Deprenorm MV tabs 70mg #30

Deprenorm MV instruction for use

Reed more and buy Deprenorm MV online

Composition

One tablet of the agent contains 35 or 70 mg of trimetazidine dihydrochloride + auxiliary elements (microcrystalline cellulose, hydroxypropylcellulose, plastidone S-630, hydroxypropylmethylcellulose, polyethylene glycol, red iron oxide, calcium hydrogen phosphate dihydrate, colloidal silicon dioxide, magnesium stearate, polyethylene glycol, talc).

Form of issue

Deprenorm MV is produced in the form of pink tablets of prolonged action, biconvex, in the film membrane. If you split the tablet in half, you can see two layers, the substance inside - white.
The drug is released in a dosage of 35 or 70 mg, 10 or 15 pieces in cell contour packs, 2, 3, 4, 6 packs in a cardboard bundle.

pharmachologic effect

Antihypoxic.

Pharmacodynamics and pharmacokinetics

The drug has antianginal and antihypoxic activity, improves metabolic processes in the myocardium.
The active substance enhances aerobic glycolysis, inhibits the oxidation of polyunsaturated fatty acids, thus normalizing oxygen consumption and activating the oxidative decarboxylation reactions.
The drug prevents intracellular depletion of ATP and creatine phosphate, normalizes myocardial contractility, supports the normal functioning of potassium-sodium channels. The withdrawal of CPK from the cell does not occur, neutrophils in the ischemic zone are not activated. Thus, myocardial damage due to ischemia is minimized.
With systematic use, the frequency of seizures is significantly reduced, as is the patient's need for nitrates. Increased stamina, tinnitus and dizziness disappear, the condition of the retina improves.
When taking the drug, the active substance quickly enters the systemic circulation, after absorption in the gastrointestinal tract. Its maximum concentration is reached after 5 hours and during 24 hours it is maintained at 75% of the maximum.
Whether a person takes food with a medicine or not - does not matter, the pharmacokinetic indices remain the same.
The drug is excreted in the urine, through the kidneys, in an unchanged form.

Indications for use Deprenorm

The drug is prescribed:
    when dizziness occurs due to vascular disorders;
    for the prevention of angina attacks in the complex treatment;
    with cochleo-vetibular disorders, such as tinnitus, hearing problems, etc., due to ischemia;
    with chorioretinal vascular disorders.
Also, the indication for the use of the drug is the vascular pathology of the eyes, since the drug can improve the functioning of the retina.

Contraindications

The medicine is contraindicated:
    with allergies to the components of the drug;
    with renal failure, if the SC is less than 15 ml per minute;
    children and adolescents (under 18);
    at pregnancy and thoracal feeding;
    with liver diseases.

Side effects

The most likely adverse reactions are: headache, dizziness, diarrhea, nausea, asthenia, epigastric pain, vomiting, indigestion, constipation, itching, rashes on the skin, hives.
Also can occur: tremor, hot flashes, palpitation, tachycardia, a strong decrease in blood pressure, agranulocytosis, increased muscle tone, akinesia, extrasystoles, thrombocytopenia, agranulocytosis, hepatitis, impaired motor activity, Quincke's edema, drowsiness and insomnia.

Instructions for use Deprenorm (method and dosage)

Tablets are taken orally, regardless of food intake, washed down with a large amount of liquid. The tablet can not be divided or gnawed.
The duration of the drug is determined by the doctor, depending on the disease and its flow patterns.
According to the instructions for the use of Deprenorm MB 35 mg, appoint two tablets 2 times a day. If the dosage of the drug is 70 mg, then one tablet is taken 2 times a day.

Overdose

In case of an overdose, symptomatic therapy should be given.

Interaction

In patients taking antihypertensive drugs, the drug can significantly reduce the pressure, until the loss of consciousness.
Before taking the drug should consult with a specialist.

Terms of sale

To buy Deprenorm MB the prescription is not required.

Storage conditions

In a dry place, in the original packaging, at a temperature of no higher than 25 degrees.
Shelf life - 2 years.

special instructions

The medicine is not an emergency aid, it takes a long time to take the drug systematically.
If there is an attack of angina or a heart attack, you should see a doctor, review the treatment.
The medicine can cause or worsen the symptoms of parkinsonism. If they occur, you should cancel the drug, review the treatment. Symptoms tend to go away for 4 months after drug withdrawal. If after this time the symptoms do not disappear, neurologist consultation is required.

Reviews about Deprenorm

Reviews about the drug are good. Patients forget about attacks of angina pectoris, stop taking more toxic drugs, feel much better, normally suffer physical stress. Adverse reactions are rare.