Orgametril tabs 5mg #30

Orgametril instruction

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Composition

The tablets include an active ingredient of linestrenol.
Additional ingredients: potato starch, glycerol, α-tocopherol, talc, magnesium stearate and lactose monohydrate.

Form of issue

It is produced in the form of tablets 30 tablets in a blister, one blister in a pack.

pharmachologic effect

The drug has progestagenic effect.

Pharmacodynamics and pharmacokinetics

Orgametril is a synthetic progestogen, intended for internal reception. Its active component is characterized by pharmacological properties similar to natural Progesterone. When treating this drug shows a pronounced progestogenous effect on the endometrium. Continuous use helps suppress ovulation and menstruation. Therefore, the drug is prescribed when it is necessary to display its pronounced progestogen effect.
Inside the body, linestrenol undergoes rapid absorption and is converted to active norethisterone. Metabolism occurs in the liver. The maximum concentration of norethisterone in the blood plasma is found after 2-4 hours from the time of taking the drug. Removal of the substance occurs with the help of the kidneys and intestines.

Indications for use

The drug is recommended for use when:
    dysfunctional uterine bleeding;
    amenorrhea;
    oligomenorrhea;
    dysmenorrhea;
    premenstrual syndrome;
    endometriosis;
    endometrial carcinoma;
    a benign breast tumor;
    postponement of normal menstruation;
    hormone replacement therapy with estrogen - in complex treatment.

Contraindications for use

Organometril is not assigned to patients with:
    severe diseases and violations of the liver;
    vaginal bleeding of unknown origin;
    severe itching or herpes caused by treatment with steroid drugs;
    pregnancy.

Side effects

In the treatment of organometriol, various undesirable effects may develop, for example: nausea, weight gain, development of heavy bleeding and spotting discharge.
In rare cases, there is: headache, nervousness, dizziness, migraine, depression, jaundice, chest pain, changes in liver function. There was also a decrease in glucose tolerance, acne, chloasma, rashes and skin itching, hirsutism. After discontinuation of treatment, the development of swelling and amenorrhea is possible.

Instructions for use Orgametril (Method and dosage)

This drug is intended for ingestion by washing with liquid. If you miss a regular tablet, you must take it immediately, except for a delay in taking more than 24 hours.
It should be noted that the first day of the cycle is the onset of menstrual bleeding.
In the case of polymorphic administration, a daily dosage of 5 mg or one tablet is prescribed, which must be taken 14-25 days during the menstrual cycle.
Treatment of menorrhagia and metrorrhagia requires taking two tablets a day for 10 days. As a rule, after a few days the bleeding stops. Therapeutic course is recommended to repeat and the next three menstrual cycles in dosage for admission on days 14-25. When treatment is ineffective, an additional examination is prescribed and appropriate therapy is selected.
In any case, the drug is prescribed by the attending physician, which determines the dosage and the regimen of therapy. Diagnosis is regularly carried out to confirm the effectiveness of treatment. The use of the drug without the appointment of a specialist is contraindicated.

Overdose

In cases of overdose, nausea and vomiting may occur.
Treatment is carried out depending on the symptomatology.

Interaction

The simultaneous use of Orgametril with Rifamycin, Hydantoin derivatives, barbiturates, carbamazepine and Aminoglutethimide, laxatives and Activated Carbon - significantly reduces its effect. However, he himself is able to increase the therapeutic, pharmacological or toxicological effects of Cyclosporine, Trolandomycin, Theophylline and beta-blockers.
The combination with antibiotics from the macrolide group sometimes leads to the development of toxic liver damage.
It is noted that this drug lowers the properties of Insulin.

special instructions

The use of drugs with a high content of estrogen or progestagen can lead to the development of chloasma. Therefore, women who are predisposed to this need to be careful not to get on the skin of UV rays.
Sex hormones have an effect on specific laboratory parameters. As a result, there may be an increase in the LDL level in the blood or a decrease in the level of HDL. There are some changes in the functioning of the liver, carbohydrate metabolism and blood clotting.
In the course of treatment, regular monitoring of the condition of patients with circulatory disorders is required, since hormonal substances can increase the risk of manifestations of cardiovascular or cerebrovascular disorders.
Also, you should limit the intake of fats and carbohydrates, especially if women have a tendency to increase their body weight.
For patients with diabetes it is necessary to control the glycemic profile in order to timely adjust the dose of insulin.
When there are dysfunctional uterine bleeding in women of reproductive age, the therapy is performed only after treatment and diagnostic curettage of the uterine cavity.
With ineffectiveness of therapy, manifested by relapses of bleeding and hyperplastic processes of the endometrium, urgent clarification of the causes of bleeding is necessary.
A prolonged delay in menstruation during treatment requires a survey to exclude the presence of an ectopic pregnancy.
It is known that lactose is present as an additional substance in the Orgametril. For this reason, the drug is contraindicated for admission to patients with hereditary disorders, for example, intolerance to galactose, lactase deficiency lapp, and glucose-galactose malabsorption.

Storage conditions

Tablets are stored in a dry, dark, cool place, inaccessible to children.
Shelf life - 5 years.

Orgametril and alcohol

While taking this medication, you can consume alcohol, but within reasonable limits.

Reviews about the Orgametril

A variety of drugs designed to treat violations of the reproductive and sexual systems in women, especially actively discussed in the network. At the same time, reviews about the Orgametril in the forums devoted to this problem are in most cases positive.
Treatment with this drug is prescribed for women of different ages, setting a dosage and therapeutic regimen, depending on the type and complexity of the gynecological impairment. Of course, to show its effectiveness, it is necessary to undergo long-term therapy, which lasts for several months. It is also possible to prescribe additional drugs and procedures.
In addition, women say that the drug is not only highly effective, but also does not cause the development of side effects. As is known, some patients are concerned about the problem of excess weight, but if the treatment is chosen correctly, the body weight does not increase.