Calcium D3 Nycomed Forte tabs #120

Calcium D3 Nycomed Forte instruction for use

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Calcium D3 Nycomed Forte refers to medicines that affect the metabolic processes of phosphorus and calcium in the body.

Composition, form of release

The medication is released in the form of chewable tablets with orange flavor, biconvex and round shape, white. The tablet does not have a cladding and may contain some impregnation. The edges of the tablet may be uneven, which is normal.
Each tablet of Calcium D3 Nycomed Forte contains calcium in the amount of 500 mg and vitamin D3 in an amount of 2 mg.
As auxiliary components, orange oil, isomalt, di- and monoglycerides of fatty acids, aspartame and sorbitol are used.
Tablets with orange flavor are packed in bottles of 100, 50 and 20 pieces.
Also, the medicine is produced in the form of chewing mint tablets having a biconvex, round shape, white color and mint flavor. The tablets have no shells, rough edges and a certain amount of inclusions are allowed.
Each tablet contains calcium in the amount of 500 mg and vitamin D3 in an amount of 2 mg.
Mint flavor, sorbitol and aspartame are used as auxiliary components.
Tablets with mint flavor are packed in bottles of 100 and 30 pieces.
The preparation is produced in the form of chewable lemon tablets having a biconvex, round shape, lemon flavor and white color. Tablets do not have shells, rough edges and some impregnations are allowed.
Each tablet contains calcium in the amount of 500 mg and vitamin D3 in an amount of 4 mg.
As auxiliary components, lemon oil, magnesium stearate, isomalt, di- and monoglycerides of fatty acids, aspartame, povidone and sorbitol are used.
Lemon tablets are packed in polyethylene bottles of 120, 60 and 30 pieces.

pharmachologic effect of Calcium D3 Nycomed Forte

Combined medicine helps to regulate the metabolism of phosphorus and calcium, namely in hair, teeth, muscles, nails and bones.
Due to the fact that the drug helps to fill the lack of trace element and vitamin in the body, the density of tissue in the bones increases, and it plays an important role in the mineralization of the dental tissue.
The microelement of calcium is an important component in the development of nerve conduction, muscle contraction, and it also refers to important components that make up the blood coagulation system. When lactating, during pregnancy and during a period of active growth, the most important is the presence of calcium in the body in the right amount.
The presence of vitamin D3 increases the absorption of calcium through the intestine.
The use of the drug helps to reduce the production of parathyroid hormone, which activates the process of leaching of the microelement of calcium from bone tissue.

Pharmacokinetics

From the total amount of the drug taken through the gastrointestinal tract, only 30% of calcium is absorbed. The microelement is excreted from the body with the help of the intestines, kidneys and sweat glands.
80% of vitamin D3 is absorbed from the entire amount of the medicine taken through the small intestine. Kolekaltsiferol is excreted from the body with the help of kidneys and intestines.

Indications for use

Medication is prescribed in the following situations:
    Complex treatment and prevention of osteoporosis and treatment of its complications, for example, fractures of bones;
    Therapy and prevention of a deficiency of a microelement of calcium and vitamin D3.

Dosing regimen

Tablets Calcium D3 Nycomed Forte can not be swallowed whole, they need to be rinsed, or chewed. It is advisable to take the reception during eating.
For preventive purposes of osteoporosis, adults are prescribed to take 1 tablet twice a day or 2 tablets once a day. When complex treatment of this disease take on the pill 2 to 3 times per day.
When replenishing the lack of vitamin and microelement, adult patients and children from 12 years of age are prescribed 2 tablets per day. Children 3-12 years old should take 1 tablet a day or so, as prescribed by the doctor in charge.
For preventive and curative purposes of osteoporosis, the duration of therapy is established by a specialist individually.
To eliminate the lack of vitamin and microelement in the body, on average, treatment lasts no less than 5 weeks. Only the attending physician individually can prescribe a repetition of treatment courses.
If the patient suffers from impaired liver function, dosage adjustments can be avoided.
If there is a kidney failure in a serious stage, the medicine should be canceled.
Older patients are prescribed a similar dosage as for adult patients. It is necessary to remember the possible decrease in the clearance of creatinine.

Overdose of Calcium D3 Nycomed Forte

When using the drug at a dosage exceeding the therapeutic norm, the following symptoms of excess calcium in the body are possible: urolithiasis, mental disorders, high fatigue, constipation, nausea, polyuria, anorexia, cardiac arrhythmia, nephrocalcinosis, pain in the bones and in the stomach , vomiting, muscle weakness, thirst.
Prolonged use of high dosages (more than 2.5 g of calcium) can lead to calcification in soft tissues and to impaired renal activity.
If there are signs of an overdose, the patient should immediately cancel the drug, and in this situation, cardiac glycosides and thiazide diuretics should not be used.
In case of an overdose, you should immediately consult a doctor who will treat with the washing of the stomach cavity, as well as the appointment of bisphosphonates, glucocorticosteroids, diuretics and calcitonin. It should be monitored the number of electrolytes in the blood, diuresis and kidney function. In difficult cases, it is necessary to measure the central venous pressure and measure the ECG.

