Succinic acid 100mg #10

Succinic acid instruction for use

You can buy Succinic acid online

Composition

The tablets Amber acid Mosbiopharm include 100 mg of succinic acid, as well as potato starch, sugar, calcium stearate, talc, aerosil.
Tablets produced by Elit-Pharm contain 150 mg of amber and 10 mg of ascorbic acid.

Form of issue

The additive is available in tablets of 0.1 and 0.25 g in packages No. 40, No. 80 and No. 100 of the tablets in the package.

pharmachologic effect

Antihypoxic, metabolic, antioxidant.

Pharmacodynamics and pharmacokinetics

Succinic acid (YAK) is an intracellular metabolite of the citrate cycle (Krebs cycle). In the cells of the body performs a universal energy-synthesis function.
With the participation of coenzyme FAD (flavinadenine dinucleotide) and under the influence of succinate dehydrogenase (mitochondrial enzyme of the class of oxidoreductases), it is rapidly biotransformed into fumaric acid and later into other products of the Krebs cycle metabolism (the end products of the metabolism of YAK are carbon dioxide and water).
Stimulates the breakdown of glucose through the aerobic pathway and the synthesis of ATP, which plays an important role in the energy metabolism in the body; due to activation of electronic transport in mitochondria improves tissue respiration.
The substance possesses strong antioxidant properties of directed mitochondrial action, which promotes organism rejuvenation at the cellular level.
Widespread use in medicine is due to the ability to stimulate the compensatory-protective and adaptive capabilities of the body; increase the formation of hydrochloric acid and the secretory function of the glands of the stomach, improve appetite and contractile function of smooth and striated muscles, increase diastolic blood pressure and physical performance.
In addition, by activating intracellular metabolism and cellular respiration, YAK promotes the excretion of poisonous substances from the body and reduces the toxic effect of alcohol.
When ingested, the YAK penetrates from the digestive tract into tissues and blood, takes part in catabolic reactions and within half an hour is completely cleaved to the final products of metabolism. The substance does not accumulate in the body. T1 / 2 - about 26 minutes.

Indications for use: from what tablets of succinic acid?

The use of succinic acid in tablets is shown as a dietary supplement of succinic acid.
The agent is prescribed for functional asthenic conditions. Especially its effect is manifested with age-related ailments and in extreme conditions (including in conditions of oxygen starvation).
The preparations of succinic acid help reduce the manifestations of sclerotic changes (forgetfulness, increased fatigue, etc.) and effectively relieve the headache caused by a disturbance in the nutrition of brain cells.
These properties of YAK make it expedient to use it for ischemic conditions, muscle contractures (muscle stiffness), vasospasm.
Doctors recommend the introduction of drugs YAK as an addition to the main therapy for diseases of the heart and blood vessels. Indications for the use of additives are including: atherosclerotic lesions of the vessels of the lower limbs, IHD.
With all these diseases, the patient is forced to take a large number of drugs for a long time (sometimes for life): normalizing the heart rhythm, anti-sclerotic, antihypertensive, anticoagulant, vasodilating, potassium-containing, maintaining the cholesterol balance, diuretics.
Introduction to the treatment regimens of YaK allows to significantly reduce both the number of medications taken and the duration of their administration. The effect is achieved due to pharmacological properties of YaK and due to its ability to enhance the effectiveness of the drugs of basic therapy.
Application of Succinic acid in a dose of up to 1 g / day. provides a distinct potassium-preserving and diuretic effect, which contributes to an increase in daily diuresis and a rapid decrease in edema in patients with various diseases of the circulatory system (rheumatic diseases, IHD, etc.), and also significantly reduces the dose of cardiac glycosides and diuretics.
