Calcium Sandoz Forte tabs 500mg #20

Calcium Sandoz Forte user manual

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Composition

In 1 tablet of lactogluconate calcium 1132 mg or 2263 mg, calcium carbonate 875 mg or 1750 mg.
Citric acid, butyl hydroxy anisole, macrogol 6000, aspartame, sodium hydrogen carbonate, flavoring as auxiliary substances.

Form of issue

Tablets are soluble 500 mg and 1000 mg.

pharmachologic effect

Replenishment of calcium deficiency.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Calcium is an important element that is necessary for the regulation of many processes in the body, maintaining the equilibrium of electrolytes and participating in phosphate-calcium metabolism. This drug replenishes its deficiency under various conditions, and is prescribed for metabolic disorders in bone tissue. Has anti-cancer and anti-allergic effect.
The drug in its composition has two calcium salts, which in the form of effervescent tablets dissolve quickly, turning into an active form. Such a dosage form provides easy absorption and calcium intake into the body.

Pharmacokinetics

About 25-50% of ionized calcium is absorbed in the small intestine and enters calcium stores. The largest number (99%) is found in bones and teeth, in the extracellular fluid is 1%. About 50% of total calcium in the blood is in active ionized form, 5% in the form of anionic complexes, and 45% is associated with proteins. Approximately 20% is excreted by the kidneys with urine and 80% with feces. The degree of excretion by the kidneys depends on the glomerular filtration.

Indications for use

    osteoporosis in postmenopause;
    drug osteoporosis;
    insufficiency in the diet;
    osteomalacia (in combination with vitamin D3);
    allergic reactions;
    increased need (with pregnancy, breast-feeding, period of intensive growth);
    latent flow of tetany.

Contraindications

    chronic renal failure;
    hypercalcemia, hypercalciuria;
    hypersensitivity to the drug;
    urolithiasis, nephrocalcinosis;
    phenylketonuria, intolerance to fructose;
    age up to 3 years.

Side effects

Very rarely Calcium Sandoz Forte can cause:
    rash, swelling of the face, itching, hives, angioedema;
    hypercalcemia, hypercalciuria;
    flatulence, constipation, vomiting, diarrhea, nausea, epigastric pain.
When taking 2000 mg per day for several months, there is headache, thirst, fatigue, polyuria.

Instructions for use (Method and dosage)

The tablet is dissolved in water and taken internally, regardless of the time of ingestion. Adults prescribe 1000 mg / day. With increased need, the dose is increased to 2000 mg / day. Children from 3 years of age 500 mg / day, and from the age of 10 is prescribed a dose of adults.
Duration of treatment is 4-6 weeks. For prevention and treatment of osteoporosis, the duration of reception is determined individually.
In pregnancy, the daily dose is not more than 1500 mg. In patients with impaired renal function and with the presence of urolithiasis, continuous monitoring of calcium in the urine is necessary.

Overdose

Overdose Calcium Sandoz Forte manifests symptoms of hypercalcemia: nausea, vomiting, polyuria, thirst, polydipsia, dehydration, constipation. When taking more than 2000 mg / day for several months, a chronic overdose appears, which can lead to liming of the vessels.
Treatment: restoration of water-electrolyte balance - hydration is carried out. With the aim of increasing the excretion of the drug loop diuretics (Furosemide) are used, thiazide diuretics are not prescribed. Patients with renal insufficiency are shown dialysis.

Interaction

In connection with the formation of nonabsorbable complexes, the drug can reduce the absorption of the cytostatic estramustine, etidronate bisphosphonate, phenytoin, fluoride preparations, tetracyclines, quinolones. Therefore, the interval between taking these drugs and effervescent tablets should be 3 hours or more.
Co-administration with vitamin D increases calcium absorption, which reduces the action of Verapamil.
Thiazide diuretics reduce the excretion of the drug in the urine, and there is a risk of hypercalcemia, so with the simultaneous administration of these diuretics you need to monitor the calcium content in the blood.
Corticosteroids reduce its absorption, so it may be necessary to increase the dose.
In connection with the development of hypercalcemia with simultaneous administration of cardiac glycosides, their toxicity increases. The ECG should be monitored regularly.
Absorption of the drug from the digestive tract decreases with the use of spinach, rhubarb (oxalic acid) or cereals containing phytic acid, since insoluble complexes are formed. In this case, effervescent tablets should be taken 2 hours before taking this food.

Storage conditions

At a temperature not exceeding 30 ° C.
Shelf life - 3 years.

Reviews of Calcium Sandoz Forte

Recall that the daily rate of calcium increases with age and is 1000-1500 mg / day, and does not matter the source of its receipt - food or medicines. If the diet contains 1000 mg, then only 200-300 mg is included in the metabolism. Most of this element contains dairy products, and it is absorbed almost completely. In green vegetables and cereals it is in the form of insoluble salts (oxalates and phosphates), the absorption of which is much lower.
The drug is prescribed in those cases when there is an increased need for calcium (pregnancy, increased growth of the child), with diabetic osteoarthropathy, rickets, allergic dermatitis.
Calcium Sandoz Forte is also prescribed to improve fracture fusion and prevent osteoporosis. The doctors' comments testify to the effectiveness of this drug for various pathologies of bone tissue. Employees of the Department of Traumatology and Orthopedics of the Belarusian State Medical University in Ufa published the results of the use of this drug in complex treatment (with vitamin D and bisphosphonates) of juvenile osteoporosis in children. It is noted that the composition of the drug includes rapidly dissolving ionized salts (lactogluconate and carbonate), which have high bioavailability, that is, they are well absorbed, which can not be said for calcium gluconate. However, calcium carbonate reduces the acidity of gastric juice. Calcium Sandoz Forte is approved for use in children from the age of 3 years, which expands the possibilities of its use. For example, Natekal D3 and Calcemin Advance can be used in children only from the age of 12. The drug is better to take in the evening, because at this time there is a maximum absorption (after 19 hours).
At the Department of Gynecology of the Minsk Medical Institute, developing methods of correcting osteoporosis, once again proved that the role of calcium metabolism disorders in the onset of osteoporosis is undeniable, but its preparations and vitamin D are not basic in treatment. The basis for the prevention and treatment of osteoporosis is hormone replacement therapy (estrogens and gestagens in various combinations). And calcium preparations, bisphosphonates, vitamin D, calcitonin and fluorides are used in the complex treatment of this disease. It should be borne in mind that drugs containing highly digestible salts will be effective in this disease.
Analyzing reviews about Calcium Sandoz Forte you can make a conclusion about the effectiveness of the drug. Users note the availability of it in the pharmacy network, a convenient form of release - water-soluble tablets.
"Tablets of other manufacturers could not swallow because of the large size. And these are a pleasure "
"I think that I kept my teeth during pregnancy and feeding the child only thanks to these pills. Reviews only positive »
"The hair began to fall out and the nails would break down. She drank 20 tablets, felt improvements from her hair and nails "
According to the reviews, the drug is well tolerated, only some people have noted pain in the stomach and constipation with prolonged use.