Idrinol caps 250mg #40
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Idrinol user manualTo buy online Idrinol just add it to your shopping cartCompositionIn 1 ml of the solution, 100 mg of meldonia dihydrate.Form of issueSolution in ampoules for intravenous administration.pharmachologic effectMetab..
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Idrinol user manual
To buy online Idrinol just add it to your shopping cart
Composition
In 1 ml of the solution, 100 mg of meldonia dihydrate.
Form of issue
Solution in ampoules for intravenous administration.
pharmachologic effect
Metabolic.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The active substance is an analogue of gamma-butyrobetaine, which has a vasodilating effect. Reducing the concentration of carnitine causes an increase in the synthesis of gamma-butyrobetaine. Meldonium reduces the synthesis of carnitine, reduces the transport of fatty acids into the cell and prevents the accumulation of under-oxidized fatty acids in cells.
Pharmacological effects of the drug are manifested by increased efficiency and a positive effect on the heart. The use of myocardial infarction reduces the area of necrosis. When ischemia regulates the balance between oxygen delivery and its consumption in cells, affecting the transport of ATP. However, it can not be called a first-line drug for acute coronary insufficiency. In the presence of heart failure and angina reduces the frequency of attacks, improves myocardial contractility. With ischemic strokes, it improves circulation in the ischemic zone. Effective in the pathology of the fundus of the vascular genesis. Eliminates disturbances of the nervous system in chronic alcoholism.
Pharmacokinetics
Cmax in plasma is achieved almost immediately after administration. The active substance is metabolized with the formation of two metabolites. It is excreted by the kidneys. T1 / 2 - 3-6 hours.
Indications for use
In the complex treatment:
angina pectoris, myocardial infarction in the early post-infarction period;
chronic heart failure;
ischemic stroke and cerebrovascular insufficiency of various genesis;
dyshormonal cardiomyopathy;
abstinence syndrome with alcoholism;
hemorrhages in the retina, retinal vein thrombosis, retinopathy;
reduced working capacity and physical overstrain.
Contraindications
intracranial hypertension;
hypersensitivity;
age under 18, since safety is not established;
pregnancy, breast-feeding.
With caution, the drug is prescribed for liver and kidney pathology.
Side effects
Before you buy Idrinol you should know that the drug can cause unwanted reactions that are rare:
tachycardia;
increase or decrease in blood pressure;
psychomotor agitation;
dyspeptic disorders;
skin itching, hyperemia of the skin, rash, swelling of Quincke;
general weakness;
on the part of the blood - eosinophilia.
Idrinol, instructions for use (Method and dosage)
The drug is used intravenously and parabulbar. Idrinol intramuscularly to apply is not desirable in view of decrease in efficiency. Apply in the morning, because it is exciting.
In cardiovascular diseases - intravenously from 500 mg to 1000 mg (5-10 ml of solution). The dose is given once or divided into 2 injections. The duration of the course is 10-14 days. It is possible to conduct repeated courses several times a year.
In cases of cerebral circulation disorders, 500 mg (5 ml of solution) once a day, with a course of 10 days.
With a decrease in working capacity and excessive loads - 500 mg once a day, the course is 14 days.
With an abstinence syndrome - 500 mg 2 times a day, up to 14 days.
With ophthalmic diseases parabulbarno 50 mg, a course of 10 days.
Overdose
It is manifested by lowering blood pressure, headache, weakness, dizziness and tachycardia. Symptomatic treatment is performed.
Interaction
Enhances the effects of cardiac glycosides. The drug is well combined with antianginal drugs, antiaggregants, anticoagulants, diuretics, antiarrhythmics and bronchodilators.
It is possible to develop unexpressed tachycardia and lower blood pressure in combination with Nitroglycerin, alpha-adrenoblockers, Nifedipine, peripheral vasodilators.
Storage conditions
The drug should not be frozen. Storage temperature up to 25 ° C.
Shelf life - 3 years.
Reviews about Idrinol
Medicinal products of metabolic action are prescribed in complex treatment, which generally improves the overall condition of the patient, therefore, it is sometimes difficult to conclude that this particular drug is effective. This is often written in their reviews of visitors to forums. Many injections of Idrinol were prescribed for angina pectoris within 10 days. Patients noted a significant decrease in the frequency of attacks of pain in the heart and arrhythmia, a decrease in the dose of nitroglycerin on the background of treatment. Significantly increased endurance physical activity.
"After the stroke they stabbed idrinol in the hospital and continued at home - the memory improved and the sight became better." Another recall also noted improvement in memory and vision. The drug was well tolerated. No adverse reactions were noted.