Enerion tabs 200mg #60

Enerion instruction

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Composition

One tablet includes 200 mg of sulbutiamine as the active ingredient.
Additional ingredients: 9 mg - talc, 12 mg - corn starch, 20 mg - anhydrous glucose (dextrose), 40 mg - dried starch paste, 3.5 mg - magnesium stearate, 65.5 mg - lactose monohydrate.
The composition of the shell: 28.21 mg - talc, 0.603 mg - sodium hydrogen carbonate, 0.201 mg - white beeswax, 0.556 mg - sodium carboxymethylcellulose, 8.43 mg - titanium dioxide (E171), 3 mg - Sanseeta yellow (E110), 0.485 mg - ethylcellulose, 0.242 mg glycerol monooleate, 0.692 mg povidone, 0.302 mg polysorbate 80, 0.404 mg anhydrous colloidal silica dioxide, and 106.956 mg sucrose.

Form of issue

The drug Enerion is available in the form of tablets in a shell, 20, 30 or 60 pieces per pack.

pharmachologic effect

Metabolic.

Pharmacodynamics and pharmacokinetics

The drug Enerion is a synthetic compound that is close in structure to thiamine and is distinguished from it by the open thiazole cycle of the molecule, a lipophilic ester and an additional disulfide bond.
Due to its structure, sulbutiamine has good solubility in fats, easily passes through the blood-brain barrier and is quickly absorbed into the digestive tract.
Unlike thiamine, sulbutiamine accumulates in the dentate gyrus, the hippocampus, the cellular structure of the reticular formation, the glomeruli of the granular layer of the cerebellar cortex, Purkinje cells.
The use of Enerion improves motor coordination and increases the body's resistance to physical exertion, increases the resistance of the brain to oxygen deficiency. The drug is especially effective for symptomatic therapy of functional asthenia.
When taken orally, the sulbutiamine is absorbed rather quickly in the digestive tract. Cmax in the blood is observed after a lapse of 60-120 minutes. T1 / 2 approximately 5 hours, excreted by the kidneys.

Indications for use

The drug is intended for the treatment of symptoms of functional asthenia.

Contraindications

Hypersensitivity to sulbutiamine or other ingredient, both tablets and her shells.
With caution should be given to persons under 18 years of age, due to the lack of experience of use at this age.

Side effects

Psychoneurological complications: headaches, tremors, agitation, a feeling of general malaise.
Allergic skin manifestations (most often due to the presence of the dye shell - E110 "Yellow sanset").
Various dyspeptic disorders of the digestive tract.

Instructions for the use of Enerion

Instruction for Enerion recommends its use only by adult patients. Tablets are taken orally (by mouth) with water.
Usually the daily dose of sulbutiamine is 400-600 mg (2-3 tablets).
Tablets are best taken twice a day during meals (breakfast and lunch). The maximum possible time for the therapy is 30 days.

Overdose

Symptoms of an overdose of Enerion tablets are manifested by tremors of limbs, excitement, a state of euphoria.
Most often this symptomatology is of a transitory nature and therefore does not need special therapy.

Interaction

To date, the drug interaction of sulbutiamine with other drugs has not been described.

Storage conditions

The temperature of storage of tablets is up to 25 ° С.
Shelf life - 36 months from the date of manufacture.

special instructions

One of the additional ingredients of the drug is lactose monohydrate, and therefore, it is not recommended for administration to people with galactoseemia, lactose deficiency, or glucose / galactose malabsorption syndrome.

Children

Experience in the use of sulbutiamine before the age of 18 years is not available, so it is not recommended for patients of this age category.

In pregnancy and lactation

According to the results of the research, the drug does not affect the development of the fetus, but due to lack of experience in clinical use is not recommended for use during pregnancy.
At this time, the penetration of sulbutiamine into the mother's milk has not been established for sure, therefore, it is not recommended to take it during breastfeeding.

Reviews about Enerion

In 90% of cases, reviews about Enerion, left by people taking this drug, are positive.
According to their assessment, the drug perfectly copes with such symptoms of asthenia as: anxiety, irritability, fatigue, anxiety, lethargy and other manifestations, the cause of which is the constant mental and physical stress of modern man.
Some sources in general claim that the Enerion drug is the only anti-asthenia, with a proven effectiveness and mechanism of action, and note the practical absence of side effects of the drug.
For the sake of justice, it should be noted that there are a number of people who do not fit this medication and do not bring relief to their morbid condition, but at the same time it does not cause any negative phenomena, which in our time is also important.