Antareit tabs 800mg + 40mg #24
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Antareit instruction for useYou can buy Antareit on this pageComposition1 tablet chewing dosage of 400/20 mg contains:Active substances: magdrate - 400 mg, simethicone (in terms of dimethylpolysiloxane) - 30.77 (20) mg.Excipients:..
Antareit instruction for use
You can buy Antareit on this page
1 tablet chewing dosage of 400/20 mg contains:
Active substances: magdrate - 400 mg, simethicone (in terms of dimethylpolysiloxane) - 30.77 (20) mg.
Excipients: ethyl cellulose -18.0 mg, macrogol-4000- 70.0 mg, sorbitol-256.59 mg, sucralose-2.16 mg, aspartame-2.50 mg, caramel flavoring-6.48 mg, silicon dioxide colloid - 4,5 mg, glyceryl dibehenate - 9.0 mg.
1 tablet chewing dose of 800/40 mg contains:
Active substances: magdrate - 800 mg, simethicone (in terms of dimethylpolysiloxane) - 61.54 (40) mg.
Excipients: ethylcellulose 36.00 mg, macrogol 4000 to 140.0 mg, sorbitol 513.18 mg, sucralose 4.32 mg, aspartame 5.0 mg, caramel flavor 12.96 mg, silicon dioxide colloid - 9.0 mg, glyceryl dibehenate - 18.0 mg.
Biconvex tablets white or almost white, octagonal in shape, with beveled edges, with an engraved apple and the letter "g" on one side. Presence of dark inclusions is allowed.
Antacid agent + carminative agent
ATX code: A02AF02.
Pharmacological properties of Antareit
Combined drug, the effect of which is due to the properties that make up its components. Has antacid, adsorbing, enveloping, carminative effect.
Magaldrate (aluminum magnesium hydroxide sulfate) neutralizes free hydrochloric acid in the stomach, without causing secondary hypersecretion of gastric juice. In connection with the increase in pH during its intake, the peptic activity of gastric juice decreases. It has an adsorbent and enveloping effect, due to which the effect of damaging factors on the gastric mucosa decreases, binds bile acids.
Simethicone changes the surface tension of gas bubbles formed in the contents of the stomach and mucus of the intestine, and causes their destruction. The gases released in this way can be absorbed by the cells of the walls of the intestine, or be excreted by peristalsis. Simethicone removes foam purely physically, does not enter into chemical reactions, is pharmacologically inert.
Absorption of aluminum and magnesium ions in the blood is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal insufficiency, the content of aluminum and magnesium in the blood can rise to toxic values as a result of disruption of their excretion.
Simethicone due to pharmacological and chemical inertness after ingestion is not absorbed into organs and tissues. After passing through the gastrointestinal tract (GASTROINTESTINAL TRACT) is excreted unchanged by the intestine.
Indications for use
Symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, belch "sour taste", pain in the stomach (appear irregularly), feeling of overflow or heaviness in the epigastric region, flatulence, dyspepsia (including, due to inaccuracy in the diet , medication, alcohol, coffee, nicotine abuse).
Contraindications for Antareit
Hypersensitivity to the components of Antareit;
severe renal insufficiency;
intolerance to fructose (due to the presence of sorbitol in the formulation);
children under 12 years old
with renal insufficiency (with prolonged admission, an increase in the content of magnesium and aluminum in the blood plasma is possible); Alzheimer's disease; with a low phosphate content in food (risk of developing phosphate deficiency).
Application in pregnancy and during breastfeeding
Controlled clinical studies with study of the use of the drug Antareit in pregnant women have not been carried out, however, in pre-clinical studies, the teratogenic effect or action was not detected. In connection with the lack of clinical experience, the use of Antareit during pregnancy is possible only if the benefit from its use for the mother exceeds the potential risk to the fetus. Avoid prescribing Antareit during pregnancy in large doses and for a long time. During the reception of the drug, the Antareit is not required to stop breastfeeding.
Dosing and Administration
Inside. Tablets should be thoroughly chewed or kept in the mouth until completely absorbed.
Adults and adolescents over 12 years of age: if the doctor is not recommended otherwise, 1 -2 tablets taken shortly after meals. If necessary, you can repeat Antareit after 2 hours.
The maximum daily dose for tablets is 400/20 mg - 16 tablets; for tablets 800/40 mg - 8 tablets.
Side effects of Antareit
Allergic reactions, nausea, vomiting, taste disorders, constipation, diarrhea. With long-term admission in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesia, hyperaluminia, encephalopathy, nephrocalcinosis, renal dysfunction. In patients with concomitant renal failure - a sense of thirst, lowering blood pressure, hyporeflexia.
Symptoms: with prolonged intake of high doses, kidney stones, constipation, drowsiness, hypermagnesia are possible. There may also be signs of metabolic alkalosis: mood lability, numbness or muscle pain, nervousness and fatigue, unpleasant gustatory sensations. Treatment: it is necessary to take measures to quickly remove Antareit: rinse the stomach, induce vomiting, take activated charcoal.
Interaction with other medicinal products
Antareit reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamin blockers, beta-adrenoblockers, diflunizal, isoniazid, tetracycline antibiotics, quinolones (ciprofloxacin, norfloxacin, ofloxacin, enoxacin, gropofloxacin, etc.), azithromycin, cefpodoxime , pivampicillin, rifampicin, indirect anticoagulants, barbiturates, fexofenadine, dipyridamole, zalcitabine, bile acids - chenodeoxycholic and ursodeoxycholic, penicillamine, iron and lithium preparations, quinidine, lansoprazole, mexiletine, ketoconazole.
M-holinoblokatory, slowing the emptying of the stomach, strengthen and lengthen the action of Antareit.
When using the drug Antareit and other medicines simultaneously, you should adhere to the interval of at least 1-2 hours. With long-term admission should ensure sufficient supply of phosphorus with food. With mild and moderate renal dysfunction, regular monitoring of the content of aluminum, calcium, phosphates in the blood plasma is necessary. Antareit contains sorbitol, which is contraindicated in congenital intolerance to fructose.
Features of the effect of Antareit on the ability to drive vehicles or when working with potentially dangerous mechanisms
Does not have a negative impact on the ability to drive vehicles and work with mechanisms that require increased concentration and speed of psychomotor reactions.
Form of issue
Tablets chewing 400/20 mg and 800/40 mg.
For 6 tablets in a blister of PVC / A1 foil.
For 2 or 4 blisters together with instructions for use in a cardboard box.
In dry, dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Shelf life - 3 years.
Do not use after the expiration date printed on the package.
To buy Antareit you don't need a prescription.