Nicorette chewing gum 2mg #30

Instruction for Nicorette

You can buy Nicorette here

Composition

Chewing gum Nicorette contains as an active substance nicotine (2 mg or 4 mg). As additional substances, it contains sorbitol, Na hydrogencarbonate, Na anhydrous carbonate, glycerol, semisinteg, aromatic additive.
The Nicorette plaster contains nicotine, as well as additional substances such as acrylate copolymer, acrylic adhesive solution, medium-chain TG, croscarmellose sodium, polyethylene terephthalate film 19 μm, aluminum acetylacetonate, potassium hydroxide, polyethylene terephthalate film 100 μm.

Form of issue

The drug is available in the form of chewing gum, plaster, and also produced an inhaler Nicorette.
Chewing gum is produced with nicotine content of 2 mg and 4 mg, in packages containing 30 pads.
The patch (transdermal therapeutic system) has a surface area
10 sq. M. see, rectangular shape, rounded edges. On one side is the inscription "nicorette", the second side is sticky, white, covered with a protective film. It is produced with different amount of active substance (5 mg, 10 mg, 15 mg, 25 mg) in cartons of 7 and 14 pcs.
The inhaler includes a plastic mouthpiece and replaceable cartridges containing nicotine.
Also, sublingual tablets with lemon flavor are produced. They are round, have a white color, are flat, on one side of the tablet there is an inscription "N2".

pharmachologic effect

With withdrawal syndrome, people who abruptly abandoned nicotine-containing products, have a number of symptoms characteristic of the so-called withdrawal syndrome. This dysphoria or a bad mood, irritability, insomnia, anxiety, absent-mindedness, increased appetite, reduced heart rate.
The drug is indicated for substitution treatment in the treatment of dependence on tobacco smoking. Nicorette helps to ease the withdrawal syndrome in people who have given up smoking. This is due to the provision of the human body with ionized nicotine. But in this case in the blood plasma the level of nicotine does not have a high value.
When Nicorette's chewing gum is used, the nicotine contained in it is slowly released and slowly absorbed into the body. Systemic exposure to nicotine does not occur, as it passes through the liver quickly, it breaks down.
According to clinical studies, nicotine replacement therapy can effectively help malicious smokers to refrain from smoking.

Pharmacodynamics and pharmacokinetics

Nicotine, which enters the body from chewing gum, enters the blood after 5-7 minutes, sucked through the oral mucosa. The highest concentration of nicotine is observed 30 minutes after the chewing gum starts. Basically, nicotine is excreted by the liver, and it is also metabolized in the kidneys and in the lungs. Approximately 10-30% are excreted unchanged in the urine.
After using the patch, the maximum concentration of nicotine in the blood plasma is observed after about 9 hours. If the Nicorette plaster is applied correctly, the greatest concentration of nicotine is noted in the evening, when, as a rule, there is a persistent desire to smoke.
Nicotine binds to blood proteins by no more than 5%. In smokers suffering from chronic renal failure and receiving hemodialysis, the concentration of nicotine in the blood increases. In elderly people, the overall nicotine clearance is slightly reduced, however, dose adjustment does not require this.

Indications for use

Apply Nicorette in the following cases:
    Treatment of dependence on smoking in those who have a clear motivation for such therapy.
    Reduction in the severity of withdrawal symptoms in case a person needs to give up smoking for a certain period of time.
    Reducing the number of cigarettes smoked, if a person can not quit smoking completely.

Contraindications

Do not treat Nicorette if a person is intolerant of the substances that make up his body. Do not practice drug treatment of children.

Side effects

The intensity of side effects depends on the dose of nicotine received by a person. They are generally similar to the side effects that are observed when smoking tobacco.
Sometimes there are symptoms that are not associated with the effects on the body of nicotine, but are signs of withdrawal. These are headaches, dizziness, weakness, weakness, etc.
When using Nicorette, the following side effects are possible:
    In the functions of the intestine: nausea, vomiting, dyspepsia, hiccough.
    In the functions of the circulatory system: atrial fibrillation, tachycardia.
    Common phenomena: pain in the chewing muscles, allergic reactions, ulcers on the mucous membrane of the mouth and throat.
    Approximately 20% of people using the patch note the appearance of minor skin local reactions in the first days of treatment.

Instructions on Nicorette (Method and dosage)

The following rules must be carefully observed in order to achieve the desired effect.
Instructions for the use of chewing gum are as follows: Initially chewing gum Nicorette 2 mg is taken. Every day 8-12 gum pads are taken. If the smoker has a heavy dependence on tobacco smoking (previously he smoked from 20 cigarettes per day), it is desirable to apply for replacement therapy Nicorette 4 mg. A day can chew no more than 24 chewing gum.
If a person wants to quit smoking completely, he needs to apply chewing gum for at least 3 months, after which the dose gradually decreases. When the dose will be 1-2 pads per day, the drug can be canceled.
Chewing gum is recommended to chew every time when there is a strong desire to smoke. If using such a regimen for a month and a half the amount of cigarettes smoked does not decrease, the tactics of treatment should be changed.
Nicorette tablets are used sublingually and kept until completely dissolved. Dosage is selected individually. People with a low dependence on a single dose just take one 2 mg tablet, people with severe dependence can increase the dose to two 2 mg tablets. A day can not eat more than 30 tablets of 2 mg.
The instruction for the Nicorette plaster is as follows. In the morning it is applied to intact skin, remove the patch before bed. Accordingly, during sleep, nicotine does not enter the body. At the first stage, a 25 mg patch is used per day. This stage lasts 8 weeks. Further for two weeks you need to use a patch 15 mg. For the next two weeks, a 10 mg patch is already used.
If nicotine dependence is not strong, treatment begins with the use of a 15 mg patch (treatment lasts 8 weeks). The next four weeks apply a 10 mg patch.
Treatment lasts about 3 months on average. Sometimes a longer period is required, but it is not recommended to use a patch without a break for more than six months.
The patch is glued on a dry and clean skin without a hair covering (thigh, chest, shoulder). Every day you need to change the place for the application.
Before gluing, you should wash your hands, cut the package and gently glue the patch, trying not to touch the sticky surface.

