Tempalgin #20

Instruction for Tempalgin

Reed more and buy Tempalgin on this page

Tempalgin tablets represent a clinical and pharmacological group of medicines combined non-steroidal anti-inflammatory drugs. They are used to reduce elevated body temperature with fever, as well as to reduce the severity of pain in the inflammatory reaction of any localization in the body.

Dosage form, composition

Tempalgin tablets are green, round in shape, biconvex shiny surface. They are covered with an enteric membrane. The composition of the drug includes several basic active ingredients, their content in one tablet is:
    Metamizole - 500 mg.
    Tempidon (triacetonamine 4-toluenesulfonate) 20 mg.
Also included in the tablet are excipients, which include titanium dioxide, microcrystalline cellulose, crospovidone, castor oil, magnesium stearate, wheat starch, eudrazhit L acetone, glycerol, polyethylene glycol, talc, dibutyl phthalate, green dye. Tempalgin tablets are packaged in a blister for 10 pieces. Cardboard pack contains 2 or 10 blisters with tablets, as well as instructions for using the drug.

Therapeutic effects, pharmacokinetics

tempalgin tablets are a combined preparation with antipyretic (antipyretic) and analgesic (analgesic) action, which is realized due to the basic active ingredients in the composition of the drug. Metamizole refers to non-opiate analgesics, it reduces the severity of moderate pain. Tempdione exerts an undesirable soothing (sedative) effect, and also has anti-inflammatory activity.
After taking Tempalgin tablets, the active ingredients are absorbed into the blood from the intestinal lumen. They are almost evenly distributed in tissues, metabolized in the liver with the formation of inactive decay products, which are excreted mainly in the urine.

Indications for use

Reception of tablets Tempalgin is indicated in pathological conditions in which it is necessary to achieve the therapeutic effects of these medicines:
    Slightly expressed pain sensations localized in the internal organs (pain of visceral origin), including hepatic or renal colic (the drug is used in combination with antispasmodic drugs).
    Pain of moderate degree of severity of different origin and localization - dental, headache (including migraine attacks of moderate severity), pain, neuralgia (aseptic inflammation of the peripheral nerves accompanied by pain), arthralgia (joint pain), algodismenorea (painful menstruation in women), osteochondrosis with the development of radicular pain.
    An increase in body temperature with intoxication of an organism of infectious or non-infectious origin.
Also, the drug is used for complex with other drugs to reduce the severity of pain during the performance of invasive diagnostic or surgical interventions. The therapeutic effect is more achieved in patients with increased nervous excitability.

Contraindications to use

There are a number of contraindications for the use of Tempalgin tablets, which include some pathological or physiological conditions of the patient's body:
    "Aspirin" asthma is a complex of pathological allergic reactions that develop due to the introduction of non-steroidal anti-inflammatory medicines into the patient's body of medicines. The reaction is often accompanied by an attack of constriction of the bronchi (bronchospasm) and clinically resembles bronchial asthma.
    Pronounced decrease in arterial pressure (arterial hypotension).
    A marked decrease in the functional activity of the kidneys or liver.
    Chronic heart failure, accompanied by a decrease in the contractility of the myocardium.
    Pathological oppression of hemopoiesis in the red bone marrow, accompanied by a decrease in the number of leukocytes (leukopenia), granulocytes (agranulocytosis), neutrophils (neutropenia) in the blood.
    Deficiency of the enzyme glucose-6-frasfatdegidrogenazy.
    Pregnancy at any time of the course, as well as the period of breastfeeding (lactation).
    The patient's age is less than 14 years.
    Individual hypersensitivity to any of the components of this medication.
With caution, the drug is used in patients with concomitant renal and hepatic pathology, accompanied by a moderate decrease in their functional activity, bronchial asthma, predisposition to lowering the level of systemic arterial pressure, chronic alcoholism. Before using this medication, it is important to exclude contraindications.

Usage rules, dosage

Tempalgin tablets are intended for oral administration. They are taken after meals, they are not chewed and washed down with enough water. The average therapeutic dosage for adults and adolescents over 14 years is 1 tablet 1-3 times a day, depending on the severity of the pain syndrome and the effectiveness of the drug. The maximum single dose should not exceed 2 tablets, daily dose - 6 tablets. The duration of taking Tempalgin tablets should not exceed 5 days. The possibility of increasing the dosage or the duration of the course of treatment with this medication is determined only by the doctor in accordance with the indications.

