Diacarb tabs 250mg #30

Instruction for Diacarb tablets

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Composition

The drug contains acetazolamide as an active ingredient.
Additional components: potato starch, sodium starch glycolate, talc.

Form of issue

Produced in the form of round flat tablets of white color.

pharmachologic effect

Diuretic and decongestant.

Pharmacodynamics and pharmacokinetics

Diacarb tablets are diuretic. Their diuretic effect is associated with the inhibition of carbonic anhydrase, which takes part in the exchange of carbonic acid. The inhibition of the action of this enzyme occurs in the tissue of the kidneys. As a result, the degree of reabsorption into the blood from the urine of sodium ions and bicarbonate is reduced.
This drug also helps with pulmonary heart disease, which can occur with certain lung diseases, for example, with emphysema. In addition, it can be used with excessive intracranial pressure. It inhibits the carboanhydrase of the brain, which leads to a decrease in the formation of cerebrospinal fluid and intracranial pressure. Accordingly, the associated symptoms are removed, for example, a headache.
Once in the body, the drug also inhibits carbonic anhydrase ciliary body that causes its application for acute attacks of glaucoma. Its action causes a decrease in the secretion of aqueous humor and normalizes its outflow.
In general, tablets are widely used in the retention of water and sodium in the body, as well as in preventing edema of various origins. Thus, they can be used in the therapy of many diseases. Helping in the normalization of water-salt metabolism, they do not violate the acid-base balance. Duration up to 12 hours.
After oral administration in a dosage of 500 mg, the maximum concentration of the drug in the blood plasma is reached after 2 hours. Its action is characterized by a high degree of connection with plasma proteins. The active substance penetrates the placental barrier.
The medicine is excreted through the kidneys in an unchanged form, mainly during the day.

Indications for use of Diacarb

Only as a diuretic drug Diacarb is rarely used, because there are more effective drugs of this series. But it is often used in diseases not related to the genitourinary system, if there are appropriate indications for the use of Diacarb.
It is not recommended to take these pills alone, without consulting a doctor, from which they will help and how will act, only the specialist knows.
Indications for use of Diacarb are as follows:
    Edema syndrome (moderate or mild degree of severity);
    Epilepsy (as one of the means of combined treatment);
    Glaucoma;
    Mountain sickness;
    Some pulmonary diseases, when a lot of carbon dioxide and bicarbonates accumulate in the blood.

Contraindications

You can not use the tool in case of hypersensitivity to its components, liver failure, acidosis, Addison's disease, diabetes, breastfeeding, pregnancy, acute renal failure, hypokalemia, gipokortitsizm, uremia.
With caution, it is prescribed for edemas of hepatic and renal origin, as well as when using high doses of acetylsalicylic acid.

Side effects

Side effects while taking the drug may be as follows: hypokalemia, convulsions, paresthesia, anorexia, pruritus, rash, muscle weakness, skin flushing, feeling of noise in the ears, metabolic acidosis, myopia.
When long-term therapy may appear nephrolithiasis, glycosuria, leukopenia, disorientation, drowsiness, vomiting, allergic, hematuria, hemolytic anemia, agranulocytosis, impaired touch, nausea, and diarrhea.
If side effects have occurred while taking this medication, the doctor should be consulted immediately.

Instructions for use Diacarb (Method and dosage)

