Donormyl 15mg #30

Instruction for Donormyl

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The drug Donormyl belongs to the group of hypnotic medicines and is prescribed to patients with sleep disorders and insomnia.

Form of formulation and composition of the preparation

The drug Donormyl is available in the form of tablets for oral administration and in the form of effervescent tablets for solutions in water.
Tablets for oral use are available in tubes of 30 pieces, covered with a protective film shell.
Effervescent tablets of large size, round, packed in tubes of 10 pieces in a cardboard box with the attached instructions. The pack contains 2 tubes of 10 tablets.
The main active ingredient of the drug Donormyl is doxylamine succinate - 15 mg in 1 tablet. Also in the composition of the preparation are auxiliary components: lactose monohydrate, microcrystalline cellulose, magnesium stearate.

Pharmacological properties of the drug

Donormyl belongs to the group of H1-histamine receptor blockers. Upon admission, they enter into an active substance, which can be absorbed into the systemic bloodstream through the mucous membranes of the food canal and exerts a pronounced hypnotic, sedative and m-holin-blocking effect. The drug normalizes night sleep, shortens the duration of sleep, improves sleep quality. The therapeutic effect develops after 15 hours. After awakening, the patient does not feel lethargic and tired, as is often the case with the use of sleeping pills.

Indications for use

Donormyl tablets appoint patients 14 years old to solve problems with falling asleep of various origins.

Contraindications

Before starting therapy with the drug, the patient should read the attached instructions in detail, since the medicine has the following contraindications and limitations to use:
Individual intolerance to the components of the product;
Lactase insufficiency;
Closed-angle glaucoma;
Impaired renal function, in particular, urinary retention;
Age to 14 years.

With special care, Donormyl tablets are administered to patients under the following conditions:

The history of respiratory arrest in sleep;
Age of patient is over 65;
Hepatic or renal insufficiency;
Pregnancy period (1st and 3rd trimesters);
Breastfeeding period.

Method of administration and trial preparation

Donormyl is intended for oral administration. The drug takes only once before bed. A tablet in a film shell is swallowed without chewing, and washed down with a small amount of water. The effervescent tablet must first be dissolved in half a glass of water, wait until there are no suspensions.
The initial dose is ½ tablet (both normal and effervescent). If the effect is not observed, then the dose is increased to 1-2 tablets according to the doctor's recommendation. The duration of the course of therapy is determined by the doctor, but do not take Donormyl tablets for more than 5 consecutive days. If there is no therapeutic effect with a dose of 2 tablets, treatment should be discontinued and consult a doctor again.

Use of the drug during pregnancy and lactation

The drug Donormyl is not recommended for the treatment of insomnia in women in the first trimester of pregnancy, because during this period the embryo is laid down all organs and systems, and the influence of medicinal components can disrupt this process.
The use of the drug in the second trimester of pregnancy is possible under the supervision of a doctor. Conducted medical studies have not revealed abnormalities in the development of the child on the background of the use of Donormyl by a woman during pregnancy.
The use of this drug in the third trimester of pregnancy is possible after assessing the indicators of benefit to the mother and the possible risk to the fetus. For newborns, whose mother Donormyl received in the last weeks of pregnancy, medical control is established, since it is possible to suppress the central nervous system in the child.
It is not known whether the active substance of the drug Donormyl penetrates into breast milk, so if necessary, the lactation of nursing mothers should be discontinued.

Side effects

In most cases, the drug is well tolerated by patients. With increased individual sensitivity, the following side effects may develop:
    Dryness of the mucous membranes of the oral cavity;
    Increased thirst;
    Constipation, stomach pain;
    Increased heart rate;
    Violation of the reaction to what is happening around;
    Drowsiness, weakness and lethargy;
    Retention of urine;
    Dizziness and loss of balance (especially important for elderly patients).

Overdose of the drug

When taking too large doses of the drug, the patient develops the following signs of an overdose:
    Lethargy in the daytime, disorientation in space;
    Drowsiness and inhibition of reaction;
    Dry mouth;
    Hyperemia of the face;
    Changing the rhythm of the heart;
    Increased body temperature;
    Mental disorder, irritability;
    Tremor of limbs;
    Severe vertigo until loss of consciousness;
    Decrease in blood pressure indicators;
    Convulsions;
    In rare cases, the development of coma is possible.
In addition, patients may develop renal or hepatic insufficiency and general poisoning of the body.
When developing signs of an overdose, the patient should immediately consult a doctor. Treatment consists in washing the stomach, ingesting enterosorbents and performing symptomatic treatment if necessary.

Interaction of the drug with other drugs

With the simultaneous use of the drug Donormyl with sedatives, tranquilizers, antipsychotics, antidepressants, the therapeutic effect of the hypnotic and depressing effect on the central nervous system is enhanced.
When the drug Donormyl is combined with drugs from the group of m-holinoblokatorov (atropine, disopyramid and others), the risk of side effects such as constipation, weakness, urinary retention, dry mouth increases.
With simultaneous use of the drug with drugs, which include ethanol, the risk of toxic damage to the central nervous system and the liver increases.

special instructions

The drug with extreme caution should be prescribed to patients with impaired respiratory function!
It should be understood that insomnia can be caused by causes that do not require treatment with the drug, for example, when taking a lot of caffeine or when psychoemotional overexcitation.
Since the tablet contains lactose in patients with lactase deficiency, this drug is not prescribed.
Against the backdrop of treatment with Donormyl, patients can inhibit the speed of psychomotor reactions and inhibit the central nervous system, so at this time it is not recommended to drive and complex mechanisms that require the patient to increase concentration.
The drug is administered with caution to people over 65 years of age due to the likelihood of developing dizziness and the risk of losing balance as a result.

Conditions of drug storage

The drug Donormyl is dispensed in pharmacies without a prescription. Keep the tablets out of the reach of children at room temperature. Do not allow moisture to enter the product.
The shelf life of the tablets is indicated on the package, at the end of the medicine it is not allowed to take it inside.