Accupro tabs 20mg #30

Accupro instruction for use

Reed more and buy Accupro on this page

Composition

1 tablet contains the active substance of quinapril in the form of hydrochloride in the amount of 5, 10, 20 or 40 mg.

Form of issue

Produced in the form of tablets in the shell.

pharmachologic effect

ACE inhibitor.

Pharmacodynamics and pharmacokinetics

The active substance is quinapril. The mechanism of the action is aimed at the competitive blocking of the angiotensin converting enzyme, to reduce the angiotensin-1 transition rate in angiotensin-2.
Accupro increases tolerance to load, IOC, reduces wedging pressure in the capillaries of the pulmonary system, reduces afterload.
Long-term therapy triggers the reverse development of myocardial hypertrophy in patients with arterial hypertension, and in damaged, ischemic myocardium improves blood flow.
Hinapril can strengthen renal, coronary blood flow, reduce platelet aggregation.
After a single dose, the drug begins its effective effect within an hour. A full therapeutic effect is recorded within a few weeks of treatment.

Indications for use Accupro

The medication is prescribed in the renovascular form of arterial hypertension, with renal failure against scleroderma, with CHF, after a previous myocardial infarction together with other medications.

Contraindications

Accupro not appointed with intolerance of hinapril, in pregnancy, hypersensitivity to ACE inhibitors, breastfeeding.
With idiopathic, hereditary forms of angioedema, cardiovascular zabolevanii, cerebrovascular disease, diabetes, severe forms of autoimmune systemic connective tissue diseases (scleroderma, systemic lupus erythematosus), with aortic stenosis, stenosis of the arteries of two kidneys, with hyperkalemia, after surgery for kidney transplantation, pathology of the kidney system, liver, elderly people, diarrhea, vomiting Accupro appoint with caution, after the preliminary consulting specialists.

Side effects

Cardiovascular system: myocardial infarction, orthostatic collapse, ischemic type of stroke, aggravation of Raynaud's disease, worsening of the course of IHD, tachycardia, orthostatic hypotension.
Nervous system: fainting, depression, fatigue, headaches, dizziness, mood changes, paresthesia of limbs, sensitivity disorders, sleep disorders, asthenia, confusion.
Sensory organs: loss of taste perception, noise in the ears, vestibular disturbances, changes in visual perception.
Digestive system: abnormalities in the pancreas, pathology of the hepatic system, increased liver enzymes, decreased appetite, diarrhea, constipation, epigastric pain, dry mouth, hyperbilirubinemia.
Organs of hematopoiesis: pancytopenia, neutropenia, leukopenia, anemia, agranulocytosis.
Respiratory system: sinusitis, bronchospasm, bronchitis, dry cough, rhinitis.
Genitourinary system: decreased potency, delayed urination, proteniuria, hypercreatininaemia, increased urea levels, delayed urination.
It is possible to develop allergic reactions, glossitis, itching, exudative multiforme erythema, hyponatremia, hyperkalemia, myalgia, hyperthermia, exfoliative dermatitis, photosensitization, arthralgia, alopecia.

Accupro tablets, instructions for use (Method and dosage)

According to the instructions for use, Accupro is taken orally.
The initial dosage for arterial hypertension is 10 mg (in 1 or 2 admission). If the dose is ineffective, the dosage is gradually increased to 20 mg within three weeks.
The average therapeutic dosage is 10-20 mg per day, not more than 80 mg per day.
Elderly, with the pathology of the renal system, the dose is reduced to 5 mg per day.

Overdose

It is manifested by a marked drop in blood pressure, a violation of visual perception, weakness, dizziness.
Treatment by symptoms.

Interaction

Accupro strengthens the action of ethanol.
When taking procainamide, immunosuppressants, cytostatics, allopurinol, the risk of leukopenia increases.
Hinapril enhances the hypoglycemic effects of insulin, sulfonylurea and its derivatives.
Narcotic analgesics, diuretics, antihypertensives, preparations for general anesthesia increase the hypotensive effect of Accupro.
With the intake of sodium chloride, NSAIDs weaken the effect.
Potassium-sparing diuretics (triamterene, spironolokton, amiloride) potassium preparations cause hyperkalemia.
Against the background of taking estrogens, weakening of the hypotensive effect is recorded because of the fluid retention in the body.
The risk of abortion and neutropenia increases with the use of medications that depress the bone marrow.

Terms of sale

You don't need a prescription to buy Accupro online.

Storage conditions

In a place inaccessible to children at a temperature of no more than 25 degrees Celsius.
Shelf life not more than three years.

special instructions

Patients with reduced BCC, with diarrhea, vomiting, limited salt intake, taking diuretics Accupro appoint with caution because of the risk of a sharp drop in blood pressure.
With the development of transient hypotension, the drug is not abolished, the dosage is reduced, the pressure is stabilized.
With a sharp drop in blood pressure, the patient is given a horizontal position, physiological saline is injected to increase the BCC.
2-3 days before the start of therapy, it is recommended to cancel diuretic drugs, except for cases with malignant hypertension.
When decompensated CHF, with malignant flow of arterial hypertension, quinapril therapy is started in a hospital.
It is required to control the level of leukocytes, hemoglobin, potassium, urea, creatinine, liver enzymes.
The simultaneous use of dialysis membranes AN69 is inadmissible due to the risk of anaphylactoid reactions.
Newborns, whose mothers took quinapril during the treatment period, are carefully monitored in order to timely diagnose oliguria, hypotension, and hyperkalemia.
With the development of oliguria, renal perfusion is required by infusion of vasoconstrictor drugs, appropriate fluids, and maintenance of blood pressure. In infants, newborns, the development of oliguria, neurologic symptoms occurs with a drop in blood pressure, a decrease in cerebral, renal blood flow.
Accupro affects the management of motor vehicles. Patients need to be careful when doing physical work in hot weather because of the risk of dehydration and hypotension.
Before the surgical intervention of an anesthesiologist and a surgeon, one must be warned about taking the medication.

Reviews about Accupro

The reviews indicate the high effectiveness of the medication according to the indications for use. Follow the instructions without fail.