Those who are prescribed Diacarb tablets, the instruction for use informs that the regimen may be different depending on the disease, the characteristics of the organism and the age of the patient.
In the case of edematous syndrome, the initial daily dosage is 250-375 mg. You need to take the medication once a day. The maximum diuretic effect is manifested after 1-2 days of admission. Then it is advisable to take a break for 24 hours. When receiving the medication instruction on the Diamox recommends passing the therapy of circulatory insufficiency, potassium fill level and to comply limited to salt intake diet.
With open-angle glaucoma, the medication is taken several times a day. The dose is 250 mg. In the case of secondary glaucoma, 250 mg administration is given every 4 hours. Children are prescribed 10-15 mg per 1 kg of body weight per day. The daily dosage should be divided into several doses.
Tablets in a dosage of 500-1000 mg / day are recommended to take before climbing the mountain for 1-2 days. If the symptoms of mountain sickness are still manifest, it is necessary to continue therapy for two days.
In epilepsy, adult patients are given 250-500 mg of medication per day. The course is designed for 3 days. Then you need to take a break. In turn, the instruction for the use of Diacarb for children provides the following daily dosages depending on age:
    4-12 months - 50 mg;
    2-3 years - 50-125 mg;
    4-18 years - 125-500 mg.
When combined with anticonvulsants, the initial daily dosage is 250 mg. If required, it can be increased. But children can not take a daily dose of more than 750 mg.
For any indication, if reception was missed, the next dose should not be increased.

Overdose

In the case of using the drug in elevated doses, it is likely that side effects will increase. Treatment is symptomatic.

Interaction

With the combination of Diacarb with antiepileptic drugs, it is possible to increase osteomalacia. And the interaction with diuretics and Theophyllin leads to a significant increase in diuretic action. But this does not apply to acid-forming diuretics. In this case, the diuretic effect, on the contrary, decreases.
In addition, the drug increases the likelihood of the toxic effect of salicylates, carbamazepine, nondepolarizing muscle relaxants, drugs with digitalis, Ephedrine.

Terms of sale

To buy Diacarb you don't need a prescription.

Storage conditions

Keep the medicine in a dry place inaccessible to children at a temperature of up to 25 ° C. Tablets should be protected from exposure to sunlight.
Shelf life - five years.

Diacarb for children

In the case of hydrocephalus or hypertensive-hydrocephalic syndrome, Diacarb is often prescribed for children. It regulates the amount of cerebrospinal fluid. In addition, Diacarb for children may be prescribed for glaucoma or epilepsy.
It is prescribed by prescription, since the use of this medicine requires control by a specialist. It is best to use it in a hospital environment, when monitoring the child's condition can be carried out at the proper quality level.
However, to date, it is not uncommon for a neurologist to prescribe a drug at home if the condition is mild.
Parents should be aware that this remedy can provoke serious adverse reactions. It is necessary to observe the state of the child, as cramps, nausea, muscle weakness, hypokalemia, vomiting, allergic reactions may appear. And with prolonged admission in children, there is sometimes a decrease in the number of leukocytes and hemolytic anemia. Often, if a long course is needed, Asparkam can also be prescribed to reduce the withdrawal of potassium from the body.
Usually, the doctor selects the dosage himself after examining the child and obtaining the results of the tests. According to the instructions, the minimum dosage is 50 mg per day. The daily dose is given to a child in 1-2 hours.

Diacarb for newborns

Children up to one year can be prescribed this drug for epilepsy. In addition, Diacarb for newborns is used when excessive increase or divergence of the seams of the skull. It helps to reduce the amount of cerebrospinal fluid.
Newborn this medication is prescribed by a doctor. Admission Diacarb requires careful monitoring of a specialist.
The best option is to monitor the baby in a hospital throughout the course. Nevertheless, often this drug is given at home. In this case, the specialist is obliged to warn parents of possible side reactions and to specify exact terms of admission (no more than 5 days). Upon completion of the course, you must again pass the appropriate tests.

During pregnancy (and lactation)

This drug should not be taken during pregnancy. If you need to take the drug during lactation, breastfeeding should be discontinued.

Reviews about Diacarb

Opinions about the drug can be found very different. Some reviews of Diacarb report that the medicine has helped, and in others - people complain of side effects. In the latter case, it is especially often told about the appearance of convulsions and muscle weakness. But in general, positive reviews of Diacarb still occur more often.
Some forums are also interested in whether this drug can be used during pregnancy. Experts give a unambiguously negative answer to this question. Pregnant women are not prescribed a drug.