Overdose

With an overdose of Nicorette, the same symptoms are observed as in nicotine poisoning:
    nausea;
    headache and dizziness;
    abdominal pain and stool disorders;
    hyperhidrosis;
    hypotension, weakness;
    arrhythmia;
    labored breathing;
    the appearance of seizures.
It should be noted that therapeutic doses intended for adults can be lethal for young children.
Smoking and concurrent use of Nicorette may lead to an overdose of nicotine. Overdose is possible with the use of several patches at once, as well as with the simultaneous application of different forms of Nicorette.
When an overdose immediately stops using nicotine and symptomatic therapy is performed.

Interaction

Due to the cessation of smoking, the blood concentration of a number of drugs may increase: clozapine, theophylline, flecainide, imipramine, and other drugs with a low therapeutic index.
There is evidence that when smoking can change the metabolism of flecainide and pentazocine.

Terms of sale

You can buy Nicorette without a doctor's prescription.

Storage conditions

Nicorette should be protected from children, the drug should be stored at a temperature of 15 to 25 degrees Celsius.

Shelf life

Chewing gum Nicorette can be preserved for 2 years, tablets - 3 years, plaster - 3 years.

special instructions

When treating chewing gums, people with removable dentures may experience discomfort and discomfort. If Nicorette is used by people suffering from cardiovascular diseases, their condition should be strictly controlled by the attending physician.
The drug is administered with caution to people with liver and kidney disease, patients with peptic ulcer, hyperthyroidism, pheochromocytoma.
If the insulin-dependent diabetic patient refuses smoking, he needs to adjust the dose of insulin taken.
If you refuse to smoke, a person can gain weight. With the use of Nicorette, this process can be taken under control.
If there is a need to stop smoking for a certain time, then the drug is taken immediately after the desire to smoke.
There is no negative impact on the ability to drive vehicles or work with precise mechanisms.

Children

Experience in the treatment of Nicorette children and adolescents under 18 years is absent, so its use is not practiced for children.

With alcohol

When treating Nicorette, it is undesirable to take alcohol, as well as energy drinks.

In pregnancy and lactation

To date, the negative impact of the drug on the fetus has not been sufficiently studied. There is evidence that the drug may have a negative effect on the respiratory and cardiovascular systems of the fetus. Nicotine is able to penetrate the placenta, it is excreted in breast milk, so it can be dangerous for the fetus or the baby.
If attempts to quit smoking without replacement therapy in pregnant women prove unsuccessful, the expected benefits of using the drug for a woman and the risk for a fetus are compared.
When feeding, nicotine can get into the milk, so the mother can take Nicorette no later than two hours before the start of feeding.
More detailed information about the preparation is given by the official site: nicorette.ru or nicorette.ua.

Reviews about Nicorette

There are different opinions about the treatment with this remedy. But basically reviews about the Nicorette patch and reviews about the chewing gum of Nicorette are positive, as many people this drug really helps get rid of bad habits. Judging by most reviews, the opportunity to quit this habit with the help of Nicorette from the experience of smoking does not depend. Smokers also note that the plaster from smoking is more convenient to use than tablets or chewing gum.
If you read the reviews of doctors on chewing gum from smoking, then it follows that the chewing gum helps to reduce the number of cigarettes smoked a day.
Nevertheless, those who are looking for detailed reviews about this drug, are mainly interested in whether the Nicorette plaster helps to quit smoking?
Former smokers note that the first course of treatment of Nicorette from dependence is easier to get rid of than with the treatment of Nicorette after the repeated return of the habit of smoking. In most cases, when treated with a drug, there is a much lower dependence on the desire to smoke.
People who leave feedback point out that Nicorette plaster reduces the tendency to smoking almost from the first day of use. It is important to carefully consider contraindications, know how to choose the patch correctly, and how to use it during the treatment. It is necessary to study the instruction, from which you can find out how many pieces in the adhesive package can be, where to paste the adhesive, whether it is possible to smoke with a patch, etc. Very important is the 1 stage of treatment, so during this period it is necessary to follow instructions very clearly.
In the reviews, there are also some side effects that develop during treatment. This is a headache, redness of the skin at the places of use of the plaster, changes in appetite, etc. However, doctors say that the majority of the symptoms are due to the rejection of cigarettes or a decrease in their number. In addition, people who used Nicorette, note that treatment with the drug helps in the process of quitting smoking to maintain a normal weight.