Valsartan tabs 160mg #30

Valsartan user manual

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Composition

The preparation contains valsartan as an active ingredient.
Tablets of 40 mg include the following additional components: magnesium stearate, croscarmellose sodium, microcrystalline cellulose, dye "Opadrai pink".
Tablets of 80 and 160 mg contain the following auxiliary elements: croscarmellose sodium, magnesium stearate, dye "Opadrai pink", microcrystalline cellulose, aerosil.

Form of issue

The medicine is sold in pharmacies in the form of powder, capsules, granules and tablets.

pharmachologic effect

Antihypertensive drug.

Pharmacodynamics and pharmacokinetics

The active substance of the drug provokes a competitive blocking of the AT1 angiotensin II receptors, which are located in the vascular endothelium, cardiac muscle, adrenal cortex, renal tissue, brain and lung tissue. This leads to inhibition of angiotensin effects. The drug reduces myocardial hypertrophy in hypertension.
After a single application, the effect is noticeable after 120 minutes, it lasts throughout the day. A strong therapeutic effect is achieved 3 weeks after the first day of the course.
In people with CHF, the drug eliminates hyperstimulation of RAAS, prevents pathological proliferation of cells, reduces swelling. Its reception reduces preload and increases cardiac output.
When combined with Captopril reduces the likelihood of postinfarction complications.
In addition, a combination such as valsartan and amlodipine is common. These active ingredients are contained in medicines such as Exforge and Vamloset.
The original preparation is quickly absorbed from the digestive tract. Bioavailability on average - 23%.
The connection with plasma proteins (mainly with albumins) is about 95%.
Excreted mainly with feces (70%), also excreted in the urine (30%), mostly unchanged.

Indications for use

The drug is used in arterial hypertension, as well as to improve the survival of people with acute myocardial infarction, which is complicated by left ventricular systolic dysfunction and / or left ventricular failure. In the case of chronic heart failure is used as a component of complex treatment.

Contraindications

Do not use if hypersensitivity to the components of the drug, pregnancy, breastfeeding. For children, the efficacy and safety of the remedy are not established.

Side effects

Taking this medication can cause some undesirable effects:
    SSS and hematopoiesis system: neutropenia, decrease in hematocrit, hyperkalemia;
    CNS: dizziness, weakness, headache;
    gastrointestinal tract: diarrhea, abdominal pain, nausea, increased activity of hepatic transaminases;
    Other: cough, viral infections, hyperkalemia.
Adverse reactions with the use of the drug are rare.

Instructions for use of Valsartan (Method and dosage)

For those who use Valsartan, the instructions for use indicate that the product is intended for oral use. The recommended dosage for arterial hypertension is 80 mg. Norm for the day take in one go. If necessary, the dosage can be increased to 160 mg or another use of another antihypertensive drug. Instructions for use Valsartan indicates that the maximum daily dosage is 320 mg. It is not recommended to exceed it.

Overdose

Symptoms of overdose - hypotension, bradycardia, tachycardia. The treatment is symptomatic. Dialysis is not effective.

Interaction

The drug enhances the effect of diuretics. Medicines that include potassium as well as potassium-sparing diuretics increase the likelihood of hyperkalemia.

Terms of sale

To buy Valsartan the prescription is not needed.

Storage conditions

Temperature up to 25 ° C. Keep the drug in a place that is protected from light and inaccessible to children.
Shelf life - three years. Do not use after the expiry date printed on the package.

Reviews about Valsartan

Reviews about Valsartan are mostly approving. Those who used this remedy note its quick action. The doctors' comments also indicate a pronounced hypotensive activity of the drug.