Vermox tabs 100mg #6

Vermox user manual

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Composition

To 1 tablet of 100 mg of mebendazole.
Sodium lauryl sulfate, magnesium stearate, silicon dioxide, sodium saccharinate, starch, lactose monohydrate, talc, as excipients.
A 5 ml suspension of 100 mg of mebendazole.

Form release

Suspension 2%.
Tablets 100 mg.

Pharmacological action

Anthelmintic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

An anthelmintic drug with broad spectrum of action. High efficiency is noted in enterobiasis, ascariasis and trichocephalosis. Primarily acts on the energy processes of the parasites. Causes a violation of glucose consumption, ATP synthesis, depletes glycogen reserves. Selectively inhibits the synthesis of β-tubulin of muscle cells of helminths, which leads to their paralysis and disruption of transport systems.
Detrimental effect on eggs of Ascaris, hookworm. In high doses it is used for the treatment of trichinellosis and echinococcosis — extracurricular helminthiasis. The drug is well tolerated.

Pharmacokinetics

Almost not absorbed in the intestine. 90% of proteins associated with blood. The half-life period is from 2.5 to 5 hours. Accumulates in larvae of helminths, liver and adipose tissue. Metabolized in the liver. About 5-10% of the drug is absorbed and then excreted by the kidneys. More than 90% is excreted with feces.

Indications for use

hookworm disease;
strongyloidiasis;
enterobiasis;
ascariasis;
trichocephalosis;
taeniasis;
trichinosis;
alveococcosis;
echinococcosis;
capillariasis;
mixed helminthiasis.

Contraindications

liver failure;
ulcerative colitis;
hypersensitivity;
the age of 2 years;
Crohn disease;
pregnancy and breast-feeding.

Side effect

abdominal pains;
dizziness;
nausea.
When applying high doses for a long time:
vomiting, upset his chair;
headache;
rash, Quincke edema;
hair loss;
creatinine level increase;
hematuria and cylindrical;
increased activity of liver enzymes;
leukopenia, eosinophilia, anemia.

Pills Vermox, usage instructions (Method and dosage)

Tablets are taken orally. How to take Vermox: before or after a meal? Tablets are taken after meals.
Adults and children from 10 years with identified enterobiosis appoint once 100 mg.Children from 2 to 5 years 25 mg once, from 5 to 10 years 50 mg once. All family members are being treated. When a high probability of re-invasion is repeated after 2 weeks in the same dosage.
Ascariasis, hookworm, teniasis, trihozefaleze, strongyloidiasis and mixed helminthiasis take twice a day 100 mg 3 days in a row.
With trihinelleze three times a day for 200-400 mg 3 days in a row, from 4 days the dose is increased by 400-500 mg three times a day and taken until the 10th day.
Instructions for use Vermox contains a warning that the day after taking the tablets can not drink alcohol, fatty foods, take a laxative. After the end of treatment, it is necessary to examine the smears and feces for 7 days for the presence of helminths and their eggs. With long-term treatment, it is necessary to monitor liver and kidney function, blood analysis.

Overdose

Manifests itself symptoms: pain in his stomach, vomiting, diarrhea, vomiting.
In the treatment of high doses of long-term hepatitis, transient disorders of liver function, neutropenia.
Treatment starts with gastric lavage, appointment of adsorbents, symptomatic therapy if necessary.

Interaction

Simultaneous intake of Cimetidine increases the concentration of mebendazole in the blood, lowers Carbamazepine.
Mebendazole reduces the need for insulin in diabetes.
Avoid co-administration of lipophilic substances.

Terms of sale

To buy Vermox the prescription is not needed.

Storage conditions

At a temperature not exceeding 30 C.
Shelf life - 5 years.

