Furamag caps 50mg #30

Furamag user manual

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Composition

Potassium furazidin and excipients: magnesium hydroxycarbonate, potassium carbonate.

Form release

Capsules of 25 mg and 50 mg.

Pharmacological action

Antimicrobial.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Often the question is-is it an antibiotic or not? Furamag is an antimicrobial drug of nitrofurans group having a wide spectrum of action. Thinking that Furamag an antibiotic, many refuse its reception (especially in children). This is totally unjustified.
First of all, nitrofurans does not inhibit the immune system, but activate it, because in therapeutic doses stimulate leukopoiesis and increase the ability of leukocytes to phagocytize (capture) microorganisms.
Secondly, resistance to Furamag very slowly. It acts on gram-positive and gram-negative microbes resistant to antibiotics. With respect to E. coli, Proteus morganii, Proteus mirabilis and Staphylococcus spp. Furamag is more active than other nitrofurans. There is a high activity (compared to other antimicrobials) to Enterococcus faecalis and Staphylococcus spp. Third, in contrast to antibiotics, Furamag almost does not suppress beneficial microflora of the intestine.
The mechanism of action of the drug is in violation of cellular respiration and biosynthesis of nucleic acids of microorganisms, suppression of Krebs cycle. There is a destruction of the shell of microorganisms. Under the action of Furamag during the destruction of the microorganisms produces less toxins and the therapeutic effect is achieved faster.

Pharmacokinetics

Absorption of the drug occurs in the small intestine, and from the proximal part more than from the distal. Eating contributes to a more active absorption.
When taking 50 mg maximum concentration in blood after 3 hours (lasts 6 hours), the urine appears after 2-4 h concentration in the urine higher than in the blood. The drug is slightly biotransformed and the daily dose is excreted by the kidneys for 24 hours.

Indications for use

Infections caused by sensitive microorganisms:
urogenital infections (pyelonephritis, cystitis, urethritis);
infected burns;
skin and soft tissue infections;
prostatitis;
gynecological infections.
Prophylactically appointed urological manipulation (cystoscopy, catheterization) and operations, as well as to prevent recurrence of urinary tract infections.

Contraindications

intolerance of nitrofuran group preparations;
polyneuropathy;
pregnancy;
lactation;
renal failure;
porphyria;
age up to 3 years (encapsulated form of the drug).

Side effect

Furamag is slightly toxic, so very rarely observed adverse reactions: headache, drowsiness, peripheral neuropathy, nausea, flatulence, vomiting and allergic reactions (itching, skin rash, urticaria). Side reactions should inform the doctor.

Pills Furamag, usage instructions (Method and dosage)

To reduce the risk of side effects development pills Furamag (capsule) taken orally after meals with plenty of liquid.
Adults-50-100 mg 3 times a day.
Children from 1 year to 10 years — 5 mg per kg of body weight, dividing the dose into 3 doses. Body weight over 30 kg — 50 mg 3 times.
Treatment is prescribed for 7-10 days.
At urological manipulations for the purpose of prevention appoint once before procedure to adults and children, respectively 50 mg and 25 mg.
In children under 6 years of age, the use of the drug in capsules is accompanied by a risk of aspiration, so the capsule is opened, and its contents are given to the child in the appropriate dose.
To the question — what pills (capsules) Furamag — can answer: first of all, the drug is indicated for diseases of urinary system. Given the pharmacokinetics (excretion of kidneys in almost unchanged form) and a wide range of actions, the drug Furamag with cystitis is a drug of choice. Furamag with cystitis is prescribed because it has an advantage over Furadonin and Furagin in view of lower toxicity, less frequent side effects, better tolerance, higher concentration in the urine and the long-term effects of the drug. Capsules dissolve in the intestine, which means that there is a much lower risk of gastrointestinal disorders. Furamag in combination with magnesium hydroxide when administered is better absorbed than furadonin, which allows to achieve high concentrations in urine, using the drug at a lower dose. It was revealed that pathogens of urinary tract infections in 83-89% are sensitive to this drug, which is much higher than the sensitivity to Ciprofloxacin, nalidixic acid and Amoxicillin.
Instructions for use should be strictly observed: if you missed the reception of the next dose, the next dose should be taken at the right time, without taking a double dose.

Overdose

In case of overdose there are neurotoxic symptoms: ataxia, neuritis, tremor. For prevention of these phenomena requires the use of b vitamins.

Interaction

It should not be used concurrently with sulfonamides, Ristomycin and chloramphenicol in mind the risk of oppression of hematopoiesis, as well as drugs, "acidifying" the urine.

Terms of sale

To buy Furamag you don't need a prescription.

Storage conditions

Save in a dry place, protecting from sunlight. Storage temperature is not higher than 25°C.
Shelf life - 3 years.

Special instruction

Furamag during pregnancy

There are no reliable clinical studies on the use of furazidin in pregnancy. Therefore, pregnancy is a contraindication to the appointment of this drug.

Work with alcohol

Applying furamag tablets, you can not drink alcohol, because there may appear or increase side effects. Taking into account the fact that the half-life of the drug from the body for about 10 hours, you need to refrain from taking alcohol during the day after the end of treatment.

Reviews of Furamag

Reviews about Furamag mostly positive. Fast and effective — vanish pain and dysuric disorders in the first days of admission, normal color of urine and reduced temperature. There are good results even in the treatment of chronic cystitis.
Certain difficulties arise in the treatment of young children. The capsule has to open and dissolve the contents — the drug is bitter, and the granules dissolve not to the end, which causes a gag reflex. Many note the emergence of adverse reactions: headache, nausea, drowsiness and muscle pain.tients).