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Berotec H aerosol 100mcg/dose 10ml 200doses

  • $22.25
  • 3 or more $21.99
  • Availability:In Stock

Instruction for Berotec HYou can buy aerosol Berotec H hereComposition    1 dose of aerosol contains:    Active substance: fenoterola hydrobromide - 100 mcg and 200 mcg.    Excipients: ..

Instruction for Berotec H

You can buy aerosol Berotec H here


    1 dose of aerosol contains:
    Active substance: fenoterola hydrobromide - 100 mcg and 200 mcg.
    Excipients: citric acid anhydrous 0.001 mg, absolute ethanol 15.597 mg, purified water 1.04 mg, 1,1,1,2-tetrafluoroethane (HFA 134a, propellant) 35.252 mg.
200 doses.

pharmachologic effect

Fenoterol hydrobromide is a selective stimulant of beta2-adrenergic receptors.
Activates adenylate cyclase through the stimulatory GS protein, followed by an increase in cAMP production, which in turn activates protein kinase A. The latter phosphorylates target proteins in smooth muscle cells. This in turn leads to phosphorylation of myosin light chain kinase, inhibition of phosphoinosin hydrolysis, and the discovery of calcium-activated, fast potassium channels.
Thus, fenoterol relaxes the smooth musculature of the bronchi and vessels, and also prevents the development of bronchospasm caused by the effects of bronchoconstrictor factors such as histamine, methacholine, cold air and allergens (immediate reaction). After taking the drug, the release of inflammatory mediators from the mast cells is inhibited. In addition, after taking fenoterol in high doses, there is an increase in mucociliary transport.
Higher concentrations of the drug in the blood plasma, achieved after oral or more often, after intravenous administration, inhibit uterine contractility. When taking high doses of the drug, there are effects at the level of metabolism: lipolysis, glycogenolysis, hyperglycemia and hypokalemia (the latter is due to increased absorption of K + skeletal muscle).
Beta-adrenergic effects of the drug at the level of the heart muscle, such as increased heart rate and increased myocardial contractility, are explained by the action of fenoterol on the vessels, stimulation of β2-adrenergic receptors of the heart, and when taking the drug in doses exceeding the therapeutic ones, stimulation of β1-adrenergic receptors. The often observed effect of β-adrenoreceptor agonists is tremor. Unlike the effect on the smooth muscles of the bronchi, the systemic effects of β-adrenergic agonists are associated with the development of tolerance.
Fenoterol prevents and quickly reduces bronchospasm of various genesis (physical activity, cold air, early response to the allergen effect).
The onset of action after inhalation - after 5 minutes, the duration of action - 3-5 hours.

Berotec H, indications for use

Attacks of bronchial asthma or other conditions with reversible airway obstruction (including chronic bronchitis, COPD); prevention of bronchial asthma attacks physical effort.

Contraindications for Berotec H

    Hypertrophic obstructive cardiomyopathy.
    Children under 4 years.
    Hypersensitivity to fenoterol and other components of the drug.
With caution, the drug should be prescribed for hyperthyroidism, arterial hypotension, arterial hypertension, intestinal atony, hypokalemia, diabetes mellitus, recent myocardial infarction (within the last 3 months), heart and vascular diseases such as chronic heart failure, ischemic heart disease, coronary artery disease, heart disease (including aortic stenosis), severe cerebral and peripheral arterial lesions, pheochromocytoma. Because information about the use of the drug in children under the age of 6 is limited, treatment is carried out with caution, only under the supervision of a doctor.

Dosing and Administration

Adults and teenagers over 12 years of age

Attacks of bronchial asthma and other conditions, accompanied by reversible airway obstruction
In most cases, 1 inhalation dose is sufficient to stop bronchospasm; if no breathing has occurred within 5 minutes, you can repeat the inhalation.
If the effect is absent after 2 inhalations, and additional inhalations are required, the doctor should be consulted without delay.
Prevention of asthma physical effort
1-2 inhalation doses to exercise, up to 8 inhalations / day.

Children from 6 to 12 years old

Attacks of bronchial asthma and other conditions, accompanied by reversible airway obstruction
In most cases, 1 inhalation dose is sufficient to stop bronchospasm; if no breathing has occurred within 5 minutes, you can repeat the inhalation.
If the effect is absent after 2 inhalations, and additional inhalations are required, you should immediately seek medical help.
Prevention of asthma physical effort
1-2 inhalation doses to exercise, up to 8 inhalations / day.

Children from 4 to 6 years

Due to limited experience in children younger than 6 years of age, the drug should be used only as directed by a doctor and under the supervision of adults.
Attacks of bronchial asthma and other conditions, accompanied by reversible airway obstruction
To stop bronchospasm, 1 inhalation dose is sufficient. If there is no effect, you should seek medical help without delay.
Prevention of asthma physical effort
1 inhalation dose to exercise, up to 4 inhalations / day.

