Cophicyl-Plus tabs #10

Cophicyl-Plus instruction for use

You can buy Cophicyl-Plus tablets on this page

Composition

In 1 tablet of the preparation Cophicyl-Plus contains 100 mg of paracetamol, 300 mg of acetylsalicylic acid, 50 mg of caffeine.
Excipients: silicone emulsion, stearic acid, potato starch, talc, vaseline oil, povidone.

Form of issue

    10 tablets in a box; 1, 3, 2, 4 or 5 packages in a cardboard bundle.
    6 tablets in a non-jammed package; 1, 3, 2, 4 or 5 packages in a cardboard bundle.
    10 tablets in a cellulose-free package; 1, 3, 2, 4 or 5 packages in a cardboard bundle.

pharmachologic effect

Anesthetic, psycho-stimulating, anti-inflammatory, antipyretic action.

Pharmacodynamics and pharmacokinetics

Polycomponent.

Acetylsalicylic acid has antipyretic and anti-inflammatory effect, reduces pain, and also moderately suppresses platelet aggregation and thrombogenesis processes, improves perfusion in the focus of inflammation.
Paracetamol has an analgesic, antipyretic and weak anti-inflammatory effect, which is due to its effect on the thermoregulatory center and weakly expressed ability to suppress the biosynthesis of prostaglandins.
Caffeine increases the excitability of the spinal cord, vasomotor and respiratory centers, dilates the kidneys, vessels of muscles, brain, heart, reduces platelet aggregation; reduces fatigue, drowsiness, increases efficiency.
In this combination, almost no stimulating effect on the brain, but it helps regulate the tone of the vessels of the brain and accelerate the perfusion.

Indications for use Cophicyl-plus

What helps Cophicyl-plus (indications for use):
    pain syndrome (diverse genesis - toothache, arthralgia, migraine, myalgia, algodismenorea, headache, neuralgia);
    fever for respiratory acute diseases and influenza.

Contraindications

    Lesions of the digestive tract are erosive and ulcerative.
    "Aspirin" asthma.
    Hypersensitivity.
    Bleeding from the digestive system.
    Hemophilia.
    Hypoprothrombinemia.
    Avitaminosis K.
    Pregnancy or lactation.
    Severe ischemic heart disease.
    Renal failure.
    Lack of glucose-6-phosphate dehydrogenase.
    Severe arterial hypertension.
    Glaucoma.
    Sleep disturbances.
    Portal hypertension.
    Surgical interventions with presumed bleeding.
    Increased excitability.
    Hemorrhagic diathesis.
    Age is up to 15 years.
It is recommended with caution to take Cophicyl-Plus with gout or liver disease.

Side effects

Nausea, gastralgia, hepatotoxicity, vomiting, erosive and ulcerative digestive organs, tachycardia, allergic reactions, nephrotoxicity, increased blood pressure, bronchospasm.
With prolonged use, visual impairment, dizziness, tinnitus, weakening of platelet aggregation, hypocoagulation, deafness, headache, Reye syndrome, hemorrhagic syndrome, kidney damage are not excluded.

Instructions for use Cophicyl-Plus (Method and dosage)

Instruction for use Cophicyl-Plus prescribes to take the drug orally, during or after a meal, 1 tablet at intervals of four hours, with a painful syndrome take 1-2 tablets; the usual daily dose is 3-4 tablets, the largest daily dose is 8 tablets. The duration of therapy should not exceed 7-10 days.
The drug should not be taken for more than five days as an anesthetic and for more than three days as an antipyretic. Other dosages and patterns of use are determined by the physician.

Overdose

Signs of an overdose: nausea, ringing in the ears, gastralgia, vomiting, dizziness, blocking, collapse, drowsiness, bronchospasm, convulsions, shortness of breath, anuria, respiratory acidosis, bleeding.
Treatment of overdose: monitoring the pH-balance and balance of electrolytes, depending on the level of metabolism recommended the use of sodium citrate, sodium lactate or sodium bicarbonate.

Interaction

Joint use with other anti-inflammatory non-steroid drugs, methotrexate increases the likelihood of unwanted effects.
Reduces the effectiveness of spironolactone, Furosemide, antihypertensive and anti-arthritis agents that promote the evacuation of uric acid.
Metoclopramide enhances the absorption of paracetamol.
Salicylamide, barbiturates, rifampicin, antiepileptic drugs and other inducers of microsomal oxidation enhance the synthesis of toxic paracetamol derivatives that affect liver function.
Simultaneous use of paracetamol and ethanol increases the risk of hepatotoxic effects.
Under the action of Paracetamol, the half-life of Chloramphenicol is five times longer.
Caffeine enhances the absorption of ergotamine.

Terms of sale

You don't need a prescription to buy Cophicyl-Plus.

Storage conditions

Store at room temperature. Keep away from children.
Shelf life - 2 years.

special instructions

When the drug is used for a long time, it is necessary to monitor blood levels and liver status.
Children are prohibited from prescribing funds that include acetylsalicylic acid, since in case of infection they can increase the risk of Reye's syndrome (encephalopathy, vomiting, hepatomegaly).
Acetylsalicylic acid in small doses weakens the evacuation of uric acid.
Acetylsalicylic acid has a teratogenic effect.

Children

The drug is not used in children younger than 15 years.

In pregnancy and lactation

Do not use the drug in these periods.

Reviews

Headache is one of the most common disorders, from which the Cophicyl-Plus tablets, according to the testimonials, are good help. Side effects occur infrequently. There is evidence that Cophicyl-Plus is increasing the pressure.