Tinidazol tabs 500mg #4

Tinidazol instruction

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Composition

One tablet contains 500 mg of active ingredient Tinidazol, as well as additional components in the form of microcrystalline cellulose, crospovidone, magnesium stearate, and starch.
The composition of the shell contains elements: titanium dioxide, hydroxypropylmethylcellulose, polysorbate.

Form of issue

In tableted form.

pharmachologic effect

Antimicrobial, antiprotozoal.

Pharmacodynamics and pharmacokinetics

It is highly proliferative drug, able to penetrate into anaerobic microorganisms, trichomonads. The mechanism of action is based on the reduction with the help of nitroderductase, followed by inhibition of synthesis, a violation of the structure of DNA. Tinidazol is active against clostridia, fusobacteria, peptostreptococcus.

Indications for use of Tinidazol

From what tablets?

Indications for the use of the drug are: amoebiasis, amoebic dysentery, giardiasis, trichomoniasis, cutaneous leishmaniasis, nonspecific vaginitis, ulcerative gingivitis in acute form. The drug is effective against anaerobic infections: abscess, sepsis, peritonitis, pyosalpinx, endometritis, empyema, pneumonia. In combination therapy, Helicobacter pylori is used for eradication.

Contraindications

The drug is not prescribed for diseases of the nervous system of an organic nature, intolerance to Tinidazol, pregnancy, oppression of bone marrow hematopoiesis, breastfeeding. Do not apply in pediatrics before the age of 12 years.

Side effects

Nervous system: locomotor ataxia, fatigue, dizziness, headaches, movement coordination disorder, peripheral neuropathy, dysarthria, rarely convulsions, weakness in the whole body.
Digestive system: diarrhea, dryness of the mucous membranes of the mouth, dyspeptic disorders, "metallic" taste in the mouth, loss of appetite.
Taking the drug Tinidazol may be accompanied by allergic reactions: angioedema, skin itching. Transitory leukopenia is rare.

Instructions for use Tinidazol (Method and dosage)

Tinidazol is taken after meals, inside.
Giardiasis: once 2 grams, dosage for children is calculated individually-50 mg / kg. If the therapy is ineffective, repeat the course in the same dosage. Anti-amliasis therapy involves the simultaneous treatment of all family members, contact persons.
Urogenital trichomoniasis: once 2 grams, or three times a day for 150 milligrams for 5 days, or twice a day for 150 milligrams for a week. Treatment of vaginal trichomoniasis includes additional local treatment.
Amoebiasis of the intestine: twice a day for 600 milligrams for 5 days, or 2 grams per day for 3 days. If there is no effect on the 5th day, the treatment is extended to 10 days.
Liver amebiasis: three days at 1.5-2 milligrams per day, or 5-10 days at 600 milligrams twice a day.
Nonspecific vaginitis, ulcerative gingivitis: once 2 grams.
Anaerobic infection (clostridia, fusobacteria, etc.): the first day is 2 grams, the next days are 1 gram per day, the course of treatment is 5-6 days.
Prevention of postoperative infectious complications: 12 hours before surgery, take 2 grams of the drug.
Instructions for use Tinidazol Acry is similar.

Overdose

In case of an overdose, an increase in the severity of the side effects described above is recorded. There is no specific antidote against tinidozole, dialysis is recommended.

Interaction

Tinidazol is not compatible with antibacterial drugs (cephalosporins, rifampicin, erythromycin, aminoglycosides), sulfonamides. Phenobarbital helps accelerate the metabolic process. Tinidazol is not prescribed with ethionamide. The drug enhances the effect of indirect anticoagulants, reducing the dosage of the drug in half reduces the risk of bleeding.

Storage conditions

In a dry, dark place inaccessible to children at a temperature of 15-25 degrees Celsius.
Shelf life - three years.

special instructions

During the treatment of genital trichomoniasis, it is necessary to treat the sexual partner.
Tinidazol helps to stain the urine in a dark color.
When taking the drug for more than 6 days, a control analysis of the peripheral blood condition is required.
Data on the safety of the drug Tinidazol in the treatment of anaerobic infection in children under 12 years of age do not.
The drug affects the management of complex mechanisms, driving transport, performing complex work.

With alcohol

When the drug interacts with ethanol, disulfiram-like reactions develop, it is recommended to abstain completely from drinking alcoholic beverages throughout the treatment period.

Reviews about Tinidazol

Effective means, in particular, for the control of giardiasis, trichomoniasis, and gardnerellez. It is believed that it helps with bad breath.
Negative feedback on the forums indicates the presence of side effects, such as: dry mouth, unpleasant aftertaste, nausea.