Terms of use

To achieve the maximum effect, it is necessary to correctly use the metered aerosol.
Before using the metered aerosol for the first time, press the bottom of the canister twice.
Each time using a metered aerosol, the following rules must be observed.
    Remove the protective cap.
    Make a slow, deep exhalation.
     Holding the balloon, tightly grasp the tip of the lips. In this case, the arrow and the bottom of the can should be directed upwards.
     While drawing the deepest breath, simultaneously quickly press the bottom of the can before releasing 1 inhalation dose. Hold the breath for a few seconds, then take the mouthpiece out of the mouth and exhale slowly. If repeated inhalation is required, repeat the same procedure (points 2-4).
     Put the protective cap on.
    If the aerosol can is not used for more than 3 days, it is necessary to press the bottom of the canister once before use.
The cylinder is designed for 200 inhalations. Then the cylinder should be replaced. Despite the fact that some contents may remain in the container, the amount of drug released by inhalation decreases.
The inhaler should be washed at least once a week.
It is important to keep the mouthpiece of the inhaler clean so that the medicine does not accumulate and does not block the spraying.
For cleaning, first remove the dustproof cap and remove the container from the inhaler. Rinse the inhaler with warm water to remove accumulated medication and / or visible dust.
After cleaning, shake the inhaler and allow it to air dry without the use of heating devices. When the mouthpiece has dried, return the container and dust cap to their place.
The plastic mouthpiece is specially designed for the metered aerosol Berotec H and serves for accurate dosing of the drug. The mouthpiece should not be used with other metered aerosols. It is also not possible to use Berotec® H metered aerosol with other adapters.

Side effects of Berotec H

From the immune system: hypersensitivity.
From the side of metabolism: hypokalemia.
From the nervous system: agitation, nervousness, tremor, headache, dizziness.
From the cardiovascular system: myocardial ischemia, arrhythmia, tachycardia, palpitation, increased systolic blood pressure, reduced diastolic blood pressure.
On the part of the respiratory system: paradoxical bronchospasm, irritation of the larynx and pharynx.
From the digestive system: nausea, vomiting.
From the skin and subcutaneous tissues: hyperhidrosis, skin reactions, such as rash, itching, urticaria.
From the musculoskeletal system: muscle spasm, myalgia, muscle weakness.

special instructions

At the first use of the Berotec H metered aerosol, patients can note that the new aerosol has a slightly different taste compared to the previous aerosol containing freon. Patients should be warned about this when switching from one drug formula to another. Patients should be aware that both formulas of the drug are completely interchangeable, and a change in taste does not affect the effectiveness and safety of the new aerosol formula.
Other sympathomimetic bronchodilators can be administered simultaneously with Berotec H only under medical supervision.
Possible simultaneous use of fenoterol and anticholinergic bronchodilators.
In case of sudden development and rapid progression of dyspnea, it is necessary to consult a doctor without delay.

Prolonged use of the drug:

- treatment according to need (symptomatic) is preferable to regular use of the drug;
- Regular examination of patients is necessary to determine the need for additional or more intensive anti-inflammatory treatment (eg inhaled corticosteroids).
Regular use of increasing doses of preparations containing beta2-adrenomimetics, such as Berotec H, for arresting bronchial obstruction can cause uncontrolled worsening of the course of the disease.
In the case of increased bronchial obstruction, a simple increase in the dose of beta2-adrenomimetics, including Berotec H, ​​more than recommended for a long time, is not only not justified, but also dangerous. To prevent a life-threatening deterioration in the course of the disease, consideration should be given to reviewing the patient's treatment plan and adequate anti-inflammatory therapy with inhaled corticosteroids.
With the appointment of beta2-adrenomimetics possible development of severe hypokalemia. In this regard, special care is required for severe asthma, since in this case, hypokalemia can occur as a result of the simultaneous administration of beta2-adrenomimetics, xanthine derivatives, glucocorticoids and diuretics. In addition, hypoxia may increase the effect of hypokalemia on the heart rhythm. It is recommended to monitor the level of potassium in the blood plasma.
In patients with diabetes mellitus during treatment, regular monitoring of glucose in the plasma should be carried out.

Influence on the ability to drive and machine machinery

Not installed.

Drug Interactions

Beta-adrenergic, anticholinergics, xanthine derivatives (eg, theophylline), cromoglycic acid, glucocorticosteroids can enhance the effect of fenoterol. The simultaneous administration of other beta-adrenomimetics, anticholinergics, xanthine derivatives (eg, theophylline), glucocorticosteroids, diuretics entering the systemic circulation with Berotec H may exacerbate side effects.
Perhaps a significant reduction in the bronchodilating action of Berotec H with simultaneous administration of beta-blockers.
Hypokalemia associated with the use of beta-adrenomimetics can be enhanced by the simultaneous administration of xanthine derivatives, steroids and
Caution should be used to prescribe beta-adrenergic agents for patients receiving monoamine oxidase inhibitors, tricyclic antidepressants, since these drugs can enhance the action of fenoterol.
Inhalations of halogenated hydrocarbon anesthetics, for example halothane, fluorotan, trichlorethylene or enflurane, sensitize the myocardium to the action of fenoterol, which contributes to the development of arrhythmia.


Symptoms: tachycardia, increased heart rate, tremor, decreased / increased blood pressure, increased pulse pressure, anginal pain, arrhythmias and hyperemia of the face.
Treatment: the appointment of sedatives, tranquilizers, in severe cases, intensive symptomatic therapy is indicated. As specific antidotes, the appointment of beta-blockers (preferably selective beta-1 blockers) is recommended. However, it is necessary to consider the possibility of strengthening bronchial obstruction and carefully select the dose of these drugs for patients with bronchial asthma.

Storage conditions

Keep out of reach of children at a temperature of no higher than 25 ° C.
The cylinder is under pressure. The cylinder can not be opened and heated to a temperature above 50 ° C.
Shelf life - 3 years

Terms of sell

You don't need a prescription to buy Berotec H.

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