Nasobec spray 50mcg/dose 200doses

Nasobec user manual

You can buy Nasobec here

Composition

In one dose of the spray there is an active substance (beclomethasone dipropionate) 50 μg + auxiliary substances (phenylethanol, dextrose anhydride, sodium carboxymethyl cellulose, water, benzalkonium chloride, polysorbate, microcellulose, hydrochloric acid).

Form of issue

The spray is a suspension, white, opaque, without inclusions. In bottles of 100, 180 and 200 doses.

pharmachologic effect of Nasobec

Anti-inflammatory, antiallergic. Removes puffiness.

Pharmacodynamics and pharmacokinetics

The active substance of the drug is a synthetic glucocorticosteroid. It stimulates the reproduction of lipomodulin, which is an inhibitor of the enzyme phospholipase A and delays the synthesis of arachidonic acid. Thus, there is a decrease in inflammatory exudation and synthesis of lymphokines, a slowing down of the process of marginal accumulation of neutrophil cells.
The processes of infiltration and granulation are oppressed due to the ability of beclomethasone to inhibit the migration of macrophages. The edema subsides, the mucus is less produced, the mucociliary transport improves.
The drug is well tolerated, even with very long-term use. Relief of symptoms comes in a couple of days, after the beginning of admission.
When administered as inhalation, does not have a high absorption capacity. An insignificant amount of substance penetrating the digestive tract is destroyed in the liver. Half of the substance is removed from the body after 15 hours, up to 90% of the active substance binds to plasma proteins. The drug with feces is excreted and, slightly, through the kidneys.

Indications for use

The medicine is prescribed for the treatment of rhinitis, including vasomotor and allergy.

Contraindications of Nasobec

    allergy, to any of the components of the medicine;
    hemorrhagic diathesis;
    the first trimester of pregnancy;
    tendency to bleeding from the nose;
    fungal or viral infection;
    tuberculosis of the respiratory tract or organs.
The drug is contraindicated for children under 6 years.

Be careful when:

    glaucoma;
    hypothyroidism;
    ulcers and cuts on the nasal septum;
    in the second and third trimester of pregnancy;
    during lactation;
    with amebiasis;
    with liver diseases;
    recently occurred myocardial infarction;
    After operations or with injuries of the nose.

Side effects

Rarely can arise:

    urticaria, skin rashes, angioedema;
    candidiasis;
    headache, weakness and drowsiness, distortion of taste and smell;
    dryness of the mucous membranes of the mouth and nose, bleeding, coughing, burning and itching in the nose, rhinorrhea.

Cases of occurrence are known:

    ulcers on the nasal mucosa and perforation of the septum;
    decrease in growth rate and thinning of bones in patients of childhood;
    conjunctivitis, glaucoma, impaired vision.

Instructions for Nasobec (Method and Dosage)

The spray is used intranasally.
At the age of more than 12 years, appoint 1-2 doses in each nostril 2 times a day.
For children from 6 to 12 years, the daily dose is up to 400 mg. As a rule, take 1 dose in each pass 2 times a day.
Treatment means continue until there is an improvement in health.
According to the instructions for use of Nasobec, before the first use (or after a long break), the vial should be shaken.
Release a few doses into the air until a white cloud appears.
Then, placing the nozzle of the nebulizer between the middle and index fingers, exhale.
Clamp one finger with a free nasal passage, and spray the drug into another. Spraying is done by inhaling, exhaling through the mouth.
Repeat the above steps for the other nostril.
At the end of the procedure, clean the nozzle of the spray gun with a damp cloth or a clean handkerchief.
It is also recommended to clean the applicator, at least once a week. Spout should be removed, rinsed with warm running water, dried and put on the bottle again.

Overdose

With prolonged use of large doses, hypercorticism may occur. It should, gradually reducing the dose, stop taking the remedy.

Interaction

When combined with phenobarbital, phenytoin, rifampicin, glutetimide and ephedrine, beclomethasone reduces its therapeutic properties.
Simultaneous reception with adrenomimetics, antithrombotic agents, digitalis preparations, oral hypoglycemic drugs and Indapamide, leads to an increased risk of side effects, both on one side and on the other.
The drug reduces the effectiveness of isoniazid.
The drug enhances the effect of antiasthmatics and systemic SCS.

Storage conditions

Keep out of the reach of small children. Temperature regime from 10 to 25 degrees.

Shelf life

4 years. If the vial has been opened, then it should be used no more than for 3 months.

special instructions

Avoid contact with eyes.
The effect of taking the medication does not appear immediately, sometimes it can take up to 7 days to reach it. During this time, you should not try to reduce the dosage or stop taking the medication.
Use the medicine on the damaged mucous membrane until the wound and ulcers are completely healed.
Pay special attention to people with an increased risk of developing adrenocortical insufficiency and small children.
Be careful when driving and handling vehicles during taking the drug.

Reviews about Nasobec

Reviews about Nasobec are mostly positive. Many are struggling with this tool not only with allergies, but also with symptoms of sinusitis, when vasoconstrictive drugs no longer help. In combination with antibiotics, the drug copes with sinusitis.
Some patients who have acquired dependence on vasoconstrictors fight it with the help of Nasobec. Side effects are rare, many like the floral scent of the drug and a convenient form of release. Also attracts a relatively low cost of the drug.