Bicalutamide tabs 150mg #30
- $85.48
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Instruction for BicalutamideReed more and buy Bicalutamide on this pageCompositionBicalutamide, corn starch, croscarmellose sodium, lactose monohydrate, sodium fumarate, povidone, polyvinyl alcohol, Opadry white, polyethylene glyc..
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Instruction for Bicalutamide
Reed more and buy Bicalutamide on this page
Composition
Bicalutamide, corn starch, croscarmellose sodium, lactose monohydrate, sodium fumarate, povidone, polyvinyl alcohol, Opadry white, polyethylene glycol, titanium dioxide, talc.
Form release
Tablets of 50 and 150 mg biconvex film-coated 14 pieces in a blister pack in a cardboard bundle number 28, 280.
Pharmacological action
Antitumor, anti-androgen.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Bicalutamide — medication with non-steroidal antiandrogenic activity, not with other endocrine activity. Binds to androgen receptors and inhibits the stimulating effect of androgens, while gene expression is not activated. These processes cause the regression of malignant neoplasms (cancer) of the prostate.
Pharmacokinetics
Completely and quickly absorbed into the digestive tract, while the food on the suction process has no effect. The relationship with the squirrels reaches 96%. Metabolized in the liver, T 1/2 metabolite is about a week. It is excreted in the form of metabolites with bile and urine.
Indications for use
Monotherapy and as part of the General therapy of patients with prostate cancer, both in combination with radiotherapy or radical prostatectomy of the non-metastatic malignant process, and patients who have not undergone radiotherapy or radical prostatectomy.
Contraindications
Individual hypersensitivity, childhood, co-administration with Terfenadine, Cisapride, Astemizole, lactase intolerance or deficiency, women.
Side effect
Some patients may experience gynecomastia and breast pain, skin itching, jaundice, tides, nausea, diarrhea, vomiting, headache, dizziness, increased drowsiness or insomnia, asthenia, shortness of breath, heart failure, chest pain and pelvic pain.
Instruction for Bicalutamide
For adults a single oral dose of 50 mg per day in combination with surgical castration or an analogue LGRF.
In the absence of metastases of prostate cancer for the treatment of malignant process without the appointment of other drugs or surgical castration — once 150 mg per day.
Instructions for use indicates the need for long-term administration of the drug (at least 2 years), at the same time, in the presence of pronounced impairment of liver function requires dose adjustment.
Overdose
No data available.
Interaction
Bicalutamide enhances the effect of indirect anticoagulants. Incompatible with astemizole, terfenadine, cisapride.
Increases the risk of adverse effects while taking Cyclosporine and medicines (Cimetidine, Ketoconazole), inhibiting the oxidation processes in microsomes.
Terms of sale
The prescription is not required to buy Bicalutamide online.
Storage conditions
In a dry place at a temperature not exceeding 25°C.
Shelf life - 3 years
Reviews of Bicalutamide
Reviews of Bicalutamide in most cases positive. Taking the drug in many patients causes persistent remission. However, many of them note the appearance of abdominal pain, jaundice, weakness, hemoglobin decrease.