Katadolon caps 100mg #30

Katadolon instruction

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Two main analogues of Katadolon - Neurodolone and Nolodatac

Composition

One capsule contains 100 mg of flupirtine maleate + excipients (gelatin, water, E172, sodium lauryl sulfate, titanium dioxide, silicon dioxide, magnesium stearate, copovidone, calcium hydrogen phosphate dihydrate).
In one pill Fortad Katadolon and Katadolon Retard: maleate flupirtine 400 mg + excipients.

Form of issue

Description of the Katadolon: ​​capsules in a shell of gelatin, monophonic red, the contents are a powder of yellow or greenish-yellow shades. Cardboard packs of 30,10 and 50 tablets.
Katadolon Forte - yellow tablets, biconvex, may contain various impregnations, oval, on one side of the risk. Blisters for 7, 10 and 14 pieces.
Katadolon Retard - capsules in a shell of gelatin, red. Packages of 30, 10 and 50 pieces.

pharmachologic effect

An analgesic with an antispastic effect.

Pharmacodynamics and pharmacokinetics

The drug is a non-opioid analgesic. Has a central effect. Not addictive. Affects the regulatory G-protein, changing the potential difference in the calcium channels, thereby stabilizing the potential of neuronal membranes.
In doses not exceeding the maximum permissible, the substance does not affect M- and H-cholinergic receptors, dopamine, opioid, serotonin and alpha1 and alpha2-adrenergic receptors.
Anesthesia occurs due to the opening of potassium channels in nerve cells. The drug affects NMDA receptors and thereby, stops the flow of calcium ions through the semi-impermeable membrane wall. Flupirtine does not give a nervous impulse to respond to received nociceptive stimuli, thus anesthetizing. The medicine gets newly arisen painful sensations, not allowing them to "inflate" and grow into chronic ones. The drug effectively reduces the already formulated chronic pain.
Miorelaxation occurs by blocking motto- and intermediate neurons.
The drug has the property of protecting neurons from toxic effects. By activating the calcium channels, the agent thereby reduces the amount of damaging calcium ions in the cell.
When entering the GIT, 90% of the drug is fully absorbed. 75% of the dose taken undergoes a metabolic process in the liver.
Half-life from the body is 7 hours. At the Katadolon Forte and Retard - 15 hours (due to the slow stepwise release of the active substance). Up to 70% is excreted by the kidneys, the rest - through the intestines (feces and bile). In elderly patients and people with disabilities in the kidney and liver, the withdrawal period from the body increases.

Indications for use of the Katadolon

Indications for the use of the drug are pain of various genesis, caused by spasms of smooth muscles.
From what tablets? Postoperative and headaches, in the neck and back, with malignant tumors and neoplasms, etc.

Contraindications

The drug is not recommended for hypoalbuminemia, liver and kidney diseases, allergies to the active substance or auxiliary components, ringing in the ears, the treatment of children and the elderly and alcoholics.

Side effects

Often there is fatigue and dizziness, general weakness, less often - nausea, flatulence, abdominal pain and digestive disorders, tremor, headache, anxiety.
Rarely and very rarely patients develop allergic reactions, visual impairment, drug-induced hepatitis. Adverse reactions may disappear during the course of the drug.

Instructions for the use of Katadolon (Method and dosage)

Orally. Regardless of food intake. Duration of treatment and dosage is prescribed by the doctor, depending on the disease and its course. The maximum amount of flupirtine per day is 600 mg.
Adults: 3-4 tablets per day, at regular intervals. With very severe pain, you can increase the single dose to 200 mg, but not exceed the daily maximum. For patients older than 65, with kidney disease or hypoalbumism, the daily dose of the drug is 300 mg, with liver diseases of 200 mg.

Instructions for the Fortad Katadolon and the Katadolon Retard

The drug is prescribed one tablet (0.4 g) per day until the pain syndrome disappears.

Overdose

There is confusion, tachycardia, nausea, dryness of the mucous membranes. In case of an overdose - gastric lavage and treatment, according to the manifested symptoms.

Interaction

With simultaneous administration with warfarin and diazepam, due to the fact that these drugs bind to proteins, flupirtine can be squashed from the cell and the action of the drug can increase.
Miorelaxants, sedatives and ethanol increase their effect under the influence of the drug.
It is not recommended to combine with carbamazepine, paracetamol and flupirtine. It is worth monitoring the prothrombin index while taking with coumarin.

Terms of sale

To buy Katadolon the prescription is not requered.

Storage conditions

In a dark cool place (from 15 to 25 degrees). Do not allow children to fall into the hands.

Shelf life

Katadolon - 5 years.
Katadolon Forte and Retard - up to 2 years.

special instructions

Care should be taken when taking the drug and controlling the mechanisms, since the drug can reduce the reaction speed and visual acuity. Flupirtine can stain urine in a greenish color.

In pregnancy and lactation

Not applicable.

Reviews of the Katadolon

Katadolon Retard removes the pain syndrome quickly and permanently. Despite the frequent manifestations of side effects, some addicts use the drug for pain relief during abstinence.
Many write good reviews on the Catalonia Fort 400 mg. The drug effectively reduces pain, but often shows dizziness and general weakness.
Reviews of doctors: The medicine is good and quickly anesthetizes, it is used in surgical practice. Does not cause addiction. However, it is quite a strong remedy, so it is not worth taking a drug without a doctor's appointment.