Groprinosin tabs 500mg #30

User manual for Groprinosin

You can buy Groprinosin online

Composition

The composition of 1 tablet Groprinosin contains:
    inosine pranobex - 500 mg (active substance);
    auxiliary substances: povidone K25, magnesium stearate, potato starch.

Form of issue

Grogrinosin white tablets (sometimes almost white), have oblong form and risk on one side. This drug is produced by 10 tablets in a blister, to the carton can be 2 or 5 blisters.

pharmachologic effect

The drug is used as an immunostimulating and antiviral agent.

Pharmacodynamics and pharmacokinetics

Groprinosin is an immunostimulating drug that also has an antiviral effect. This drug is effective because of the inosine contained in it, and its second component (para-acetamidobenzoic acid salt) is able to increase the level of availability of inosine for lymphocytes. It blocks the multiplication of the virus particles.
Groprinsin can also be prescribed as an additional therapeutic agent in case of Herpes simplex virus infection of the skin and mucous membranes. In this case, faster healing is observed, the severity and duration of the disease decreases with external application of the drug.
Tablets are quickly and more than 90% absorbed, have high bioavailability. After 1 hour, the maximum concentration of the active substance in the plasma is reached, the half-life is about 50 minutes. The drug begins approximately 30 minutes after it is taken and lasts for 6 hours.

Indications for use

Groprinosin should be taken in the following cases:
    when the following infectious diseases occur: influenza, measles, adenovirus and rhinovirus infections, parainfluenza, acute respiratory diseases, bronchitis of viral etiology, parotitis epidemic;
    in diseases caused by the Herpes simplex virus type I or type II (herpes of the skin of the face, lips, hands, mouth mucosa, ophthalmoherpes), the virus Varicella zoster;
    at chronic relapses of occurrence of infections of the genitourinary system and respiratory tract in patients with weakened immunity (chlamydia, etc.).

Contraindications

Groprinosin has the following contraindications:
    hypersensitivity to one of the components of the drug;
    artium;
    urolithiasis disease;
    gout;
    chronic renal failure;
    pregnancy and lactation;
    children under 3 years.
With special care, the drug can be used simultaneously with xanthine oxidase inhibitors, zidovudine, diuretics, as well as with acute liver failure.

Side effects

The use of this drug may cause some side effects:
    fatigue, dizziness, headache, sometimes - insomnia, nervousness, drowsiness;
    rash, itching;
    exacerbation of gout, joint pain;
    nausea, decreased appetite, vomiting, sometimes - constipation, diarrhea;
    allergic reactions;
    polyuria;
    increased levels of urinary acid in urine and blood.

Instructions for use Groprinosin (Method and dosage)

The medicine is taken inside, after eating, it should be taken with a small amount of water 3-4 times a day in an equal amount of time (6-8 hours).
Instructions for adults: 6-8 tablets, eat 3-4 times a day.
Instruction for Groprinosin for children from 3 to 12 years: 3-4 consumptions of 50 mg / kg per day.
In severe infections, you can increase the dose. For adults, the maximum daily dose is 3-4 g in 4-6 receptions, for children - 50 mg / kg per day.
In acute diseases, the course lasts from 5 to 14 days, the course should be continued for another 2-3 days for prevention and after the disappearance of symptoms.
In case of recurrent chronic illnesses, the treatment session can be 5-10 days with possible intervals of 8 days. The total duration of treatment is 30 days, while you can reduce the dose to 500 mg per day.
In the treatment of infections that are caused by the herpes virus, for children and adults, a course lasting 5-10 days is spent until the symptoms disappear. To reduce the possibility of relapse, it is recommended to conduct additional courses of 1 tablet twice a day for 30 days.
Groprinosin 500 children under 3 years is strictly contraindicated. For the elderly, the daily dose is the same as for middle-aged people. When treating Groprinosinom people suffering from renal and hepatic insufficiency, it is necessary to conduct a procedure every 14 days to check the level of entry of uric acid into serum and urine. With a longer treatment with the drug every 4 weeks, it is recommended to monitor the activity of liver enzymes.

Overdose

In studies of cases of overdose was not observed. Overdose can lead to an elevated level of uric acid concentration in the blood serum and urine. In this case, symptomatic therapy and gastric lavage are recommended.

Interaction

Immunostimulating effect of the drug can be reduced with simultaneous use with antidepressants. When combined with zidovudine, it may be necessary to adjust the value of its dose. With increased caution, use Groprinosin simultaneously with xanthine oxidase inhibitors or loop diuretics.

Storage conditions

Tablets are recommended to store at a temperature of not more than 30 ° C in a place inaccessible to children.
Shelf life - 3 years.

Groprinosin and alcohol

The simultaneous use of Groprinosin with alcohol can adversely affect the liver of the patient. If necessary, you should take a break with a medication for at least 2 hours to alleviate the effects on the body.

Reviews of Groprinosin

Among buyers, most of them note that the drug is effective, but many have noticed side effects such as nausea and loss of appetite. It is often possible to meet feedback on how to take children under 3 years, although according to the instructions it is prohibited.
This is a fairly sparing medicine, so when you appoint Groprinosin to children, reviews are mostly positive. With a clear adherence to the prescribed dose of medication for children, the reviews are reduced to the fact that there is a positive effect and there is a minimum of side effects.
Concerning the efficacy of Gropronosin in HPV, the reviews are positive, after the course of taking the drug in many patients, the level of HPV in the smear decreased.