Osteogenon 830mg #40

Instruction for Osteogenon

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Composition

The core of one Osteogenon tablet contains 830 milligrams of the active ossein hydroxyapatite compound, which in turn consists of collagen (216 mg), non-collagen proteins and peptides (75 mg), calcium (178 mg), calcium hydrogenphosphate (hydroxyapatite) (about 444 mg), phosphorus (82 mg), inactive organic fractions (about 95 mg).
Among the auxiliary compounds that make up the preparation can be isolated colloidal silicon dioxide, potato starch, microcrystalline cellulose, as well as magnesium stearate. The composition of the drug coating contains hypromellose, titanium dioxide, as well as yellow iron oxide, talc and macrogol.

Form of issue

Osteogenon is released in the form of tablets, covered with a light yellow shell and having a biconvex oblong form. In one cardboard package, a nominal volume of 800 milligrams contains, as a rule, 4 blisters of 10 tablets.

pharmachologic effect

The drug inhibits bone resorption, stimulates osteogenesis, and also helps in the formation of bone tissue and simultaneously compensates for calcium deficiency in the body.

Pharmacodynamics and pharmacokinetics

Actively acting medicinal compounds contained in Osteogenon act as regulators of phosphorus-calcium metabolism. This drug has found wide application in the treatment and prevention of osteoporosis due to a double effect on the metabolism of bone tissue. On the one hand, the drug stimulates osteoblasts, and on the other hand it has an inhibitory effect on osteoclasts.
Due to the content of calcium in the composition of the preparation in proportion to phosphorus 1: 2, the drug promotes the absorption of calcium from the digestive tract, thereby contributing to the development of parathyroid hormone, which in turn reduces the resorption of bone tissue.
The drug helps slow the release of calcium from hydroxyapatite, which blocks the manifestation of hypercalcemia. In addition, phosphorus, contained in the chemical composition of the drug, is involved in the crystallization of the same hydroxyapatite, which helps slow the excretion of calcium by the kidneys from the body.
Due to the presence of such an organic compound as ossein in the formulation, bone tissue is remodeling. This process inhibits the resorption of tissues and stimulates bone formation. The osteocalcin contained in the drug binds calcium, thereby promoting the accelerated crystallization of bone tissue, and collagen - forms the bone matrix.

Indications for use

The drug is recommended for use if available:
    osteoporosis of any degree of complexity, including those caused by arthritis, hyperthyroidism, kidney and liver diseases, hyperparathyroidism, as well as immobilization, the use of heparin or GCS;
    osteopenia and violations of the balance of calcium and phosphorus in the body, including during pregnancy, as well as during breastfeeding;
    fractures of bones, as well as for their speedy healing.

Contraindications

The main contraindications to the use of the drug are:
    hemodialysis;
    kidney failure;
    hypercalciuria;
    individual intolerance of medicinal compounds included in the preparation;
    age (forbidden to children under the age of 18).

Side effects

Very rarely, the drug can cause an allergic reaction to the constituents of the drug. In addition, with prolonged use, the drug is able to provoke the development of hypercalciuria, as well as hypercalcemia.

Instructions for use Osteogenon (Method and dosage)

In accordance with the instructions for Osteogenon, adults should take the medicine inside 2-4 tablets no more than 2 times a day for osteoporosis and 1-2 tablets per day for all other medical indications. Duration of drug intake is determined in each case by the attending physician on the basis of the patient's condition.

Overdose

No cases of overdose have been reported.

Interaction

The drug may slow the absorption of antibiotics from the tetracycline group of bisphosphonates, as well as drugs containing iron. Therefore, Osteogenon is well taken together with drugs that have in their chemical composition the above biologically active components, adhering to a 4-hour interval between the use of medicines.

Storage conditions

Osteogenon should be stored at a temperature of no higher than 30 ° C in an inaccessible place for children.

Shelf life

Subject to the rules of storage, the drug retains its active medicinal properties for 4 years.

special instructions

People with impaired renal function should avoid using this medication for a long time.
Patients who are predisposed to urolithiasis, it is vitally important to adhere to a special regimen for the intake and dosage of the drug.
Since Osteogenon contains in its chemical composition a trace amount of sodium chloride, the drug is approved for the treatment of patients who suffer from hypertension.
The drug does not affect the ability to drive vehicles.

Children

The drug is not recommended for use in the treatment of children under the age of 18 years.

In pregnancy and lactation

Since the medicinal compounds contained in the formulation do not adversely affect the health and development of the unborn child, pregnant and breast-feeding women can use the drug.

Reviews about Osteogenon

Most of the reviews about Osteogenon in fractures are positive. It can be said that doctors usually prescribe this medicine when bone tissue of different severity is damaged. People taking the drug note that it does not cause side effects and helps in the prevention and treatment of various diseases associated with damage to bone tissue, including in osteoporosis.
The pregnant women, as well as the nursing mothers who have experienced calcium deficiency in the body, respond well to the drug. The doctors' comments about Osteogenon can be called more than "cool". Many doctors are really skeptical about this drug and its ability to influence the regeneration of bone tissues, and therefore they express quite contradictory opinions that differ from the assurances of the drug manufacturers.
However, the number of doctors prescribing Osteogenon as a stimulant for the mineralization of bone tissue is also great, especially since the effectiveness of the drug in each specific case may differ. Therefore, when there are doubts about the strength of the medicinal effect of the drug, it is advisable to study the state of bone tissue using X-rays, as well as urine and blood tests for calcium content in biological fluids.