Marvelon tabs #21

Instruction for Marvelon contraceptive pills

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Marvelon refers to monophasic contraceptives in oral form.

Composition, form of release

The medicament is produced in the form of white tablets having a round biconvex shape. On one side of the tablet there is an engraving "TR" and a number "5", and on the other side - "ORGANON" and a star-shaped drawing with five ends.
Each tablet contains 30 μg of active substance in the form of ethinylestradiol and 150 μg of desogestrel.
As additional compounds, lactose monohydrate, colloidal silicon dioxide, povidone, alpha-tocopherol, stearic acid and potato starch are used.

Pharmacological properties

The drug belongs to the class of hormonal contraceptive pharmaceuticals.
Thanks to such components as desogestrel and ethinyl estradiol, as a result of the use of the drug there is no occurrence of an unplanned pregnancy.
Also, the drug has a number of other positive effects:
    Reduces the risk of cancer;
    It is a prophylactic means of ectopic pregnancy;
    Prevents inflammatory diseases in the small pelvis;
    Prevents development of cystic formations;
    Reduces the likelihood of fibrocystic disease;
    Reduces the likelihood of anemia, which is associated with a lack of iron in the body;
    The amount of bleeding during menstruation is significantly reduced;
    The process of menstruation becomes more regular with less pronounced painful sensations.

Indications for use

Marvelon is prescribed as a contraceptive drug.

Dosing regimen

The medication is for internal use only. Tablets should be taken at the same time of day.
Each course takes 21 days. The next appointment should be made one week after the end of the previous course. During this period of time, the patient should have menstruation.
If a woman first uses this medication, then taking the pill is necessary on the first day of menstrual bleeding.
After having had an abortion in the first trimester of pregnancy, it is recommended to start taking pills immediately. Additional contraception can not be used.
After the childbirth and after the abortion, which was made in the 2nd trimester of pregnancy, the reception should be started after 21 or 28 days. If the drug was taken at a later date, additional contraceptive methods should be used during the first week of admission.
If during the administration of the medicine there were severe disorders in the digestive tract, then the assimilation of the medication may be inadequate. In this regard, the patient should use additional methods of contraception. In a situation where vomiting occurred within 3-4 hours after using the pill, you need to act according to the recommendations for skipping the next use of the medication. If the patient does not want to change the usual pattern of use, then take 1 more tablets from the next package (the number of tablets that need to be taken in addition determines the gynecologist).
If the patient has forgotten to take the next pill for less than 12 hours, then the safety of contraception does not go down. A woman should drink a pill right away, as soon as she remembers it, and the following techniques should be performed at the usual time.
In a situation where the intake of tablets is delayed more than 12 hours, the safety of contraception is reduced. When a pass occurs in the first week of the course of taking Marvelon, the patient needs to drink the pill right away when she remembers. Further reception continues according to the usual pattern, but barrier barriers are additionally used.
If as a result of missing the medication, there was no menstrual cycle, this could be a sign of pregnancy. In this regard, before starting a new course, you need to make sure that it is not available.
If you need to push the time of the beginning of menstruation, the medicine should be continued without taking a usual seven-day break between the courses.

Overdose

If the drug is used in a dosage exceeding the therapeutic limit, symptoms such as vomiting and nausea may appear. In young patients, discharge with blood from the vagina was observed. Serious side effects from overdose were not observed.
In the case of an overdose, treatment is performed aimed at suppressing undesirable symptoms. This drug has no antidotes.

Drug Interactions

The contraceptive effect of Marvelon is inhibited, and the risk of the occurrence of profuse vaginal bleeding increases with parallel administration of the following medications:
    Felbamate;
    Primidone;
    Isoniazid;
    Carbamazepine;
    Rifampicin;
    Barbiturates;
    Oxcarbamazepine;
    Topiramate;
    Griseuwulfin;
    Derivatives of hydantoin.
Also, the contraceptive effect of Marvelon's drug is reduced when combined with antibiotics that belong to a series of penicillins, tetracyclines, with the simultaneous administration of chloramphenicol, neomycin, charcoal of activated and laxative medicines.
Marvelon drug lowers the therapeutic effect of the following drugs:
    Glucocorticosteroids;
    Antidiabetic medications;
    Caffeine;
    Anxiolytics;
    Clofibrate;
    Theophylline;
    Antidepressants tricyclic;
    Coagulants for oral administration.

Lactation, pregnancy

The drug Marvelon can not be administered to patients during lactation and pregnancy. If the pregnancy occurred during therapy, then the use of the medicine should be canceled.
The drug affects the lactation process, reducing the amount of produced breast milk and changing its composition. In this regard, it is not recommended to prescribe this drug until the complete cessation of breastfeeding.

Side effects

The use of a medicament may provoke the following undesirable manifestations:
    Cardiovascular system: increased blood pressure, thromboembolism or thrombosis (stroke, myocardial infarction, pulmonary artery thromboembolism, thromboembolism of renal, mesenteric, hepatic veins and arteries, and arteries in the retina);
    Skin: Chloasma (more likely to occur if there is a chloasma in the patient's history during pregnancy);
    Digestive system: cholelithiasis, pruritus or acute jaundice associated with cholestasis; colitis ulcer, Crohn's disease;
    Cardiovascular system: increased blood pressure, thromboembolism, thrombosis.
    High susceptibility to any component of the drug;
    Lack of lactase;
    Increased amount of triglycerides in the blood;
    Migraine, accompanied by a neurologic deficit in focal form;
    Lactation;
    Bleeding from the vagina of an unclear cause;
    Pregnancy;
    The presence of hormone-dependent malignant tumors in the mammary glands or genitals;
    Diseases of the liver in severe stages;
    Malignant or benign neoplasms in the liver;
    The presence or increased risk of thrombosis of the arteries or veins;
    Diabetes mellitus with the presence of affected vessels.

Contraindications

Medication can not be administered in the following situations:

special instructions

As a result of the research, it was found that taking a medication can increase the risk of venous and arterial thromboembolic and thrombotic diseases (pulmonary artery thromboembolism, stroke, myocardial infarction).
If as a result of treatment with the drug, the number of migraine attacks increases, then this is the basis for the complete withdrawal of the drug.
Before starting treatment with Marvelon, a specialist should know the detailed medical information about the patient, prescribe the necessary examination and take into account all warnings and contraindications. During the period of application of the drug, these procedures should be repeated periodically. This should be done in order to identify diseases or probable risks that first appeared on the background of therapy, which may be a contraindication to the use of the drug. Increased attention should be paid to measuring blood pressure, examining the mammary glands, as well as genitals.
The patient should be aware that the use of this medication is not a protection against AIDS and other infections that can be transmitted as a result of sexual intercourse.
The therapeutic efficacy of the drug may decrease in the situation of skipping the use of the medication, in disorders of the digestive tract, or in the parallel administration of certain medications.
At the beginning of therapy, the patient may have either significant blood discharge, or unpronounced and spotting discharge. The first 3 months are considered an adaptation period, so only after this time you can make an assessment of bleeding.
If irregular discharges are preserved or have arisen after the restoration of the regular cycle, then it is necessary to take into account probable non-hormonal causes. It is recommended to do the necessary studies in order to exclude pregnancy or the presence of malignant tumors.
Contraceptives in oral form affect laboratory indicators (transport proteins, functional parameters of the kidneys, adrenals, thyroid gland, liver).
The drug does not affect the ability of the patient to drive vehicles and work with complex mechanisms.

Terms and conditions of storage

The drug is stored at a temperature of 2 to 30 g C in a dry and dark place, distant from small children. The medicine is allowed to be used within 3 years from the moment of its release.