting, stent placement in coronary arteries, angioplasty).

Contraindications

The drug can not be started on its own, relying on their own feelings and well-being. The Trombo ACC tablets have a number of contraindications:
    gastrointestinal bleeding or suspicion of them;
    peptic ulcer of stomach and duodenum in the phase of exacerbation or in anamnesis;
    hemorrhagic diathesis;
    The bronchial asthma, which appeared on the background of therapy with acetylsalicylic acid or other drugs from the group of NSAIDs;
    diseases of the liver and kidneys, accompanied by a violation of the function of organs;
    simultaneous therapy with methotrexate;
    chronic heart failure;
    pregnancy in 1 and 3 trimesters;
    the period of breastfeeding;
    age to 18 years;
    lactose intolerance, glucose malabsorption syndrome;
    polyposis of nasal sinuses.
Relative contraindications for the use of the drug are:
    gout;
    hyperuricemia;
    mild renal insufficiency;
    allergy to medicines;
    2 trimester of pregnancy;
    preparation for surgery, including dental;
    hay fever;
    an erosive gastritis in the anamnesis.

Dosing and Administration

Tablets Trombo ACC should be taken after a meal or during a meal, squeezed with a large amount of water, without cracking or chopping. The drug is intended for long-term use, but the doctor determines the dose and duration of the course of treatment, depending on the patient's condition and the characteristics of his body.
To prevent infarction and thrombosis, the daily dose of the drug is 50 mg, if necessary, it can be increased to 100 mg per day under the supervision of a doctor.
For the prevention and treatment of pulmonary embolism and deep vein thrombosis, 100 to 200 mg of drug per day are administered, divided into 2 doses.

Use of the drug during pregnancy and lactation

In the first trimester of pregnancy, the preparation of Trombo ACC is not prescribed, since all the organs and systems of a future child are laid on this term, and the effect of drugs on the female body can disrupt this process and cause the formation of congenital anomalies.
In the second trimester of pregnancy, the use of the drug is possible under the supervision of the doctor, in the event that the expected therapeutic effect for the mother significantly exceeds the probable risks to the child.
In the third trimester of pregnancy, the use of Trombo ACC tablets is contraindicated, since treatment can lead to internal bleeding in the fetus, massive birth defects and bleeding disorders in the newborn.
Acetylsalicylic acid can be excreted in breast milk and cause severe side effects in infants, so treatment with the drug is not performed during lactation. If necessary, breastfeeding should be discontinued.

Side effects

During the reception of Trombo ACC tablets in patients with increased individual sensitivity to acetylsalicylic acid, side effects may develop:
    on the part of the digestive system - heartburn, stomach pain, nausea, exacerbation of chronic gastritis and ulcers, vomiting, intestinal bleeding, development of reactive pancreatitis, increased activity of liver transaminases;
    from the nervous system - dizziness and headaches, tinnitus, hearing loss;
    risk of bleeding, hematoma, bleeding gums;
    on the part of the blood picture - thrombocytopenia, anemia, a decrease in the color index and the level of erythrocytes in the blood;
    allergic reactions - rash on the skin according to the erythematous type, minor hemorrhages under the skin, Quincke's edema, bronchospasm, development of bronchial asthma, rhinitis, in rare cases development of anaphylactic shock.
If one or more side effects appear, the drug should be discontinued and consult a doctor.

Overdose

When ingesting Trombo ACC tablets in large doses, the symptoms of overdose develop rapidly, which are expressed in acute salicylate poisoning - vomiting, feces with blood, toxic liver damage, nosebleeds, tinnitus, respiratory alkalosis.
In severe poisoning with acetylsalicylic acid, patients develop pulmonary edema, respiratory depression, asphyxia (choking), cardiac arrhythmias, convulsions, coma.
Treatment of an overdose of salicylates is to wash the stomach, multiple intake of activated charcoal, restore the water-salt balance, if necessary, carry out symptomatic treatment.

Drug Interactions

Special care requires the drug interaction of Trombo ACC tablets with such drugs:
    Methotrexate;
    Anticoagulants - because of the risk of massive bleeding;
    NEP;
    Thrombolytic agents;
    Hypoglycemic drugs and insulin.
The acetylsalicylic acid, which is part of the Trombo ACC tablets, enhances the therapeutic effect of the aforementioned drugs, which increases the likelihood of side effects and overdose. If a drug interaction is required, dosage adjustment is required.
With the simultaneous administration of tablets with drugs from the group of glucocorticosteroids, a decrease in the therapeutic effect of acetylsalicylic acid is observed.

special instructions

Tablets Trombo ACC can only be taken as prescribed by a doctor after preliminary blood testing.
Acetylsalicylic acid, which is part of the drug, can cause the development of bronchospasm in people prone to allergies or patients suffering from bronchial asthma. Asthma attacks on the background of therapy with the drug are becoming more frequent and more severe.
In the presence of a history of urticaria, edema of the nose and pharynx after taking tablets of Acetylsalicylic acid or NVPV before treatment with the drug Trombo ACC should always consult a doctor.
Against the background of drug treatment, the patient's platelets in the blood are reduced, which can lead to bleeding during the operation. If the patient has planned surgery, including tooth extraction, it is necessary to warn the doctor that he was taking Trombo ACC.
Women taking the pill of the drug should be carefully protected from the onset of an unplanned pregnancy, and if the conception occurs, the drug is immediately stopped and consulted by a doctor.
Tablets Trombo ACC can not be taken concomitantly with acetylsalicylic acid or non-steroidal anti-inflammatory drugs, as this increases the risk of side effects and severe overdose.
Patients over 65 years of age require an individual dose selection, since in this age group, the risk of side effects is particularly high.
At occurrence of unpleasant sensations in the field of an epigastrium against a background of treatment by a preparation, a nausea, a cut in a stomach reception of tablets immediately stop and address to the doctor.
During treatment, the drug should refrain from activities that require increased concentration and control of the car. This is due to the appearance of dizziness and noise in the ears on the background of therapy.

Analogues of Trombo ACC tablets

A similar therapeutic effect with Trombo ACC tablets is the following:
    Aspirin cardio tablets;
    Acetylsalicylic acid tablets.
All these drugs have serious contraindications, so you can not independently begin treatment without consulting a doctor.

Leave and storage conditions

Tablets Trombo ACC are sold without a prescription from pharmacies. Tablets should be stored in a dry place, at a temperature of no higher than 25 degrees. Shelf life of the tablets is 3 years from the date of production, at the end of this period the tablets should be discarded.