Cardiket tabs 40mg #50

Instruction for Cardiket

To buy Cardiket online just add it to your shopping cart

Composition

One tablet Cardiket Retard 20, 40 and 60 contains Isosorbide dinitrate 20, 40 and 60 mg respectively. Also in the composition are additional substances (talc, polyvinyl acetate, lactose monohydrate, potato starch, magnesium stearate).
INN: Isosorbide dinitrate.

Form of issue

The medicine is released in the form of round white tablets. Depending on the dosage, on one flat side the risk is imprinted, and the inscription 20 IR, 40 IR or 60 IR is engraved. On the other, the more convex side is the inscription SCHWARZ PHARMA.
Blisters of 10 pieces are in cardboard boxes of 1 or 5, that is, 20 or 50 tablets of prolonged action in each package.

pharmachologic effect

Vasodilatory.

Pharmacodynamics and pharmacokinetics

The active substance results in relaxation of the smooth-muscle walls of the vessels, thus expanding the peripheral veins and arteries and producing a vasodilating effect. Diastolic pressure decreases, the return of venous blood to the ventricle decreases, as well as its volumetric filling.
After taking the pill, its effect comes quickly (after 15 minutes). Bioavailability is 22%, the degree of binding to proteins is 30%. The main metabolites formed in the liver: isosorbide-2-mononitrate, isosorbit-5-mononitrate, their withdrawal is through the kidneys. Completely displayed per day.

Indications for Cardiovascular use

From what appoint or nominate tablets?
For the prevention and treatment of anginal attacks, myocardial infarction, ischemic heart disease.
Also, cardiac failure is indicated by heart failure (chronic), when combined with other drugs.

Contraindications

    drug allergy;
    vascular collapse and shock;
    strongly lowered blood pressure;
    diseases and conditions, accompanied by increased intracranial or intraocular pressure (glaucoma);
    acute myocardial infarction and hemorrhagic stroke;
    stenosis;
    head trauma;
    a decrease in the volume of circulating blood;
    combination with inhibitors of phosphodiesterase type 5 (tadalafil, sildenafil, vardenafil).
The use of the drug is not recommended, or should be under the supervision of a doctor
    in children under 18;
    with cardiac tamponade;
    pronounced anemia;
    toxic pulmonary edema;
    hypertrophic obstructive cardiomyopathy;
    with constrictive pericarditis;
    chronically low blood pressure;
    hyperthyroidism;
    severe kidney and liver diseases.

Side effects

    weakness, decreased blood pressure, angina and bradycardia, headache;
    slow reaction, drowsiness, ischemia;
    dryness of the oral mucosa, belching, nausea, stomach pain;
    redness of the face, allergic skin rash, tolerance to other nitrate medicines.

Instructions for use Cardiket (Method and dosage)

Dosage and mode of admission Cardiket Retard should be appointed by a specialist. Tablets are not chewed, washed down with water.
According to the instructions for the use of CardiKet, the daily dose can be from 60 to 80 mg, distributed to 1-3 reception. At a dosage of 20 mg, appoint 1 table. 2 times a day. As a rule, treatment starts with a lower dose and gradually increases it. It is not recommended to stop taking the medication.

Overdose

Loss of consciousness, collapse, nausea, diarrhea, anoxia, coma, respiration, redness of the skin. Treatment: 1% methylene blue intravenously, 2 mg per kg of weight of the affected person.

Interaction

With caution combine with vasodilators, calcium channel blockers, tricyclic antidepressants, alcohol, adrenoblockers, antihypertensives, neuroleptics, quinidine, novocainamide, dihydroergotamine, tadalafil, sildenafil and vardenafil.
When used with sympathomimetics and alpha-adrenoblockers, the antianginal effect of the drug is reduced. Directly on the effectiveness of the drug affect the stomach-enveloping drugs, because they reduce the rate of penetration of the active substance into the systemic bloodstream from the stomach.
Atropine and other M-holinoblokatory can increase the risk of increasing intraocular pressure.
Cardiket can and even needs to be combined with nifedipine, pananginum, amiodarone, riboxin and propranolol.

Terms of sale

To buy Cardiket the prescription is not needed.

Storage conditions

In a dark, cool place, inaccessible to children.
Shelf life - 5 years.

Reviews about Cardiket

Reviews about Cardiket are mostly positive. It is often prescribed to people with diseases and disorders in the work of the heart. Of the side effects, headaches are most common, and there are reports of very severe headaches. In any case, the drug effectively establishes the work of the heart muscle, regardless of the specific reaction of the organism in the form of side effects.