Vermox for children

The most common diseases in children are ascariasis, enterobiasis and giardiasis. The peaks of these parasitic diseases have for 2-3 years, 4-7 years and 10-14 years, which is due to enzymatic insufficiency, disturbance of acid-alkaline gradient in the gastrointestinal tract, the normal microflora and motility. The period after intestinal infections in children, as well as after antibiotic therapy is more vulnerable to infestation.
With ascariasis, the effectiveness of the drug is 100%. Vermox for children is used in age doses: 2-10 years take 0.05 g / day, divided into 3 admission, 10 years — 0.1 g per day for 3 admission. Treatment for 3 days.
In enterobiosis (infection with pinworms) treatment is carried out one day: from 2 to 5 years 1 / 4 tablets once, from 5 to 10 years 1 / 1 tablet, older than 10 years 1 tablet. It is mandatory to re-take the drug in the same dose after 2 weeks. It is also recommended to stretch the underwear at a high temperature (90C) of all family members
How do worms come out? They die and on next day in feces can be discern immobilized parasites. Worm infestation in children causes functional disorders of the digestive system, the change in the microbiota and enzyme defect. In this connection, after the course of deworming children appoint courses of enzyme preparations and synbiotics (Bifiform, Normoflorin) multivitamin. Such comprehensive treatment prevents the appearance of organic pathology of the gastrointestinal tract and prevents reinvasion.
Reviews about the drug positive-it rarely caused side effects. Some of the children had diarrhoeal phenomenon, pain in the abdomen, headache. There was also a deterioration in the skin of children with dermatitis. This is due to the fact that the death of helminths is accompanied by the release of toxins. This is why chelators are assigned in parallel to 2 hours after administration of the drug. During treatment, you should also monitor the timely emptying of the intestine. When constipation increases intoxication due to the death of parasites, especially with intense worm invasion. If there is no natural evacuation you need to put an enema.
Many parents give this drug to children for prevention at the end of the summer after a holiday in the country or in the village at the grandmothers, when the most likely infection when eating unwashed vegetables and fruits, through dirty hands and after contact with animals. Is that justified? If there are no complaints from the child, nothing should be given for prevention. In some cases, the appointment of anthelmintic means are justified, even without a survey. But not for the purpose of prevention, and when there is clinical symptoms characteristic of an invasion, and laboratory is not confirmed. Self-medicating better not engage. The right approach - first laboratory study, even 10 times, and then treatment, which is different timing and choice of the drug depending on the type of parasite.
You should know that the drug causes increased motor activity of worms, sometimes this leads to antiperistaltic, vomiting and reflux of ascarids in the respiratory tract. Therefore, in case of intensive infestation in children, it should be used with caution.

Reviews Vermox

Vermox pills what are they for? It's an anthelmintic. The drugs based on mebendazole (Vermin, Vermox) and albendazole (Worm, Nematol) act on the energy processes of worms and have a wide range of action, containing Levamisole (Dekaris) disrupt the function of the neuromuscular system and destroy round worms. Based on this, the first group of drugs is more effective, especially if you can not determine the type of helminth. Vermox tablets from worms are effective, they are prescribed to adults and children. This is confirmed by the forum on this topic. They were taken at the first symptoms of invasion (anal irritation and itching), and again after 14 days. It was often used for prevention by all family members.
Treatment of ascariasis and enterobiasis with this drug is effective in all children and adults. This is confirmed by reviews Parasitologists about Vermoxe. During these invasions achieved 100% deworming, when hookworm — 91%, the teniasis — 80%, strongyloidiasis — 67%. They believe that this drug is Pyrantel effective when enterobioze, but much more toxic. In this regard, it can not be used "just in case", oseltamivir, especially in children. If you want to do this, it is better to use the Girantel. Vermox from worms particularly indicated in cases of preinvasive and rare invasions, for example, hydatid disease. The methods of conservative treatment of this disease long-term multi-month use of high doses of the drug-courses of 30 days in increasing doses up to 600 mg per day or more.
Reviews Vermox for children in most cases positive. Administered to children from 2 years. Parents noted that in the course of treatment there was a rapid improvement: allergic reactions completely disappeared, abdominal pain immediately stopped, the work of the gastrointestinal tract normalized. The criteria for the effectiveness of treatment is the disappearance of clinical symptoms and a negative result of research — feces (with ascariasis) and scraping (with enterobiosis). Negative reviews are related to the presence of adverse reactions, which are rare: disorder of the chair and abdominal pain. Remember that this drug should be prescribed to children by a doctor after the examination, the reception of enterosorbents during treatment and timely evacuation of the intestine is obligatory.
Before application of the drug is necessary to study contraindications. It can not be used in peptic ulcer diseases of the intestine, as it is possible to increase absorption into the blood, anemia, liver dysfunction, pregnancy and breastfeeding. Remember that fats enhance absorption and possible toxic effects. With prolonged use of the drug may increase the temperature, headache, vomiting, rash, and when taking high doses-hair loss.