Tavegil tabs 1mg #20
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Tavegil tabs instuction for useYou can buy Tavegil hereClinical and pharmacological groupThe blocker of histamine H1 receptors. Anti-allergic drugForm of release, composition and packagingTablets are white or almost white, round, ..
Tavegil tabs instuction for use
You can buy Tavegil here
Clinical and pharmacological group
The blocker of histamine H1 receptors. Anti-allergic drug
Form of release, composition and packaging
Tablets are white or almost white, round, flat, with bevelled edge, with a risk and engraving "FROM" on one side.
Clemastine hydrofumarate 1.34 mg,
which corresponds to the content of clemastine 1 mg
Excipients: lactose monohydrate - 107.66 mg, corn starch - 10.8 mg, talc - 5 mg, povidone - 4 mg, magnesium stearate - 1.2 mg.
10 pieces. - blisters (1, 2, 3, 6) - packs of cardboard.
The histamine H1 receptor blocker, ethanolamine derivative. Has a strong antihistamine and antipruritic effect with a rapid onset
of action and duration of up to 12 hours, prevents the development of
vasodilation and contraction of smooth muscles, induced by histamine.
Possessing an antiallergic effect, reduces the permeability of blood vessels, capillaries, inhibits exudation and formation of edema, reduces itching, exerts an m-cholinoblock effect.
After ingestion, clemustine is almost completely absorbed from the digestive tract. Cmax in blood plasma is achieved in 2-4 h.
The binding of clemastine to plasma proteins is 95%. Is allocated with breast milk in a small amount.
Metabolism and excretion
Excretion from the plasma has a two-phase character, corresponding to T1 / 2 is 3.6 ± 0.9 h and 37 ± 16 h. Clemastin undergoes significant metabolism in the liver. Metabolites in the main (45-65%) are excreted in the urine; The unchanged active substance is found in urine only in trace amounts.
- Pollinosis (hay fever, including allergic rhinoconjunctivitis);
Hives of different origin;
- itching, itching dermatoses;
- acute and chronic eczema, contact dermatitis;
- drug allergy;
- Insect bites.
- diseases of the lower parts of the respiratory tract (including bronchial asthma);
- simultaneous use of MAO inhibitors;
- children's age till 6 years;
- lactation (breastfeeding);
- Hypersensitivity to the components of the drug.
With caution should be used Tavegil in patients with stenosing ulcers of the stomach, with pyloroduodenal obstruction, with obstruction of the neck of the bladder, as well as hypertrophy of the prostate accompanied by a delay in urine, with increased intraocular pressure, hyperthyroidism, cardiovascular diseases (incl. with arterial hypertension).
Inside adults and children over 12 years of age appoint 1 tab. (1 mg) in the morning and evening. In cases that are difficult to treat, the daily dose can be up to 6 tab. (6 mg).
Children aged 6-12 years are prescribed 1 / 2-1 tab. before breakfast and at night.
Tablets should be taken before meals, washed down with water.
Determination of the frequency of adverse reactions: very often (≥1 / 10); often (≥1 / 100, <1/10); infrequently (≥1 / 1000, <1/100); rarely (≥1 / 10,000, <1/1000); very rarely (<1/10 000).
From the side of the nervous system: often - increased fatigue, drowsiness, sedation, weakness, fatigue, inhibition, impaired coordination of movements; infrequently - dizziness; rarely - headache, tremor, stimulating effect.
From the digestive system: rarely - dyspepsia, nausea, vomiting, gastralgia; very rarely - constipation, dry mouth; in some cases - a decrease in appetite, diarrhea.
On the part of the respiratory system: rarely - thickening of the bronchial secretion and difficulty in separating the sputum, a feeling of pressure in the chest and difficulty breathing, nasal congestion.
From the cardiovascular system: rarely - lowering blood pressure (usually in elderly patients), extrasystole; very rarely - palpitations.
From the senses: rarely - violation of the clarity of visual perception, diplopia, acute labyrinthitis, tinnitus.
From the urinary system: very rarely - frequent urination, difficulty urinating.
From the hemopoietic system: rarely - hemolytic anemia, thrombocytopenia, agranulocytosis.
Dermatological reactions: rarely - skin rash, photosensitivity.
Allergic reactions: rarely anaphylactic shock.
Symptoms: an overdose of antihistamines can lead to both depressing and stimulating effects on the central nervous system. Stimulation of the central nervous system is more common in children. Also, manifestations of anticholinergic action may develop: dry mouth,
fixed dilatation of the pupils, blood rushes to the upper half of the
trunk, abnormalities of the gastrointestinal tract (nausea, epigastric
Treatment: if a patient does not develop vomiting spontaneously, then it should be induced artificially (only if the patient's consciousness is preserved). If you take 3 hours or a little more after taking the drug, you can wash the stomach using an isotonic sodium chloride solution. You can also designate a salt laxative. Symptomatic therapy is also indicated.
Tavegil potentiates the effect of drugs that depress the central
nervous system (hypnotics, sedatives, tranquilizers),
m-holinoblokatorov, as well as ethanol.
Incompatible with simultaneous administration of MAO inhibitors.
To prevent distortion of skin scarification test results for
allergens, the drug should be discontinued 72 hours before the allergy
The tablets contain lactose, so the drug is not recommended for patients suffering from rare congenital diseases associated with intolerance to galactose, severe lactase deficiency and impaired absorption of glucose-galactose.
Use in Pediatrics
Tavegil in the form of tablets is contraindicated in children under the age of 6 years. For treatment of children aged 1 year, Tavegil can be used in the form
of a solution for intravenous and / or intravenous administration.
Impact on the ability to drive vehicles and manage mechanisms
Clemastin has a minor sedative effect (from mild to moderate in intensity), so patients who are taking Tavegil are advised to refrain from driving vehicles, working with mechanisms, as well as other activities requiring increased attention and speed of psychomotor reactions.
Pregnancy and lactemia
Contraindicated use of the drug Tavegil during pregnancy and lactation (breastfeeding).
Application in childhood
Contraindication: children under 1 year of age (tablets should not be used in children under 6 years of age).
Conditions of leave from pharmacies
The drug in the form of tablets is allowed for use as an OTC product.
Terms and conditions of storage
The drug should be stored out of reach of children at a temperature of no higher than 30 ° C. Shelf life - 5 years.