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Aromasin tabs 25mg #30

  • $67.73
  • 2 or more $66.99
  • 3 or more $66.50
  • Availability:In Stock

Aromasin user manualReed more and buy Aromasin on this pageCompositionThe drug has an active substance exemestan and additional components: mannitol (E421), sucrose, titanium dioxide (E171), microcrystalline cellulose, hypromellos..

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Aromasin user manual

Reed more and buy Aromasin on this page


The drug has an active substance exemestan and additional components: mannitol (E421), sucrose, titanium dioxide (E171), microcrystalline cellulose, hypromellose, crospovidone, sodium starch glycol, polyvinyl alcohol, magnesium carbonate light, macrogol 6000, magnesium stearate, silicon dioxide colloidal aqueous, Polysorbate 80, methyl parahydroxybenzoate, emulsion simeticone.

Form release

Aromasin available in tablets which covers sugar-coated. This round biconvex white tablets with a grayish hue.
On one side of the tablet there is a black marking in the form of a number "7663". The package can hold 15, 30 or 90 tablets.

Pharmacological action

Aromasin is an irreversible steroidal aromatase inhibitor, which is structurally reminiscent of a natural substance Androstenedione.
In the body of a woman who is experiencing a period of postmenopausal estrogen production passes mainly through the conversion of androgens into estrogens under the influence of the enzyme aromatase. By blocking the production of estrogens through aromatase inhibition, it is possible to provide effective treatment of hormone-dependent breast cancer in women during postmenopause.
Means Aromasin acts by binding the active substance to the active fragment of the enzyme. As a result, it is inactivated. Aromasin is influenced by the concentration of estrogen in the blood of postmenopausal women decreases. This process is noted when taking a dose of 5 mg, the most pronounced decrease is observed when taking doses of 10-25 mg.
According to available studies, in women in this category who received 25 mg of the drug daily, the enzyme aromatase decreased by 98%.
Exemestane does not demonstrate progestogenic and estrogenic activity. If the tool is used in high doses, marked his slight androgenic activity.
The drug does not affect the biosynthesis of aldosterone and cortisol in the adrenal glands, which confirms its selective effect. In this regard, there is no need for replacement therapy with glucocorticoids and mineralocorticoids.

Pharmacokinetics and pharmacodynamics

Once exemestane gets inside, it is absorbed from the digestive tract quickly. There is no data on the absolute bioavailability of the product. If a dose of 25 mg was taken once, the maximum concentration in plasma is noted after 2 hours.
If the patient simultaneously with the medication takes food, the bioavailability is increased by 40%. Exemestane binds to plasma proteins by 90%. The active substance of the drug and its metabolites do not bind to erythrocytes
The half-life of the organism is about 24 hours. Approximately 40% of exemestane is excreted during the week with feces and urine.
There is no connection between the age of a person and the systemic effect of the drug. Do not adjust the dose to those who suffer from kidney or liver failure.

Indications for use

Aromasin is indicated for use in the following cases:
For the purpose of adjuvant treatment of postmenopausal women who have early stages of breast cancer, the sample for estrogen receptors, unspecified or positive. It is used to reduce the manifestation of local regional, distant or contralateral metastases.
Assigned as the cure of the first row for the treatment of carcinoma of the breast in women with induced or natural status of a menstrual pause, in which there is a positive test for hormone receptors.
It is prescribed as a second-line drug for the treatment of common breast cancer in patients with a natural or induced postmenopausal status, provided that they have marked the progress of the disease against the background of monotherapy with antiestrogens.
Prescribed as the medicine of the third row with the aim of therapy carcinoma of the breast in patients experiencing a menstrual pause, provided that they have marked the progress of the disease on the background oligomannose treatment.


Aromasin is not prescribed for the development of high sensitivity to exemestane or other substances that are part of the means.
Also not prescribed to pregnant women, nursing mothers and patients in childhood.

Side effect

The drug during therapy is well tolerated by patients. However, sometimes there are moderate or weak manifestation of side effects.
Women who took a course of treatment with Aromasin, as side effects often noted the appearance of the tides, the high fatigue and arthralgia. Thus, when taking the drug, the following side effects were noted:
metabolic disorders: anorexia;
mental disorders: insomnia, depression;
vascular disorders: hot flashes;
neurological disorders: dizziness, headache, drowsiness;
disorders in the gastrointestinal tract: nausea, abdominal pain, vomiting, diarrhea, constipation, dyspepsia;
skin disorders: severe sweating, alopecia, rash;
disorders of the musculoskeletal system: back pain, muscles, joints, limbs, osteoarthritis, myalgia, arthritis, fractures, osteoporosis;
lymphatic system, circulatory system: thrombocytopenia and leukopenia in people with advanced breast cancer;
other disorders: peripheral edema, fatigue, asthenia.
There was also an increase in functional liver tests.

Manual for Aromasin (Method and dosage)

Manual of Aromasin provides that adult women and patients in older age should take tablets once daily in the dose of 25 mg 1 time per day. It is recommended to drink the medicine after eating.
In early stages of breast cancer, Aromasin should be taken until the end of five-year adjuvant hormone therapy or before the appearance of distant or local or new contralateral tumor.
Patients suffering from advanced cancer of the breast should continue therapy until such time as progress of the tumor.


There is no evidence of a single dose of this drug that could cause serious symptoms.
If there was an overdose, it is necessary to carry out symptomatic treatment, as there is no specific antidote.


Aromasin should not be prescribed with those drugs that contain estrogen, as at simultaneous reception had negative pharmacological effects.
The active ingredient does not inhibit any of the major CYP isoenzymes, is metabolized under the influence of cytochrome P450 (CYP3A4) and aldoketoreductase.

Terms of sale

To buy Aromasin the prescription is not required.

Storage conditions

Refers to list B. Should be stored at a temperature that does not exceed 30°C, Aromasin should be protected from access by children.
Shelf life - 3 years. After this period, you can not take pills.

Special instruction

It is not prescribed to patients with premenopausal endocrine status, given the mechanism of influence of this drug. You need to set the status by assessing the levels of FSH, LH, estradiol.
As Aromasin is a tool under the action of which considerably reduces the estrogen level, you should expect that bone mineral density will decrease.
If necessary, adjuvant treatment of people with osteoporosis or those who have a risk of developing this disease, it is initially necessary to evaluate the parameter of bone mineral density by densitometry.
It is important to provide constant supervision for those who take Aromasin, if there is such a need, patients should undergo treatment of osteoporosis.
Patients should consider, that in the composition of the Aromasin there is sucrose.
Due to its composition of tablets metilparagidroksibenzoat, patients may develop allergic reactions, sometimes topstitched.
Since the development of asthenia, drowsiness, dizziness is possible in the process of taking this medicine, it should be taken into account by people who manage transport and those who are engaged in potentially unsafe activities.
Athletes sometimes use Aromasin in bodybuilding, to prevent the increase in the content of estrogen after taking a course of steroids and, as a consequence, the development of gynecomastia.


Not used for the treatment of children.

Pregnancy and lactation

It is contraindicated in pregnant women and women taking Aromasin during natural feeding, as in the study of the drug in animals was noted reproductive toxicity.

Reviews of Aromasin

Leaving reviews of Aromasin, patients noted that the drug is well tolerated, but sometimes there are side effects as nausea, pain in the joints and back, insomnia, hot flashes.
There is a positive effect of this drug on the body in the development of Oncology. But women write that to take this medicine should only be under the strict supervision of a doctor.

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