The results of the studies are confirmed by the dynamics of the ECG. All patients taking part in the experiment after the course of the use of YaK preparations improved blood circulation in the coronary vessels, the heart rate normalized, the blood levels of the PTI and cholesterol in the blood decreased, and the fraction of β-lipoproteins was normalized.
A positive effect is noted in the case of the use of drugs of YaK in combination with agents for the treatment of discirculatory encephalopathy and cerebral atherosclerosis.
Moreover, it becomes noticeable after 3-5 days, and after 2-2.5 months, the manifestations of sclerotic symptoms significantly decrease in patients: dizzinesses decrease, as well as intensity and frequency of headaches; memory, mood and sleep are improved; increased concentration of attention.
In diseases of the musculoskeletal system (for example, with deforming osteoarthritis or osteochondrosis) in patients taking YaK, soreness, swelling and joint deformity decrease, their mobility increases and, in addition, the concentration of uric acid in the blood decreases.
Studies of supplement use in patients with bronchopulmonary pathologies have shown that the appointment of a patient of 0.5 to 1.5 grams of YA per day can improve overall well-being and prolong the period of remission. Changes are noted in the indicators of the state of the immune status, both in the cellular and humoral segments.
The prophylactic use of YaK preparations with a 2-3-week course during periods of seasonal exacerbations of chronic diseases makes it possible to achieve that even if the patient does become ill, the disease proceeds in a lighter form, and recovery is much faster.
The admission of high doses of YaK during the acute respiratory viral infection and influenza prevents the development of the disease and allows you to restore your ability to work within a few days.
Succinates regulate the production of insulin, which helps restore the metabolism of saccharides. This property allows the use of YaK for the prevention and treatment of non-insulin-dependent diabetes.
The increase in insulin secretion is due to the fact that the YaK activates enzymes independent of the dextrose level in the body.
Succinic acid prevents genetic disorders, which are a consequence of the influence of carcinogenic substances and lead to uncontrolled cell division. The use of additives with succinates can reduce the death rate of cancer patients several times and improve their quality of life.
It has been experimentally proved that succinates suppress the growth of neoplasms. Accumulating mainly at the site of tumor formation, the YaK prevents the reproduction of malignant cells.
In addition, the drug helps reduce the severity of side effects of chemotherapy: the decline of strength, depression, nausea.
The positive effect of the use of YaK is most pronounced in myoma, mastopathy, cysts and other benign tumors.
Separate attention deserves the use of YaK in gerontological patients, who in the overwhelming case have a complex pathology.
Benefits for the body of an elderly person is that the use of Ya tablets can reduce the severity of symptoms of age-related diseases and, at the same time, reduce the amount and dose of pharmacological preparations they need.
The greatest effectiveness is observed with the use of YA in combination and with the means that restore the intestinal microflora. This combination promotes an increase in the immune status, while in patients there is a clear tendency to normalize the serum concentration of malonic dialdehyde and the expression of endogenous intoxication decreases.
For preventive purposes, YaK can also be taken by healthy people. The introduction of supplementation in the diet of athletes makes it easier to adapt to the constantly increasing loads and to stop pain in the muscles after intensive training.
Also, the remedy is used for intoxications of various etiologies (including alcohol and drug).
Cosmetologists recommend the use of YaK for hair and skin.

