Xamiol gel 15gr

Instruction for Xamiol

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Composition

In 1 g of gel, 0.5 mg of betamethasone and 50 μg of calcipotriol. Castor oil, mineral, polyoxypropylene-15-stearyl ether, as auxiliary components.

Form of issue

Gel in bottles of 15, 30 and 60 g.

pharmachologic effect

Anti-inflammatory, antipruritic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Xamiol is a combined preparation intended for topical treatment of psoriasis of the scalp. Successfully used in the treatment of other localizations.
Calcipotriol is a synthetic analogue of vitamin D and inhibits the proliferation of keratinocytes. Glucocorticosteroid Betamethasone has antipruritic, anti-inflammatory, immunosuppressive effect, which is enhanced with the use of occlusive dressings. The gel is odorless, does not contain ethyl alcohol and is quickly absorbed.

Pharmacokinetics

Absorption of active substances through intact skin is insignificant - 1%. When used under occlusive dressings, it increases significantly. With daily use in the skin creates a depot of active substances, the elimination of which occurs within a few days. Metabolized betamethasone in the liver and kidneys, is excreted with feces and urine.

Indications for use

As part of complex therapy, Xamiol gel is used in the treatment of psoriasis of the scalp and other parts of the body. Effective for mild to moderate severity of the disease.

Contraindications

    hypersensitivity;
    age to 18 years;
    severe renal and hepatic insufficiency;
    a violation of calcium metabolism;
    bacterial, viral and fungal skin diseases;
    rosacea;
    rosacea;
    perioral dermatitis;
    skin atrophy;
    psoriatic erythroderma;
    pustular psoriasis.

Side effects

Local reactions:
    itching;
    irritation, burning, rash, exacerbation of psoriasis;
    dry skin, folliculitis, acne;
    atrophy of the skin, striae, perioral dermatitis, hypertrichosis (with prolonged use).
Systemic reactions occur when applied to occlusal dressings, as well as long-term treatment of large areas of the skin.
    hypercalcemia or hypercalciuria;
    oppression of the adrenal cortex;
    increased intraocular pressure.

Gel Xamiol, instructions for use (Method and dosage)

Before use, the vial should be shaken. The gel is applied to the affected areas or psoriatic plaques once a day. To treat lesions on the scalp, it is enough 1-4 grams per day (approximately 1 teaspoon - 4 g).
The maximum daily dose is up to 15 g. The drug is left on the skin for the night without washing off.
The average duration of the course is 1 month (on the scalp), with lesions of other parts of the body - up to 2 months.
Do not use on mucous membranes. In case of accidental ingestion, reactions appear in the form of irritation and conjunctivitis. Be careful when using the face and genitals on the skin. After applying the gel, you should wash your hands.
The drug is canceled gradually, since the sudden cessation of treatment is sometimes associated with the emergence of the effect of withdrawal and the development of common pustular psoriasis. During treatment, it is necessary to limit exposure to sunlight.

Overdose

Overdose manifests itself by suppressing the function of the adrenal cortex and increasing the level of calcium in the blood. These phenomena are reversible when the drug is discontinued, which is gradually canceled. If necessary, symptomatic therapy is performed.

Storage conditions

Temperature up to 25 ° С. Outside the fridge.

Shelf life

2 years. The period after opening the bottle is 6 months.

Reviews of Xamiol

The most active means of treatment of psoriasis with exacerbation are modern topical steroids, among which it should be noted betamethasone. The leading direction in the treatment is given by the vitamin D derivative. The effectiveness of this drug, which combines two active substances, has been proven in many studies and is confirmed by patient reviews. After 2 weeks of treatment there is a significant improvement in 60% of patients, and in two months recovery in 70% of patients is noted. It is important to significantly reduce the index of PASI (index of severity and prevalence of psoriasis) a month from the start of treatment by 69.9%.
In general, it can be noted that the drug is characterized by high efficiency, safety, is available on an outpatient basis. Reviews of the gel Xamiol for psoriasis are positive and many, based on their experience, advise it. It is also noted that with proper use of side effects does not occur.
    "... I have been using it for a long time and successfully. Of course I follow all the recommendations for nutrition, health improvement of the digestive tract. Do not be afraid of any complications. "
    "... Of course it helps. It's a steroid drug. Stronger can not imagine. I was helped very much. It simply needs to be used for the intended purpose and the course prescribed by the doctor, then there will be no complications. "
    "... I put on my scalp with a cotton bud - less consumption and tidy."
    "... Helps to quickly remove inflammation and itching, so I'm assigned to relieve a severe exacerbation. Then I always turn to maintenance treatment with hormonal ointments. "
    "... I have psoriasis on my head, and the drug is suitable for this part. This is the only remedy that helps me a lot. "
    "... I smear the plaques with this gel. I need 2-3 weeks for everything to go away. "
    "... I really helped. I liked that he quickly absorbed.
    "... With the help of treatment with this gel I managed to reduce the number of exacerbations up to 1 time per year."
    "... Assigned as a" starter "remedy, and for a short time, then transferred to pure calcipotriol (Daivonex), which was also gradually canceled. The effect is very good. "