Sulgin tabs 500mg #20

User manual for Sulgin

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Composition

In one tablet of the preparation Sulgin contains 500 mg of sulfaguanidine.
Additional substances: calcium stearate, primogel, starch.

Form of issue

    Ten tablets in a non-jammed package - one, three or two packages in a pack of cardboard.
    Ten tablets in a non-jammed package - 6 packs in a cardboard box.
    Ten tablets in a vial - one such bottle in a cardboard pack.
    Ten tablets in a dark vial - one such bottle in a cardboard box.

pharmachologic effect

Antibacterial, antidiarrhoeic effect.

Pharmacodynamics and pharmacokinetics

Sulphaguanidine is a substance with antibacterial activity. Active against gram-positive and gram-negative microorganisms (including pathogens of intestinal infections). Poorly absorbed in when taken orally. Acts mainly in the lumen of the intestine. Competes for receptors with para-aminobenzoic acid and suppresses dihydropteroate synthetase, which leads to inhibition of the biosynthesis of tetrahydrofolic acid, which is necessary for the synthesis of pyrimidines and purines in the cell of the pathogen.

Indications for use

    Colitis or enterocolitis with symptoms of diarrhea.
    Bacterial dysentery.
    Preoperative preparation for intestinal interventions.
    Identified or suspected of carrying carriers of dysentery or typhoid fever.

Contraindications

Sensitization to the components of the drug or substances from the sulfonamide group.

Side effects

    Effects from the nervous activity: depression, headache, apathy, tremor, dizziness.
    Effects from the circulation and hematopoiesis: neutropenia, thrombocytopenia, agranulocytosis, anemia.
    Effects from the breath: bronchospasm.
    Effects of digestion: vomiting, nausea, diarrhea, gastritis, anorexia, glossitis, cholestasis, stomatitis, increased concentrations of transaminases, hepatitis.
    Effects from the genitourinary sphere: interstitial nephritis, polyuria, kidney damage, hematuria, crystalluria, hypercreatininaemia, increased urea concentration, oliguria, toxic nephropathy, anuria.
    Allergic reactions: photosensitivity, rash, itching, fever, injection of sclera, polymorphous bullous erythema, epidermal toxic necrolysis, allergic myocarditis, angioedema.
    Effects from the musculoskeletal system: myalgia, arthralgia.

Instructions for use Sulgin (Method and dosage)

With intestinal infections of an acute nature, the instruction on the use of Sulgin prescribes taking 1-2 grams of the drug on the first day of treatment up to 6 times a day, on the second and third days - 1-2 grams up to 5 times a day, on the fourth day - 1-2 grams up to 4 times a day, on the fifth day - 1-2 grams up to 3 times a day. The duration of treatment should not be more than a week. Children aged less than 3 years are prescribed 200 mg of Sulgin per kilogram of body weight per day, divided into three doses (within a week). Children aged 3 years are prescribed 400-750 mg of Sulgin to four times a day.
In carrying out the prevention of postoperative complications is recommended to take 50 mg of drug per kilogram body weight three times a day for five days before the intervention, and even within a week after surgery.

Overdose

Symptoms of overdose are typical for all sulfa drugs: nausea, vomiting, intestinal colic, fainting, headache, dizziness, depression, fever, crystalluria, haematuria.
Overdose Treatment: removal of receiving means, gastric lavage (effective during the first two hours of field overdose), excessive drinking, diuresis.

Interaction

There is no data on the features of interaction with other drugs.

Terms of sale

To buy online Sulgin you don't need a prescription.

Storage conditions

Keep away from children. Store at a temperature of less than 25 degrees.
Shelf life - three years.

special instructions

If necessary, the drug is used together with others with sulfonamides or antibacterial substances that are well absorbed from the intestine.
During treatment with the drug, Sulgin is advised to intensify diuresis and simultaneously take vitamins from group B.

Children

Not recommended for use in children under three years old.

In pregnancy and lactation

It is forbidden for use in these periods.

Reviews of Sulgin

Reviews indicate that patients are satisfied with the therapeutic effect of the drug. Symptoms of diarrhea and "intestinal poisoning" can arise almost everyone, from which tablets Sulgin effectively help.
However, despite the positive feedback, it is worthwhile to know that sulfaguanidine and preparations based on it are already banned in most developed countries because of their extreme nephrotoxicity and other serious side effects.