Acidin-Рepsin tablets 250 mg #50

Instruction for Acidin-Рepsin

Reed more and buy Acidin-Рepsin

Composition

The preparation contains active components: acid (betaine) and pepsin.
Additional constituents: povidone, sorbitol, silicon dioxide colloid, calcium stearate.

Form of issue

Issue Acidin-Pepsin in the form of powder, solution and tablets 250 and 500 mg of 50 pieces per pack. Also in some pharmacies you can buy a specially prepared ointment with pepsin 5-10%, on a lanolin or vaseline basis.

pharmachologic effect

This drug has a combined effect. Improves the digestion of food in the stomach.

Pharmacodynamics and pharmacokinetics

Pepsin - what is it?

According to the Pharmacopeia, pepsin is an enzyme that is part of the gastric juice that produces the mucous membrane of the stomach. It has also been established that this enzyme ensures the cleavage of virtually all proteins of plant and animal origin. In addition, trypsin and chymotrypsin, which are enzymes of the pancreas, participate in this process. However, it is this enzyme that breaks down proteins without showing them specificity, that is, it acts in an acidic environment.
Some diseases of the gastrointestinal tract cause a significant decrease or lack of production of hydrochloric acid, which leads to insufficient digestive activity of pepsin, and, accordingly, gastric juice. Therefore, patients are prescribed replacement therapy in the form of drugs based on it. For example, when taking the enzyme drug Acidin-Pepsin, one of its constituents - betaine hydrochloride is converted in the stomach to hydrochloric acid, activating the enzyme, which improves digestion.

Indications for use

The main indications for the administration of Acidin-Pepsin are various gastrointestinal diseases, which are characterized by a decreased secretory function of the stomach. Therefore, the drug is recommended for:
    hypoacid gastritis;
    anacid gastritis;
    Achilia - the lack of synthesis of hydrochloric acid and other digestive enzymes with atrophic gastritis, nutrition with a lack of proteins and vitamins, liver cirrhosis, malignant form of anemia, endocrine disorders;
    dyspepsia;
    period after removal of part of the stomach.
Preparations for external use are used in the treatment of keloid scars or necrotic, long-healing wounds and ulcers.

Contraindications for use

This enzyme preparation is not recommended for:
    hypersensitivity;
    hyperacidity of gastric juice, for example: erosive gastroduodenitis, gastric ulcer and 12-colon.

Side effects

When taking the drug may develop allergic reactions, nausea, heartburn, abdominal pain.

Acidin-Pepsin, instructions for use (Method and dosage)

As the instruction on Acidin-Pepsin informs, the preparation in tablets is intended for reception inside simultaneously or after meal. For this, the tablets must be dissolved in 50-100 ml of water. Adult patients are recommended a daily dosage of 2 tablets, taken 3-4 times. Children's dosage is a quarter or half of the pill to be taken 3-4 times a day.
The duration of the therapeutic course depends on the course of the disease and the effectiveness of treatment, which the specialist is able to determine.

Overdose

Usually this drug is well tolerated by patients, so in clinical practice, cases of overdose are not described. At the same time, development is possible: nausea, heartburn, gastralgia, vomiting, diarrhea and various allergic reactions.

Interaction

Simultaneous use of enzyme preparations and acid-binding agents, tannin and antacids reduces its effectiveness, as well as preparations, with salts of heavy metals, for example: salicylic-sulfur-zinc paste, Collargol and so on.

Terms of sale

This drug can be bought without a prescription.

Storage conditions

Store the enzyme preparation can be in a dry, cool, dark place, inaccessible to children.

Shelf life

1,5 years.

Alcohol

It is established that alcohol has a destructive effect on pepsin. Therefore, during treatment with this drug from drinking alcohol-containing beverages should refrain.