Trombless Plus gel 1000ME/gr 50gr

Trombless Plus instruction for use

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See also - Trombless

Indications for use

- symptomatic complex of chronic venous insufficiency (including against the background of varicose veins of the lower extremities), migrating phlebitis, thrombophlebitis of superficial veins;
- subcutaneous hematomas, localized edema and aseptic infiltrates;
- injuries and bruises of joints, tendons, muscle tissue;
- complications arising after surgical operations on the veins.

Dosage form

gel for external use

Contraindications for Trombless Plus

- hypersensitivity to the components of the drug;
- open infected wounds or wounds with heavy exudation at the site of the intended application;
- Children under 18 years of age (due to the lack of data on the effectiveness and safety of the drug in this group);
- pregnancy and lactation.
With care, it is necessary to use Trombless Plus with an increased tendency to bleeding, thrombocytopenia.

Dosing and Administration (Instruction)

Trombless Plus is applied externally, applied a thin layer on the skin above the affected area and around it, evenly spreading on the surface of the skin with light circular motions 2-3 times a day. The course of treatment is 2-3 weeks, with the recurrence of a relapse of the disease.
When trophic ulcers with slight exudation of the wound surface before applying purified by exudate and necrotic tissue, if necessary washed with a solution of 3% hydrogen peroxide, nitrofural 1: 5000 or chlorhexidine 0.05% and dried. The gel is applied in a uniform thin layer over the entire affected area and a sterile gauze bandage is applied. Change dressings produced 1 time per day. With the open method of treatment, the drug is applied 1-2 times a day. The duration of treatment is determined by the dynamics of epithelialization.
With subcutaneous hematomas, localized edema, aseptic infiltrates, injuries, bruises and similar conditions, apply to the affected area 2-3 times a day until the normal state of the damaged tissue is completely restored.

Pharmachologic effect

Trombless Plus is a combined drug.
Heparin sodium is an anticoagulant of direct action, it has anti-inflammatory, antiproliferative, anti-edema and analgesic effect. Reduces the aggregation of platelets, increases the fibrinolytic properties of the blood. It improves microcirculation and activates tissue metabolism, thereby accelerating the processes of resorption of hematomas and thrombi, eventually restoring the permeability of veins, clinically it is accompanied by a pronounced analgesic and anti-inflammatory effect.
Dexpanthenol - provitamin B5 - the skin is transformed into pantothenic acid that is part of coenzyme A, which is involved in the acetylation processes, carbohydrate and fat metabolism; stimulates the regeneration of the skin, normalizes the cellular metabolism, increases the strength of collagen fibers. It has a regenerating, vitamin, metabolic and anti-inflammatory effect.
Troxerutin is a flavonoid (derivative of the routine), has P-vitamin activity; has venotonic, angioprotective, anti-edematous, antioxidant and anti-inflammatory effects. Reduces the permeability and fragility of capillaries, increases their tone. Increases the density of the vascular wall, reduces exudation of the liquid part of the plasma and diapedesis of blood cells. Reduces inflammation in the vascular wall, limiting the adhesion to its surface of platelets.
Benzocaine is a local anesthetic for surface anesthesia. Prevents the appearance of painful impulses in the endings of the sensory nerves and their conduction along nerve fibers. Benzocaine expands the surface vessels, contributing to the absorption of heparin.

Side effects of Trombless Plus

With prolonged use of the drug, local reactions in the form of skin hyperemia, decreased sensitivity (at the site of application), allergic reactions (skin rash, itching) are possible.
No cases of drug overdose have been reported.

Special instructions

Trombless Plus is not intended for use in ophthalmology, for intravaginal administration.

Interaction

The combined use of a gel with oral anticoagulants can cause prolonged prothrombin time.
Non-narcotic analgesics and anticholinesterase drugs increase the effect of the benzocaine included in the preparation.
Benzocaine reduces the antibacterial activity of sulfonamides.

Terms of sell

You can buy Trombless Plus without a prescription