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Amelotex supp 15mg #6

  • $13.99
  • 3 or more $13.78
  • Availability:In Stock

Amelotex suppositories user manualReed more and buy Amelotex suppositories herepharmachologic effectNSAIDs, has anti-inflammatory, antipyretic, analgesic effect. Belongs to the class of oxycams; an enolic acid derivative. The mech..

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Amelotex suppositories user manual

Reed more and buy Amelotex suppositories here

pharmachologic effect

NSAIDs, has anti-inflammatory, antipyretic, analgesic effect. Belongs to the class of oxycams; an enolic acid derivative. The mechanism of action is the inhibition of the synthesis of Pg as a result of the selective suppression of the enzymatic activity of COX2. When administered in high doses, long-term use and individual characteristics of the organism TsOG2, the selectivity decreases. Suppresses the synthesis of Pg in the area of ​​inflammation to a greater extent than in the gastric mucosa or kidneys, which is associated with relatively selective inhibition of COX2. Rarely causes erosive and ulcerative diseases of the gastrointestinal tract.


Rheumatoid arthritis; osteoarthritis; ankylosing spondylitis (ankylosing spondylitis) and other inflammatory and degenerative diseases of the joints, accompanied by pain syndrome. Designed for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.


Hypersensitivity (including to NSAIDs of other groups), a combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance of ASA and drugs of the pyrazolone series; peptic ulcer and 12 duodenal ulcer (in acute phase), severe liver failure, chronic kidney disease in patients not undergoing dialysis (CC less than 30 ml / min), active gastrointestinal bleeding; progressive kidney disease, severe liver failure or active liver disease, condition after coronary artery bypass surgery, confirmed hyperkalemia, inflammatory bowel disease, children (up to 12 years old), pregnancy, lactation period.

special instructions for Amelotex suppositories

In the event of peptic ulcers or gastrointestinal bleeding, the development of side effects from the skin and mucous membranes of Amelotex suppositories should be canceled.
In patients with reduced BCC and reduced glomerular filtration (dehydration, CHF, liver cirrhosis, nephrotic syndrome, clinically significant kidney disease, diuretic intake, dehydration after major surgeries), the appearance of a clinically expressed CRF is possible, which is completely reversible after discontinuation of Amelotex suppositories (in these patients at the beginning of treatment, daily diuresis and renal function should be monitored). With a persistent and significant increase in transaminases and changes in other indicators of liver function, Amelotex suppositories should be canceled and control tests should be conducted.
In patients with an increased risk of side effects, treatment begins with a dose of 7.5 mg. In the terminal stage of chronic kidney disease in patients on dialysis, the dose should not exceed 7.5 mg / day. During the period of treatment, care must be taken when driving and engaging in other potentially hazardous activities that require increased concentration and psychomotor speed (with the appearance of dizziness and drowsiness). To reduce the risk of adverse events from the gastrointestinal tract, use the minimum effective dose of the shortest possible course.

Dosage and administration

Inside, during meals, in a daily dose of 7.5-15 mg. The maximum daily dose is 15 mg, in patients with severe renal insufficiency who are on hemodialysis, 7.5 mg. With a slight or moderate decrease in renal function (CC more than 25 ml / min), as well as liver cirrhosis in a stable clinical state, dose adjustment is not required. The initial dose in patients with an increased risk of side effects is 7.5 mg / day.
Rectal - 15 mg (one candle) 1 time per day.

Side effects of Amelotex suppositories

Frequency: often - more than 1%; infrequently - 0.1-1%; rarely 0.01–0.1%; very rarely - less than 0.01%.
On the part of the digestive system: often - dyspepsia, incl. nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea; infrequently, a transient increase in the activity of liver transaminases, hyperbilirubinemia, belching, esophagitis, gastroduodenal ulcer, gastrointestinal bleeding (including latent), stomatitis; rarely - gastrointestinal perforation, colitis, hepatitis, gastritis.
From the side of blood-forming organs: often - anemia; Infrequently - change in blood formula, incl. leukopenia, thromocytopenia.
On the part of the skin: often - itching, skin rash; infrequently - urticaria; rarely - photosensitization, bullous eruptions, erythema multiforme, incl. Stevens-Johnson syndrome, toxic epidermal necrolysis.
On the part of the respiratory system: rarely - bronchospasm.
The nervous system: often - dizziness, headache; infrequently - vertigo, tinnitus, drowsiness; rarely - confusion, disorientation, emotional lability.
On the part of the cardiovascular system: often - peripheral edema; infrequently - an increase in blood pressure, heartbeat, "tides" of blood to the skin of the face.
From the urinary system: infrequently - hypercreatininemia and / or an increase in the concentration of urea in the blood serum; rarely, acute renal failure; connection with the reception of meloxicam has not been established - interstitial nephritis, albuminuria, hematuria.
From the senses: rarely - conjunctivitis, visual impairment, including blurred visual perception.
Allergic reactions: rarely - angioedema, anaphylactoid / anaphylactic reactions.

Drug interaction

When taken simultaneously with other NSAIDs, the risk of developing ulcerative lesions of the gastrointestinal tract and gastrointestinal bleeding increases; increases the concentration of Li + in plasma with simultaneous use with drugs Li +; reduces the effectiveness of IUD, antihypertensive drugs; indirect anticoagulants, ticlopidine, heparin, thrombolytics increase the risk of bleeding; methotrexate enhances mielodepressive effect; diuretics increase the risk of kidney dysfunction; cyclosporine enhances nephrotoxic effect; Kolestiramin accelerates excretion.
Myelotoxic drugs increase the hematotoxicity of Amelotex suppositories.

Active substance


Terms of sell

You can buy Amelotex suppositories without a prescription.

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