Driptane tabs 5mg #30

Driptane instruction for use

You can buy Driptane here

Composition

In the composition of one tablet:
    oxybutynin hydrochloride - 5 mg;
    anhydrous lactose;
    ICC;
    calcium stearate.

Form of issue

The drug is released in the form of round tablets. White color. Tablets have a biconvex shape and risk on the one hand. The medicine is packed in blisters, in cardboard packages of 30 or 60 tablets.

pharmachologic effect

Spasmolytic.

Pharmacodynamics and pharmacokinetics

Oxibutin has a direct spasmolytic effect on the detrusor smooth muscle fibers. The substance blocks the effect of acetylcholine on m-holinoblokatory of the bladder. Then the detrusor relaxes, its volume, on the contrary, increases, the frequency of spontaneous urge to urinate decreases.
After a quick and almost complete absorption in the digestive tract, the active substance enters the systemic circulation. After one hour, its concentration is maximal. The concentration reduction curve is an exponential, the half-life is approximately 3-4 hours.
Within 8 days of systematic reception of the drug, its equilibrium concentration in the blood plasma is reached. If patients of advanced age lead an active lifestyle, the drug does not accumulate in organs and tissues. However, in weakened patients, there is an increase in pharmacokinetic parameters. The active ingredient tends to be metabolized in the liver, and its metabolites also have a blocking effect on m-cholinergic receptors. The drug is excreted through the kidneys in the form of metabolites.

Indications for use

The drug is prescribed:
    for the treatment of urinary incontinence, with various neurogenic disorders;
    with idiopathic disorders of detrusor function.
Also indication for the use of the drug is incontinence (nocturnal enuresis) in children over 5 years old.

Contraindications

The medicine is contraindicated:
    at a closed angle glaucoma;
    when allergic to its components;
    atony of the intestine;
    with ulcerative colitis;
    obstructive uropathy;
    lactating women;
    children under 5 years;
    with obstruction of the gastrointestinal tract;
    with the expansion of the colon;
    with myasthenia gravis;
    with a tendency to bleeding or if they are present.

Side effects

The most common side effects are:
    diarrhea, nausea, pain and discomfort in the abdominal area, constipation;
    mydriasis, problems with accommodation;
    cardiac arrhythmia, decreased libido in men, impotence;
    allergies, headaches, insomnia, dizziness, weakness, increased intraocular pressure.

Instructions for use Driptane (method and dosage)

Orally. The tablet can be divided or crumbled.
Driptane, instruction for adults
The recommended daily dosage is 10-15 mg, divided into 2-3 doses. The maximum daily dosage (20 mg) can be prescribed only after consultation with the doctor and with the normal tolerability of adverse reactions.
For the elderly, a dose adjustment is necessary. As a rule, appoint 2.5 mg, 2 times a day. The maximum daily dosage is 10 mg.
For children from five years, usually prescribed 5 mg per day, divided into 2 doses. Dosage can be increased to 5 mg 3 times a day after consultation with a specialist. For the treatment of nocturnal enuresis, the last tablet should be taken directly before bedtime.

Overdose

Symptoms of overdose are: overexcitation of the nervous system, hot flashes, lowering blood pressure, paralysis, coma, respiratory failure, dizziness.
Treatment: gastric lavage, symptomatic therapy, artificial ventilation, use of neostigmine, diazepam or propranolol. If urinary retention occurs, the bladder can be catheterized.

Interaction

The action of the drug may weaken other m-cholinomimetics.

Terms of sale

To buy Driptane the prescription is not required.

Storage conditions

Do not allow children to fall into the hands. Store in a cool place in the original packaging.
Shelf life - 3 years.

special instructions

Special care should be taken when treating children with oxybutynin from 5 years due to an increased likelihood of adverse reactions, especially the side of the nervous system.
With caution appoint elderly patients with autonomic neuropathy, diseases of the digestive tract, kidney or liver, porphyria.
It is not recommended to prescribe the drug to pregnant women.
It is necessary to refrain from driving a car or other mechanisms that require a high concentration of attention, while taking the medicine.

Reviews about Driptane

Feedback on the forums are different. Some drugs help, urge to urinate, especially at night, becomes less. However, many complain about the occurrence of allergies, headaches and other side effects. In their opinion, the medicine is not effective enough.
Reviews about Driptane for children are ambiguous. Doctors often prescribe Driptane for enuresis and bedwetting in children. But due to the fact that side effects in children are more often and more pronounced, parents stop giving the drug to their children. Many believe that the drug is not suitable for children, replace it with analogs.