Carnicetine caps 295mg #60

Carnicetine instruction

Reed more and buy Carnicetine online

Composition

Acetylcarnitine hydrochloride, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate, gelatin, titanium dioxide.

Form of issue

Hard gelatin capsules 295 mg, white in a blister pack of 10 or 15 pieces in a cardboard bundle or in a polymer jar in cardboard pack No. 60.

pharmachologic effect

Antioxidant, metabolic, neuroprotective, cholinomimetic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

In physiological conditions the biologically active substance acetyl-L-carnitine is an integral component of various tissues and organs of the human body, takes an active part in the metabolism of carbohydrates and fatty acids.
It is the metabolic effects of acetyl-L-carnitine (ALA) and its constituent acetyl group that determine its pharmacological effect, since it is the active form of L-carnitine, which is of major importance in the process of fat catabolism and, as a result, the formation of energy in the body. ALA under the influence of the enzyme carnitine acetyltransferase is synthesized from L-carnitine in the liver, brain tissue and kidneys. Since ALA supplies the activated acetate directly to the mitochondrial matrix for the synthesis of acetyl CoA, which takes part in the cycle of tricarboxylic acids, without increasing the energy expenditure, it is an accessible substrate for the initiation of metabolic processes in the mitochondria. As a result of a full-fledged supply of energy to the body while reducing tissue oxygen consumption, ALA protects against cerebral ischemia.
ALA has a structural similarity with acetylcholine, due to which it has a cholinomimetic and neuroprotective effect. Increases the concentration of glutamine, aspartic acid and taurine in cells, with prolonged use increases the density of N-methyl-D-aspartate receptors in the hippocampus, striatum and cerebral cortex, inhibits the processes of reducing their density during aging. ALA protects the brain cells from the neurotoxic action of glutamate and ammonia, enhances the action of serotonin.
ALA has anamnestic effects, improves the effectiveness of training, improves non-associative memory, positively influences mnestic functions in Alzheimer's disease, while there is no sedative and muscle relaxant action.
ALA contributes to the enhancement of energy production, stimulates the synthesis of phospholipids and proteins to build membranes, normalizes regeneration processes. It has a neuroprotective effect, in particular, with respect to neurons and organelles (mitochondria) and due to activation of the nerve growth factor has a neurotrophic effect. Has a membrane-stabilizing and antioxidant effect, with endocrine and traumatic damages of the peripheral nerves accelerates the regeneration of nerve cells. ALA has a pronounced effect on aging processes, slowing them by increasing the transport in the mitochondria of fatty acids and maintaining their function at the level of the young organism.

Pharmacokinetics

The maximum concentration of Carnicetine in the blood is observed 4-5 hours after taking the drug. Absorption from the gastrointestinal tract is carried out by diffusion through the mucous membrane (with or through active transport.In the tissue, the ALA organism enters unchanged from the bloodstream (with the exception of the liver and small intestine), and directly into the cell - due to an energy-dependent direct process against the concentration gradient It is excreted from the body with urine.

Indications for use

In the complex treatment of Alzheimer's disease, peripheral neuropathy, cerebral vascular dementia, involution syndromes that occur against the background of vascular encephalopathies, and reduce mental capacity.

Contraindications

High sensitivity to the drug, lactation, pregnancy, age of 18 years.

Side effects

Local allergic manifestations, heartburn, nausea.

Carnicetine, instructions for use (Method and dosage)

Carnicetine capsules are taken orally without binding to meals. Recommended single dose for adult patients: from up to 4 capsules, daily - 6-12 capsules. Instructions for the use of Carnicetine indicates the need for long-term use of the drug (1-4 months).

Overdose

There are no reliable data on the overdose of Carnicetine.

Interaction

Clinical symptoms in the interaction with other drugs have not been identified.

Storage conditions

At a temperature of 15-25 ° C.
After you bought Carnicetine online, you should store it not more then 24 months

Reviews about Carnicetine

Among the majority of patients taking the drug, reviews about Carnicetine are favorable.
"... Stroke suffered, speech was severely affected and memory worsened. In addition to special drugs, the doctor recommended taking Carnicetine. I drank it on the capsule three times a day for almost three months. The effect is good. Speech has greatly improved, I began to recall past events. I recommend this drug to everyone who is in the same situation. "