Contraindications to buy succinic acid

Succinates are natural substances for the human body, so even with prolonged admission, they do not cause side effects and addictions.
Nevertheless, the preparations of YaK have contraindications. Tablets are not prescribed for:
    peptic ulcer during its exacerbation (succinates strongly irritate the mucosa of the digestive tract);
    gastritis with hypersecretion;
    high blood pressure;
    urolithiasis (YaK stimulates metabolism, which leads to more intensive formation of oxalate stones);
    severe form of gestosis of pregnant women;
    glaucoma.
YaK excites the brain (the drug has an effect opposite to the action of tranquilizers and glycine), so do not take the pill at night.

Side effects

Hypersensitivity reactions, gastralgia, hypersecretion of gastric juice. In people prone to hypertension, the increase in blood pressure is possible due to the systematic use of drugs of the YaK.

Tablets of succinic acid: instructions for use for buyers

In accordance with the instructions for use, succinic acid is taken before meals, previously dissolved in fruit / berry juice or mineral water.
The daily dose for an adult is 0.5-3 tablets. The duration of the course is 4 weeks.
At pregnancy the dose depends on term. At the time of 12-14 weeks pregnant women are prescribed an additive of 0.25 g per day for a ten-day course. In the second trimester the drug should be drunk between 24 and 26 weeks, in the third - about 10-25 days before the birth. During the entire period of pregnancy it is allowed to take no more than 7.5 grams of YaK.
To prevent poisoning products of alcohol breakdown it is recommended to take half an hour to an hour before drinking 0.25 g of YaK. With alcohol withdrawal, the treatment is continued for 4 to 10 days. The daily dose of 0.75-1 g of YaK is divided into 3-4 doses. The supplement can be taken as an independent agent, and in combination with other pharmacological preparations.
To improve appetite, it is shown to take 0.25 g of YaK from 1 to 3 times a day, before meals. If the intake is accompanied by a feeling of heaviness in the epigastric region, the tablets are drunk after eating. The duration of the course is from 3 to 5 days.
As an irritant of the gastric glands before the study of the secretory capacity of the stomach, the YaK is taken on an empty stomach on 1 tablet, first dissolving it in a dessert or a tablespoon of water. The study is carried out at standard time intervals, using conventional methods of analysis.
Oncological patients for prophylactic purposes daily intake of 2-3 tablets 0.1 g are shown. If necessary, the dose is increased to 5-10, and in especially severe cases - up to 20 tablets per day.
During periods of exacerbation of seasonal diseases, YaK for prevention is taken twice a day for 0.5 g of course lasting 2-3 weeks. With influenza and acute respiratory viral infection at the initial stages of the disease, tablets are taken 1 or 2 times a day for 3-4 pills per reception. With hyperthermia, YAK should be drunk in combination with Aspirin.
Application of YAK in cosmetology allows you to slow the aging of the skin, clean it at the cellular level and bleach, remove scars, pimples and swelling, remove the slag and saturate with oxygen.
For the face, neck, décolleté and skin around the eyes are used in serums, masks, lotions, creams, peelings. Cosmetics with the addition of YAK is used in almost all anti-aging programs.
To prepare a cream with YaK it is enough to add a tablet dissolved in a teaspoon of flower water to 20 ml of a suitable type of skin cream. For the tablet to completely dissolve, it is left in the water for several hours.
To make a mask, you just put on the skin crushed powder and mixed with flower water to consistency thick sour cream tablets. After 15-20 minutes, the mixture is washed off and applied to the skin with a cream. Women with dry skin can repeat the procedure no more than once a week, with oily skin a mask is allowed to do three times a week.
To prepare the tonic, the following ingredients should be mixed: scented water (50 ml), 10 drops of ylang ylang and rosemary oil, 2 powdered tablets of YaK, benzyl alcohol (0.5 ml). Alcohol acts as a preservative. If the tonic is stored for a short time (not more than 7 days) and in the refrigerator, it can not be added.
To make less visible scars and stretch marks, you should prepare a thick mixture of flower water and YaK, apply it to the problem area and massage for 1-2 minutes. After 15 minutes, you can wash off the leftovers for peeling and apply cream or milk on the skin.
No less useful for stretch marks and mask with mummies. For its preparation, several tablets of mummy and several tablets of YaK are dissolved in a small amount of olive or almond oil. When the mass becomes uniform, it is applied to problem areas and the skin is massaged properly. After an hour, the mask is rinsed off with cool water.
The result is noticeable with systematic application. It is optimal to do the procedures every day for 3 weeks, then maintain the break and, if necessary, repeat the course.
The use of YaK for hair helps to increase the flow of blood to the scalp, strengthens the hair, makes it more hydrated, shiny and obedient.
The product can be added to ordinary shampoos and masks, and can be rubbed into the scalp, previously soaking in a small amount of water / hydrolyte. After applying the paste to the hair, the head is wrapped with a towel for 2 hours (you can leave the mask and longer). The procedures are repeated daily for a month.

Overdose

Overdosage of succinic acid is impossible.

Interaction

Succinic acid is compatible with most pharmacological agents. The exception is anxiolytics and barbiturates (succinates reduce their effectiveness).
Can be used as an adjuvant in the complex therapy of infectious diseases to reduce the toxic effects of other drugs, including antibiotics, anthelmintic, anti-tuberculosis and anti-inflammatory drugs.

Terms of sale

The product is sold without a prescription.

Storage conditions

Store the drug in a place inaccessible to children, protected from moisture at a temperature of up to 25 ° C.

Shelf life

After you buy sucinic acid, tablets are suitable for use within 4 years after the release date.

special instructions for buy succinic acid

What is succinic acid and why do succinates need the body?
Amber or butanedioic acid is a dibasic carboxylic acid, which has the appearance of colorless crystals and is readily soluble in alcohol and water.
In small quantities, this organic compound is found in some vegetables and fruits, but the main source for medicine, food and chemical industry is natural amber.
The chemical formula of the substance is HOOC-CH2-CH2-COOH.
According to Wikipedia, succinate participates in tissue respiration of oxygen-breathing organisms.

The use and harm of succinic acid

The most valuable properties of YaK are its ability to facilitate the adaptation of the organism to stressful situations and protect it from various kinds of toxic poisoning.
This makes it possible to effectively use the supplement as an adjunct to the main therapy with a fairly wide range of diseases.
Nevertheless, with uncontrolled use of YaK can harm the body. The agent has a number of contraindications and is not intended for systematic daily administration. As a rule, the additive is drunk no more than 4 weeks.

