Septolete Total tabs 3mg + 1mg #16

Septolete Total instruction for use

You can buy Septolete Total on this page

Composition:

1 tablet for resorption contains:
active substance: Benzidineamine hydrochloride 3,000 mg
Cetylpyridinium chloride monohydrate 1.050 mg, equivalent to cetylpyridinium chloride 1,000 mg
auxiliary substances: eucalyptus of the rosaceous leaf oil 1,200 mg, levomentol 5,000 mg, sucralose (E955) 3,500 mg, citric acid (E330) 15,000 mg, isomalt (type M) (E953) 2471.285 mg, brilliant blue dye (E133) 0.015 mg

Description:

Round tablets with beveled edges with a rough surface from light blue to blue. Allowed white coating, uneven staining, the presence of air bubbles in the caramel mass and a slight uneven edges.
Pharmacotherapeutic group:
Non-steroidal anti-inflammatory drug + antiseptic
ATX Code:
R02AA20

Pharmacological properties of Septolete Total

Pharmacodynamics

Benzidamine is an anti-inflammatory agent with anti-inflammatory, analgesic and local anesthetic effect. Cetylpyridinium chloride - an antiseptic from the group of quaternary ammonium compounds, has an antimicrobial, antifungal, virucidal action.

Pharmacokinetics

Suction
Of the two active substances - cetylpyridinium chloride and benzidamine - only benzydamine is absorbed through the mucous membranes. Therefore, cetylpyridinium chloride does not enter into a pharmacokinetic interaction with benzidamine at the systemic level. The absorption of benzidamine through the mucous membranes of the oral cavity and pharynx has been shown by identifying the active substance in the blood serum, the amount of which, nevertheless, was insufficient to provide systemic action. The absorption of benzidine is higher when using dosage forms that dissolve in the oral cavity compared with topical dosage forms (eg, oral spray).
Distribution
The volume of distribution of all dosage forms is the same.
Excretion
Excretion occurs mainly in the kidneys, to a greater extent, in the form of inactive metabolites. The half-life and overall clearance are similar for all dosage forms.

Indications for use

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (various etiology).

Contraindications

Hypersensitivity to active substances, or to any auxiliary components of the drug. Children under 12 years.

Carefully

Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including in the anamnesis).

Application Septolete Total in pregnancy and during breastfeeding

The use of the drug Septolete Total during pregnancy and during breastfeeding is possible only after consultation with the attending physician, if the intended benefit to the mother exceeds the potential risk to the fetus and the baby.

Dosing and Administration

Tablets should be slowly dissolved in the mouth every 3-6 hours.
Adults, elderly patients and children over 12 years of age
The recommended dose is 3-4 tablets per day.
Do not exceed the indicated dose. To achieve the optimum effect, do not apply the drug Septolete Total immediately before or after brushing your teeth.
The drug Septolete Total should not be used concurrently with other drugs from the group of antiseptics. The drug Septolete Total should not be used for more than 7 days.

Side effects of Septolete Total

Classification of the incidence of side effects recommended by the World
Health Organization (WHO):
very often> 1/10
often from> 1/100 to <1/10
infrequently from> 1/1000 to <1/100
rarely from> 1/10000 to <1/1000
very rarely <1/10000
the frequency of the unknown can not be estimated from the available data.
Immune system disorders:
rarely: hypersensitivity reactions;
frequency unknown: anaphylactic reactions.
Impaired nervous system:
frequency unknown: numbness of the oral mucosa.
Disturbances from the respiratory system, chest and mediastinal organs:
rarely: bronchospasm.
Disorders from the gastrointestinal tract
very rarely: irritation of the oral mucosa, burning sensation in the cavity
Disturbances from the skin and subcutaneous tissues:
rarely: urticaria, photosensitivity;
frequency unknown: angioedema, skin itching.

Overdose

Symptoms: toxic manifestations of benzodamine overdose include: agitation, convulsions, increased sweating, ataxia, chills and vomiting. Signs and symptoms of intoxication when ingesting significant amounts of cetylpyridinium chloride: nausea, vomiting, edema, cyanosis, asphyxia followed by paralysis of the respiratory muscles, central nervous system depression, hypotension and coma. The lethal dose for a person is about 1-3 g.
Treatment: in view of the absence of a specific antidote, the treatment of acute intoxication with benzydamine is symptomatic. Treatment of an overdose of cetylpyridinium chloride is also symptomatic. In case of overdose, see a doctor.

Interaction with other drugs

Not studied. Avoid simultaneous application with other drugs from the group of antiseptics.

special instructions

The drug Septolete Total should not be used for more than 7 days. If there are no visible signs of improvement, you should consult your doctor.
With the use of the drug Septolete total, hypersensitivity reactions may develop. In this case, it is recommended that you stop treatment and consult with your doctor to prescribe appropriate therapy. If there is a ulcerative lesion of the mucous membrane of the oropharynx, the patient should consult a doctor if the symptoms persist for more than three days.
The use of the drug Septolete Total is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
The drug Septolete Total should not be used simultaneously with anionic compounds (for example, present in toothpaste).
Therefore, the use of the drug is not recommended immediately before or after brushing the teeth.
Simultaneous reception with milk can reduce the antimicrobial effect of cetylpyridinium chloride, so the drug Septolete Total should not be used simultaneously with milk.
Influence on the ability to perform potentially hazardous activities requiring special attention and quick reactions (for example, vehicle management, work with moving mechanisms)
The drug Septolete Total does not affect the ability to drive vehicles and work with mechanisms.

Form of issue

Tablets for resorption, 3 mg + 1 mg.
For 8 tablets in a blister of the combined material PVC / polyethylene / PVDH-aluminum flags.
For 1, 2, 3 or 4 blisters are placed in a pack of cardboard along with instructions for use.

Storage conditions

At a temperature of no higher than 25 ° C, in the original packaging.
Keep out of the reach of children.
Shelf life - 2 years.
Do not use the drug after the expiration date.

Leave conditions

You can buy Septolete Total without a prescription.