Side effects

After the beginning of taking Tempalgin tablets, there may appear negative reactions from various organs and systems that are of nonphysiological origin, they include:
    The digestive system - dry mouth, burning sensation behind the sternum along the esophagus, a violation of the liver's functional activity and hepatobiliary tract structures, accompanied by increased activity of hepatic transaminase enzymes in the blood (evidence of hepatocyte liver damage), jaundice and increased bilirubin level.
    Nervous system - dizziness, intermittent headache, in quite rare cases, the appearance of auditory and visual hallucinations.
    Cardiovascular system - decrease or increase in the level of systemic arterial pressure, palpitations (tachycardia), worsening of venous outflow of blood, accompanied by cyanotic staining of the skin or mucous membranes (cyanosis) of different localization.
    The urinary system is the coloring of the urine in red, a decrease in the functional activity of the kidneys, which usually develops when using high doses of the given drug.
    Blood and red bone marrow - a decrease in the number of platelets (thrombocytopenia), neutrophils (neutropenia), leukocytes (leukopenia), granulocytes (agranulocytosis) in the blood.
    Allergic reactions - a rash on the skin, its itching, characteristic changes, in appearance resembling a nettle burn (urticaria), pronounced swelling of soft tissues with predominant localization in the face and external genital organs (angioedema Quincke), necrotic lesion of the skin with the death of its cells (Lyell's syndrome, Stevens-Johnson syndrome), an attack of bronchial constriction with impaired respiratory function and severe shortness of breath (bronchospasm), and a systemic reaction with a critical drop in blood pressure and the development of a multi-organ insufficiency (anaphylactic shock).
If there are signs of negative pathological reactions after the beginning of taking Tempalgin tablets, the doctor in charge of the need to cancel the drug or adjust the dosage individually, which depends on their nature, as well as their severity.

Special Recommendations

Before starting taking Tempalgin tablets, it is important to carefully read the instructions to the drug and pay attention to several recommendations regarding its correct use, which include:
During the course of treatment with this drug, alcohol consumption is excluded, since this can lead to its excessive depressing effect on the brain.
    Since, with the reception of tempalgin tablets, a significant decrease in granulocytes in the blood (agranulocytosis) accompanied by fever of unknown origin, inflammation of the mucous membrane of the oral cavity, sore throat, difficult swallowing, then when such symptoms appear, the drug should be stopped immediately and consult a medical professional .
    The course of therapy with this drug, exceeding 7 days, requires periodic laboratory monitoring of the functional state of the liver, kidneys, and also the picture of peripheral blood.
    Until the cause of acute pain in the abdomen is ascertained, the drug can not be taken, since the analgesic effect may make diagnosis difficult.
    The active components of this medication can interact with a significant number of drugs from other pharmacological groups, so their doctor must be warned about their possible use.
    Against the background of the use of the drug, it is recommended to refrain from engaging in potentially dangerous activities, which is related to its effect on the nervous system (sedation).
In the pharmacy chain, Tempalgin tablets are dispensed without a prescription. If you have any questions regarding the correct use of this medication, it is advisable to consult a medical professional.

Excess dosage

In case of exceeding the recommended therapeutic dosage of Tempalgin tablets, abdominal pain, nausea accompanied by vomiting, increased heart rate, lowering of blood pressure, tinnitus, shortness of breath, drowsiness, impaired consciousness, stiffened skeletal muscle cramps. In this case, the stomach, intestines are washed, intestinal sorbents are prescribed (activated charcoal), forced diuresis is performed for blood purification, hemodialysis (a procedure for blood purification), and symptomatic therapy. All therapeutic measures are performed in the conditions of a medical hospital.

Tempalgin analogues

Similar in therapeutic effect for Tempalgin tablets is Analgin.

Storage Rules

Shelf life of the tablets is 4 years. They are important to store correctly - in the original factory packaging, protected from light and moisture place at an air temperature of not more than +25 ° C. Keep out of the reach of children.