Diclovitum gel 1% 20gr

User manual for Diclovitum

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Composition

The active component of the drug in the form of Suppositories and gel is diclofenac sodium.
Suppositories Diclovitum have the following additional components: vitepsol, suppository.
Additional components of the gel: rectified ethyl alcohol, lactic acid 40%, carbopol, purified water, isopropanol, sodium disulphite, trolamine.
Capsules contain such active ingredients as diclofenac sodium, pyridoxine hydrochloride, thiamine hydrochloride, cyanocobalamin. Auxiliary elements - povidone, triethyl citrate, iron oxide red, titanium dioxide, methacrylic acid, talc, iron oxide yellow, gelatin.

Form of issue

In pharmacies, Diclovitum gel is sold, as well as capsules and suppositories.

pharmachologic effect

The drug belongs to the NSAID.

Pharmacodynamics and pharmacokinetics

This drug has anti-inflammatory, antipyretic, analgesic and antiaggregatory properties. It is based on inhibition of the activity of cyclooxygenase I and II. This causes a violation of the metabolism of arachidonic acid. In turn, the synthesis of prostaglandins decreases in the site of inflammation. Pain in the joints decreases in a state of rest and motion. The morning stiffness, swelling of the joints disappears or becomes dulled. The drug also helps in increasing the amount of movement in the joints.
The medicine reduces the pain syndrome in traumatic and postoperative pains, as well as the severity of inflammatory reactions. Reduces bleeding and painful sensations in primary algodismenorrhea.
When using Suppositories, the maximum concentration is noticeable in half an hour.

Indications for use

The medicine is used when:
    lumbulgia;
    inflammatory and degenerative diseases of the musculoskeletal system;
    humeroscapular periarthritis;
    lumbago;
    bursitis;
    neuralgia;
    inflammations, trimeses, pain, swelling due to dental, gynecological, orthopedic and other interventions;
    myalgia;
    synovitis;
    tenosynovitis;
    post-traumatic pain syndromes;
    migraine attacks;
    postoperative pain;
    colic.
The use of Suppositories Diclovitum in gynecology is indicated for primary dysmenorrhea, perimeter, adnexitis. In addition, it can be an additional agent as a component of the combined treatment of infectious and inflammatory diseases of the ENT organs, which are accompanied by a pronounced pain.

Contraindications

It can not be used in case of hypersensitivity to its components and other NSAIDs, hematopoiesis of unknown origin, aspirin asthma, pregnancy, exacerbation of gastric and duodenal ulcer, exacerbation of erosive and ulcerative gastrointestinal lesions, aspirin triad, children under 6 years of age . With caution, it is prescribed in the case of induced acute hepatic porphyria, as well as problems with the functioning of the liver and kidneys.

Side effects

Taking the drug may cause the following side effects:
    digestive system - ulcerative colitis in the acute stage, gastralgia, vomiting, stomach pain, constipation, anorexia, bleeding in the gastrointestinal tract, fulminant hepatitis, nonspecific colitis with bleeding, Crohn's disease in the acute stage, nausea, diarrhea, indigestion, flatulence , increased activity of hepatic transaminases, pancreatitis, hepatitis;
    urinary system - hematuria, acute renal failure, nephrotic syndrome, proteinuria, papillary necrosis, interstitial nephritis;
    skin - skin rash, eczema, exfoliative dermatitis, photosensitivity, bullous eruptions, polymorphic erythema, alopecia, purpura;
    nervous system - headache, severe fatigue, paresthesia, loss of orientation, diplopia, tinnitus, irritability, depression, nightmares, psychotic reactions, dizziness, confusion, memory loss, decreased visual acuity and hearing, insomnia, convulsions, anxiety, tremor , a violation of taste sensations;
    hemopoietic system - thrombocytopenia, agranulocytosis, aplastic and hemolytic anemia, leukopenia;
    allergies - allergic purpura, bronchospasm, urticaria, Stevens-Johnson syndrome, Lyell's syndrome, anaphylactic conditions;
    other - swelling, pain in the chest, high blood pressure, impotence, a feeling of heartbeat;
    local reactions - mucous discharge with an admixture of blood, irritation of the mucosa of the colon, painful sensations during defecation.
Adverse events depend on individual characteristics, duration of the course and dosages.

Instructions for use Diclovitum (Method and dosage)

The medicine can be used for adults and children from 15 years. Suppositories are injected rectally into the rectum after cleansing enemas or bowel movements. When using them, it is necessary to lie for 20-30 minutes. If Suppositories are used Diclovitum, the instructions for use inform you that they should be put twice a day. Maximum of 3 suppositories per day.
Instructions for use Diclovitum indicates that the duration of therapy is determined on an individual basis, depending on the nature of the disease and the personal tolerability of the drug.
Ointment is intended for external use. A strip of 1-2 cm is applied a thin layer over the site of inflammation 2-3 times a day. It must be rubbed with gentle movements until it is completely absorbed. Therapy does not last longer than 2 weeks. Prolong the course is possible only after consulting a specialist. After using the gel, you need to wash your hands.
Capsules should be taken during meals, while always drinking plenty of liquid and not chewing. Typically, the dosage is 1 capsule from 1 to 3 times every day. For adults, appoint 3 appointments at the beginning of the course. Maintenance dosage - 1 capsule 1-2 times / day.
Children from 6 years are given a maximum of 2-3 mg of this drug per 1 kg of weight.
How many pills are taken depends on the doctor's appointment.

Overdose

Overdose of suppositories is unlikely. When the drug is used in high doses, headache, dizziness, hyperventilation, side reactions from the gastrointestinal tract, and confusion are possible. Children may experience pain in the abdomen, myoclonic cramps, nausea, vomiting, liver and kidney problems. In case of accidental use of the drug, it is recommended to rinse the stomach and take activated charcoal. Then symptomatic therapy is carried out.

Interaction

Diclovitum increases the plasma content of digoxin, lithium and phenytoin. It also inhibits the action of diuretics and antihypertensive drugs. When combined with potassium-sparing diuretics, hyperkalemia may even develop.
Interaction with other NSAIDs or glucocorticoids increases the likelihood of occurrence of adverse reactions from the gastrointestinal tract. The combination with acetylsalicylic acid leads to a decrease in the content of active substance Diclovitum in the serum.
With the simultaneous administration of Cyclosporin, its toxic effect on the kidneys increases. And antidiabetic drugs in combination with Diclovitum can cause hypo- or hyperglycemia. Therefore, it is necessary to constantly monitor the sugar content in the blood.
The combination of Methotrexate with Diclovitum (during the day before or after taking) can cause an increase in the level of Methotrexate and an increase in its toxic effect. When you use anticoagulants, you must always monitor the coagulability of the blood.

Terms of sale

You don't need a prescription to buy Diclovitum.

Storage conditions

Keep the drug at a temperature of up to 25 ° C.
Shelf life of the Suppositories - 2 years, gel and capsules - 3 years.

Reviews

As a rule, Diclovitum receives positive reviews. Those who used this drug in various forms, note its rapid effect. Patients are pleased that the drug has several actions at the same time: relieves swelling, removes inflammation, dulls pain, etc. However, reviews of Suppositories Diclovitum in gynecology sometimes report a personal intolerance to the drug, but the symptoms of adverse reactions quickly pass with a decrease in dosage. Among the minuses of the gel, only note that it has to be rubbed for a long time so that the product is completely absorbed.