Vizomitin eye drops 5ml

Vizomitin user manual

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Composition

Drops of Skulachev (Vizomitin) contain plastoquinonyl decyltriphenylphosphonium bromide - 0.155 μg.
Excipients: benzalkonium chloride 0.1 mg, sodium chloride 9 mg, hypromellose 2 mg, sodium dihydrogen phosphate 0.81 mg, sodium hydrophosphate dodecahydrate 116.35 mg, sodium hydroxide solution up to neutral pH, water up to 1 ml.

Form of issue

Eye drops of Skulachev (Visomithin) are a transparent colorless or slightly colored liquid. 5 ml of such a liquid in a vial-dropper, one bottle in a carton.

pharmachologic effect

Eye drops Vizomitin have a keratoprotective effect.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Vizomitin was created by academician Vladimir Petrovich Skulachev.
Eye drops contain plastoquinonyl decyltriphenylphosphonium bromide (PDTF), a plastoquinone derivative containing in the structure the residues of triphenylphosphine. At low concentrations, the substance has a strong antioxidant and stimulating effect on epithelization, tearing, and increased stability of tear film.

Pharmacokinetics

Studies in the field of pharmacokinetics of the drug in humans have not been conducted. In animal studies, it was found that the distribution of PDT occurred within two days after intravenous administration. The drug was present mainly in the tissues of the liver, kidneys and heart in the first hour after administration. PDT is rapidly exposed to metabolic degradation and reaction with plasma proteins.

Indications for use

    dry eye syndrome
Often, patients give drugs unreliable effects, so recall that the effectiveness of drops Skulachev from cataracts is not proven. Studies in this direction are underway, however, it is too early to draw conclusions.

Contraindications

    allergy to any of the components of the drug;
    age is less than 18 years.

Side effects

Very rarely allergic reactions can develop.

Instructions for use Vizomitin

Instruction on eye drops Skulachev (Vizomitin) recommends instillation of the drug for the eyelid 1-2 drops three times a day. The duration of treatment is established by the attending physician and depends on the course of the disease and the severity of the symptoms.

Overdose

There are no reports of drug overdoses with local application.

Interaction

If it is necessary to apply Vizomitin simultaneously with other drops for the eyes, then the interval between instillations should be at least 5 minutes.

Storage conditions

Keep away from children. Store in a dark place in the temperature range from 2 to 8 ° C.
Open vial is recommended to store in a dark place in the temperature range from 2 to 8 ° C and use no more than 1 month from the time of opening.

Shelf life

Shelf life is one year. Use the drug after the expiration date (indicated on the package) is prohibited. The open vial should be used within one month.

special instructions

If the application of the drug causes a short-term fuzzy picture of vision, before it is fully restored it is not recommended to sit behind the wheel of a vehicle and engage in activities that require increased concentration of attention.

Children

The drug is contraindicated in persons under the age of 18 years.

In pregnancy and lactation

Controlled studies of the effect of the drug on lactating and pregnant women have not been conducted, so do not use the drug during pregnancy and breastfeeding.

Reviews about Vizomitin

Reviews of eye drops Vizomitin indicate the satisfaction of patients from the effects after using the drug. Negative reviews about Vizomitin practically do not occur, eye drops of Skulachev rarely cause allergic reactions. A number of patients report that these eye drops are effective in cataract and glaucoma, but this has not been proven by controlled studies.