Trimedat tabs 200mg #30

User manual for Trimedat

You can buy Trimedat here

Composition

In 1 tablet contains 100 or 200 mg of trimethbutin maleate and auxiliary substances: corn starch, colloidal silicon dioxide, lactose, talc, magnesium stearate.

Form of issue

The medication is available in tablet form, in a package of 10, 20, 30 pieces.

pharmachologic effect

Myotropic antispasmodic, regulating the motor system of the digestive system. The active substance acts on the enkephalinergic system of the intestine, regulates peristalsis. Trimebutin has an antispasmodic effect in hyperkinesis of the smooth muscle tissue of the digestive tract, and in hypokinetic conditions stimulates the work of the intestine.
The drug enhances peristalsis and promotes gastric emptying, reduces pressure on the esophageal sphincter, acts throughout the intestine, enhances the response of the smooth muscle tissue of the large intestine to various food stimuli.
In diseases of the digestive tract associated with motor disorders, trimebutin helps restore the physiological activity of the intestine.

Pharmacodynamics and pharmacokinetics

After ingestion, the tablet is quickly absorbed into the digestive system, ensuring maximum concentration of the active substance in the blood after 1-2 hours. The bioavailability index is 4-6%. A small amount of medication penetrates the placental barrier. Biological transformation of the liver occurs in the hepatic system, and metabolites are excreted mainly in the urine.

Indications for use of Trimedat (Spectrum of destination)

From what tablets Trimedat:
    motor impairment with functional pathology of the gastrointestinal tract;
    gastroesophageal reflux disease;
    dyspeptic disorders in gastroduodenal pathology (vomiting, epigastric pain, nausea, digestive disorders of food);
    paralytic obstruction of the intestine after surgical interventions;
    irritable bowel syndrome, accompanied by pain syndrome, stool disorder, spasms, colic;
    preparation for examination of the digestive tract (endoscopic manipulation, X-ray examination).
The use of the drug in pediatric practice makes it possible to successfully dyspeptic disorders when the motility of the gastrointestinal tract is compromised.

Contraindications to prescription

The use of the drug is contraindicated in case of individual hypersensitivity to trimebutin. Tablets are not prescribed in pediatrics until they reach the age of three.

Side effects of Trimedat (Effects and reactions)

Annotation to the medication contains indications of single cases of side effects in the form of:
    impaired hearing;
    changes in the menstrual cycle;
    allergic responses;
    the appearance of anxiety.

Instructions for Trimedat (Method and Dosage)

How to take: inside, not liquid and squeezed with water. Instructions for use Trimedata recommends a standard treatment regimen: three times a day for 100-200 mg. The maximum dose is 600 mg per day.
In order to prevent the recurrence of irritable bowel syndrome, the drug is prescribed at 300 mg per day. The medicine can be taken within 4 months.
Instructions for the use of tablets in pediatric practice: 25 mg three times a day for children 3-5 years. Children 5-12 years of age are prescribed 50 mg three times a day. How to take Trimedat: before or after eating? Taking medication with food intake is not connected.

Overdose

The cases of taking large doses of trimebutin are not described and are not documented.

Interaction

The use of zotepin may lead to an extension of the anticholinergic effect. An increase in the duration of action of d-tubocurarine was recorded.

Terms of sale

You can buy Trimedat without a prescription form.

Storage conditions

Away from the sun, keep away from children. Temperature regime - up to 25 degrees Celsius.
Shelf life - 3 years.

special instructions

Embryotoxic and teratogenic effects are not revealed. Alcohol has a pronounced negative effect on the course of treatment.

With alcohol

It is unacceptable to take ethanol-containing drinks during the treatment period. Alcohol slows down metabolic processes in the hepatic system, reducing the effectiveness of the medication.

Trimedat during pregnancy (Possibility of application, reviews)

The decision on the need to appoint trimebutin is taken only by the doctor. Medication is contraindicated in the first trimester. Reviews during pregnancy: Trimedat well cures colic and spasms in diseases of the digestive system, without having a pronounced side effect.

Comments on Trimedat (General introduction)

The drug is well tolerated, acts quickly enough, relieving spasms, pain syndrome, stabilizing the work of the intestine. With constipation, the medication enhances peristalsis, providing a quick, painless emptying of the large intestine.
Admission of children, parents' reviews: with irritable bowel syndrome, the drug stabilizes motor skills, restoring the full functioning of the digestive system.
Reviews of doctors about Trimedat: an effective, affordable drug, widely used in the pathology of the digestive system.