Drug Interactions

Elevated levels of calcium in the body can increase the toxic effect of cardiac glycosides, if they are used together with a medicine containing vitamin D and calcium. In such a case, you need to regularly monitor the ECG and the amount of trace element in the blood.
Medicines containing calcium can inhibit the absorption of tetracyclines in the digestive tract. In this regard, antibiotics of this series should be taken after 5 hours or 2 hours before taking Calcium D3 Nycomed Forte.
In order not to reduce the absorption of drugs that contain bisphosphonates, they are desirable to take an hour before taking a medication containing calcium and vitamin D3.
Since glucocorticosteroids decrease the absorption of calcium, therapy with these medicines requires an increase in the dosage of the drug Calcium D3 Nycomed.
With the parallel administration of thiazide diuretics, the likelihood of hypercalcemia increases, because the tubular reabsorption of the microelement increases. With the joint intake of diuretics in this series, you must constantly determine the amount of calcium in the blood.
The microelement of calcium lowers the effect of the drug Levothyroxine, as the degree of its absorption decreases. In this regard, between taking these medications should be a time interval of 4 hours.
With parallel use of calcium medicines with antibiotics related to the quinolone group, the degree of absorption of the latter decreases. Therefore, these antibiotics should be consumed 6 hours after or 2 hours before the application of the drug with calcium.
Foods that contain fitin and oxalate lower the percentage of absorption of the trace element of calcium. In this regard, the medication should not be taken about 2 hours after meals containing cereals, spinach, rhubarb and sorrel.

Lactation and pregnancy

Patients during lactation and pregnancy are allowed to take vitamin D and calcium to eliminate their deficiency in the body.
During pregnancy per day, the dosage should be 600 IU of vitamin D3 and 1500 mg of a microelement.
Overdosing, leading to an increase in the calcium content in the body, can adversely affect the development of the fetus.
The drug is also approved for use by patients during lactation.
Vitamin and a micronutrient is able to enter breast milk, therefore, it is necessary to take into account possible variants of the intake of these substances into the body of the mother and child.

Side effects

The use of medication can lead to the appearance of side effects such as diarrhea, nausea, constipation, dyspeptic manifestations, pain in the abdomen, flatulence, urticaria, rash, itching, hypercalciuria, hypercalcemia.

Contraindications

Calcium D3 Nycomed Forte can not be administered to patients in the following situations:
    Sarcoidosis;
    Renal failure in severe form;
    Nephrolithiasis;
    Hypercalcemia;
    High sensitivity to any component of the drug;
    Tuberculosis in active form;
    Increased amount of vitamin D;
    Hypercalciuria.
Calcium D3 Nycomed Forte can not be administered to children under 3 years of age.
As the composition contains aspartame, which is converted into the body in phenylalanine, the medication can not be prescribed to patients suffering from phenylketonuria.
When assigning this medication, care should be taken during the lactation, pregnancy and patients suffering from kidney failure.

special instructions

During long treatment with Calcium D3 Nycomed Forte, the amount of creatinine and calcium in the blood should be determined regularly. This is of particular importance for elderly patients with concomitant administration of diuretics and cardiac glycosides, as well as for individuals with a high predisposition for the appearance of stones in the kidneys. If the amount of calcium in the body is increased or there are symptoms of impaired kidney function, you need to reduce the dosage or suspend therapy.
Patients suffering from kidney failure should be more careful to take medications containing vitamin D. With this disease, you need to constantly determine the amount of phosphates and calcium in the blood. Additionally, the probability of calcification in soft tissues should be considered.
In order to avoid the likelihood of an overdose, all possible sources of vitamin D intake should be considered.
Patients suffering from osteoporosis should be more careful to take medicines containing vitamin D3 and calcium, since there may be a risk of increasing the amount of calcium in the body.
Parallel administration of antibiotics of the quinolone and tetracycline group is not desirable, or this combination of drugs should be taken with extreme caution.
Calcium D3 Nycomed Forte does not affect the ability to drive vehicles or perform work with complex technical mechanisms.

Terms and conditions of storage

The drug is stored at a temperature of not more than 25 gr C, in a well-sealed vial, in a dry place, remote from small children. The medicine is allowed to be used within 3 years from the moment of its release.