Application of succinic acid in plant growing

For plants, succinic acid is an anti-stress and growth stimulant.
The use of succinic acid for plants is possible in several ways. For seedlings, spraying of all parts of the plant (roots, leaves, stems) is shown, as well as soaking the roots before planting for 0.5-4 hours (after soaking the roots are dried for half an hour and then planted in the soil).
Seeds of plants before planting are recommended to soak in a solution of succinic acid for 24 hours, after that the planting material is allowed to dry out a little and planted in the prepared soil.
For flowers, the solution is a means of intensive therapy: it is planted with plant roots and sprayed aboveground parts of the plant.
In case of problems with the turgor, the tops for flowers (and, in particular, for orchids) use a solution of succinic acid with glucose, nicotinic acid and vitamin B1 (1 tablet of each component per 1 liter of water).
To prepare a solution for watering, 1-2 tablets (sometimes 4) are poured with a liter of hot water, and then cooled. For indoor plants, treatment with such a "medicine" should be conducted no more than once a month.

Succinic acid and alcohol

Accepted alcohol in the liver very quickly turns into acetaldehyde. The use of succinic acid accelerates the decomposition of acetaldehyde into less harmful substances for the body, accelerates detoxification and improves overall health.
You can take the additive:
    before drinking;
    with hangover syndrome;
    for the treatment of alcohol withdrawal.
As part of complex therapy, it is possible to use alcoholism. Course use within a few months is allowed only on the prescription of the doctor and only after the patient has undergone a comprehensive examination.

The use of succinic acid in a hangover

Many toxicologists tend to consider succinic acid as the No. 1 remedy for a hangover. Influencing the cycle of tricarboxylic acids, which is the key link in the energy metabolism, succinate stimulates it in accordance with the principle of mobile equilibrium and promotes the removal of under-oxidized metabolic products.
If drinking alcohol was accompanied by a plentiful snack, it is recommended to supplement the use of YaK with enema.
To remove hangover syndrome, it is recommended to take one tablet of 0.1 g every 50 minutes. The maximum daily dose is 6 tablets. Higher doses can trigger heartburn.
To prevent a hangover about an hour before the planned feast should take 2 supplement tablets. The action develops in half an hour and lasts from 2 to 3 hours.

Succinic acid for weight loss

The positive effect of using succinic acid for weight loss is due primarily to the ability of the substance to purify the body of accumulated toxins, to activate the function of the digestive system and to remove excess water from the body.
Analyzing reviews of nutritionists about the effectiveness of the drug, we can conclude that for weight loss it should be used only as an additional stimulant of metabolic processes. Without adjusting the diet and exercise, you will not be able to get rid of the stores of subcutaneous fat.
Losing weight is recommended to take a three-day course of 3-4 tablets a day. The fourth day is made unloading: the tablets are not drunk, and they also restrict eating and exercise.
The second option involves a daily intake of 30 grams of 1 gram of succinic acid. The whole dose is taken at one time before breakfast.

Application in pregnancy

The use of succinates during pregnancy makes it possible to facilitate the hormonal restructuring of the female body, helps to strengthen the immune system, and also reduces the frequency and severity of toxicoses, prevents the decline of strength and complications of pregnancy, helps to compensate for increased energy expenditure, ensures the creation of the optimal environment for fetal development in which the latter is adequately provided with nutrients and oxygen.
YAC acid helps to strengthen the histohematological barrier between the blood and the fetus, which in turn helps protect the fetus from the effects of pathogens and toxins.
Thus, the risk of a child with congenital diseases or malformations is significantly reduced.
It is important to remember that during the entire pregnancy period it is contraindicated to take more than 7.5 g of YaK.

Reviews about Succinic Acid

The doctors' comments on amber acid are positive. From a medical point of view, succinate is not considered a medicine, but a biotic. That is, a substance that takes part in physiological processes, regulating and normalizing them, as well as increases the body's resistance to external agents.
If we are talking about diabetes, atherosclerosis, infertility, thyroid dysfunction, succinic acid can be a good addition to the basic therapy.
A positive effect on the body is due to the ability of succinic acid to lower cholesterol, stimulate energy production in cells and improve tissue respiration, stimulate insulin levels, improve blood flow.
As for the reception of succinic acid for weight loss, the opinions of specialists are unambiguous, - to lose those extra pounds this supplement will not help. The only effect you can count on is the placebo effect.
However, after the course of application of the drug from the body, at least, the excess fluid (and, consequently, the swelling) will go away, the health will improve, the working capacity will increase and the skin will tighten.
The ability of succinic acid to rejuvenate and restore the skin allows you to actively use this supplement in cosmetology. In addition to home-made creams and tonics, there are special agents on the market in which the effect of the main component on the pathogenetic processes of skin aging is enhanced by the use of other organic compounds in combination with it.
Thus, for example, in the Hyaloal injection, which is aimed at improving the color, texture and texture of the skin, as well as reducing the depth and depth of wrinkles, a complex anti-aging effect is achieved through a combination of succinic and hyaluronic acids.
Despite all the benefits of succinic acid, it must be remembered that this drug is intended for use in short courses, and for a number of diseases it is strictly forbidden to use it.